adisease

Showing entry for Holoprosencephaly

General Disease Information
BXGD Id	BXGD003081
Disease Name	Holoprosencephaly
Disease CUI Id	C0079541
MeSH Codes	C16 C05 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id	DOID:630 DOID:7 DOID:225 DOID:0080015
Disease Ontology Class Name	genetic disease; disease of anatomical entity; syndrome; physical disorder
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A5YKK6	BXGT001378	CCR4-NOT transcription complex subunit 1	23019	reviewed	Transcription factor
O00522	BXGT003935	Krev interaction trapped protein 1	889	reviewed
O43683	BXGT004614	Mitotic checkpoint serine/threonine-protein kinase BUB1	699	reviewed	Kinase
O60566	BXGT004884	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	701	reviewed	Kinase
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P48449	BXGT010632	Lanosterol synthase	4047	reviewed
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P60763	BXGT011327	Ras-related C3 botulinum toxin substrate 3	5881	reviewed	Enzyme modulator
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15465	BXGT013573	Sonic hedgehog protein	6469	reviewed
Q15796	BXGT013599	Mothers against decapentaplegic homolog 2	4087	reviewed	Transcription factor
Q4KMG0	BXGT014850	Cell adhesion molecule-related/down-regulated by oncogenes	50937	reviewed
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme
Q9UHD8	BXGT021698	Septin-9	10801	reviewed	Enzyme modulator
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9UPZ9	BXGT021804	Serine/threonine-protein kinase ICK	22858	reviewed	Kinase
Q9Y5W5	BXGT022303	Wnt inhibitory factor 1	11197	reviewed	Calcium-binding protein
Q7Z624	BXGT022792	Calmodulin-lysine N-methyltransferase	79823	reviewed
Q15583	BXGT024027	Homeobox protein TGIF1	7050	reviewed	Enzyme
P0DP25	BXGT024595	Calmodulin-3	808	reviewed
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
Q9UKB1	BXGT025928	F-box/WD repeat-containing protein 11	23291	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}