Showing entry for Suppressor of fused homolog


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021778
Protein NameSuppressor of fused homolog
Uniport IdQ9UMX1
GeneSUFU
Gene Id51684
DomainSUFU; SUFU_C
Pfam PF05076   PF12470  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04340 Hedgehog signaling pathway
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05217 Basal cell carcinoma
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035904 aorta development
Biological Process GO:0060976 coronary vasculature development
Biological Process GO:0042994 cytoplasmic sequestering of transcription factor
Biological Process GO:0001947 heart looping
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0043433 negative regulation of DNA-binding transcription factor activity
Biological Process GO:0045668 negative regulation of osteoblast differentiation
Biological Process GO:0042308 negative regulation of protein import into nucleus
Biological Process GO:0045879 negative regulation of smoothened signaling pathway
Biological Process GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:0001843 neural tube closure
Biological Process GO:0006508 proteolysis
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0007165 signal transduction
Biological Process GO:0001501 skeletal system development
Biological Process GO:0043588 skin development
Biological Process GO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
Biological Process GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification
Biological Process GO:0003281 ventricular septum development
molecular function GO:0008013 beta-catenin binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0003714 transcription corepressor activity
molecular function GO:0008134 transcription factor binding
cellular component GO:0097546 ciliary base
cellular component GO:0097542 ciliary tip
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5610780 Degradation of GLI1 by the proteasome
R-HSA-5610780 Degradation of GLI1 by the proteasome
R-HSA-5610783 Degradation of GLI2 by the proteasome
R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome
R-HSA-5610787 Hedgehog 'off' state
R-HSA-5610787 Hedgehog 'off' state
R-HSA-5632684 Hedgehog 'on' state
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002448 BXGD000115 Ameloblastoma Neoplasms
C0002453 BXGD000117 Amenorrhea Pathological Conditions, Signs and Symptoms
C0003706 BXGD000215 Arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004604 BXGD000278 Back Pain Pathological Conditions, Signs and Symptoms
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004779 BXGD000291 Basal Cell Nevus Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0005890 BXGD000345 Body Height
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0008297 BXGD000522 Choanal Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0008924 BXGD000574 Cleft upper lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010964 BXGD000692 Dandy-Walker Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013456 BXGD000843 Earache Pathological Conditions, Signs and Symptoms; Otorhinolaryngologic Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014065 BXGD000884 Congenital cerebral hernia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0015469 BXGD000996 Facial paralysis Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Stomatognathic Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016045 BXGD001037 fibroma Neoplasms
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017654 BXGD001136 Glomerular Filtration Rate
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018552 BXGD001202 Hamartoma Neoplasms
C0018681 BXGD001214 Headache Pathological Conditions, Signs and Symptoms
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018916 BXGD001245 Hemangioma Neoplasms
C0018989 BXGD001263 Hemiparesis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0019294 BXGD001314 Hernia, Inguinal Pathological Conditions, Signs and Symptoms
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0021167 BXGD001487 Incontinence Nervous System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026010 BXGD001886 Microphthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0027498 BXGD001994 Nausea and vomiting Pathological Conditions, Signs and Symptoms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0027830 BXGD002046 neurofibroma Neoplasms; Nervous System Diseases
C0027962 BXGD002064 Melanocytic nevus Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028866 BXGD002094 Oculomotor Nerve Paralysis Eye Diseases; Nervous System Diseases
C0029089 BXGD002107 Ophthalmoplegia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030353 BXGD002213 Papilledema Eye Diseases; Nervous System Diseases
C0035411 BXGD002547 Rhabdomyoma Neoplasms
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0037293 BXGD002684 Skin tag Pathological Conditions, Signs and Symptoms; Neoplasms; Skin and Connective Tissue Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0039070 BXGD002787 Syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0039685 BXGD002825 Tetralogy of Fallot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0040264 BXGD002857 Tinnitus Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0040411 BXGD002859 Tongue Neoplasms Neoplasms; Stomatognathic Diseases
C0040997 BXGD002894 Trigeminal Neuralgia Nervous System Diseases; Stomatognathic Diseases
C0042024 BXGD002949 Urinary Incontinence Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042025 BXGD002950 Urinary Stress Incontinence Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0079541 BXGD003081 Holoprosencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0080178 BXGD003107 Spina Bifida Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085633 BXGD003216 Mood swings Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0086543 BXGD003294 Cataract Eye Diseases
C0149951 BXGD003392 Ovarian Fibromata Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151526 BXGD003432 Premature Birth Female Urogenital Diseases and Pregnancy Complications
C0151740 BXGD003468 Intracranial Hypertension Nervous System Diseases
C0152427 BXGD003590 Polydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0152438 BXGD003592 Sprengel deformity Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0155285 BXGD003782 Orbital cyst Pathological Conditions, Signs and Symptoms; Neoplasms; Eye Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0200638 BXGD004043 Eosinophil count procedure
C0200641 BXGD004044 Blood basophil count (lab test)
C0201976 BXGD004063 Creatinine measurement, serum (procedure)
C0205833 BXGD004130 Medullomyoblastoma Neoplasms
C0205834 BXGD004131 Meningiomas, Multiple Neoplasms; Nervous System Diseases
C0206656 BXGD004219 Embryonal Rhabdomyosarcoma Neoplasms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220697 BXGD004324 POLYDACTYLY, POSTAXIAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0220998 BXGD004359 Hypothalamic hypothyroidism Endocrine System Diseases
C0221184 BXGD004402 Bitemporal Hemianopia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0221356 BXGD004448 Brachycephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221357 BXGD004449 Brachydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0235833 BXGD004775 Congenital diaphragmatic hernia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0240063 BXGD005015 Coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0241011 BXGD005073 Low serum estradiol levels
C0241240 BXGD005089 Tall stature
C0241397 BXGD005095 Triphalangeal thumb Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0242343 BXGD005153 Panhypopituitarism Nervous System Diseases; Endocrine System Diseases
C0242350 BXGD005154 Erectile dysfunction Male Urogenital Diseases; Mental Disorders
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0265677 BXGD005564 Congenital hemivertebra Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0265695 BXGD005566 Congenital fusion of ribs Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266174 BXGD005626 Duodenal atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0266362 BXGD005657 Ambiguous Genitalia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0266435 BXGD005668 Congenital hypoplasia of penis Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266551 BXGD005693 Congenital coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266623 BXGD005702 Congenital anomaly of neck Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266667 BXGD005707 Cyclocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0270680 BXGD006083 Posterior fossa compression syndrome
C0270685 BXGD006084 Cerebral calcification Nutritional and Metabolic Diseases; Nervous System Diseases
C0271270 BXGD006178 Oculovestibuloauditory syndrome Eye Diseases; Nervous System Diseases; Cardiovascular Diseases
C0271623 BXGD006222 Hypogonadotropic hypogonadism Endocrine System Diseases
C0278152 BXGD006503 Hemifacial Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Stomatognathic Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279612 BXGD006650 Childhood Embryonal Rhabdomyosarcoma Neoplasms
C0311394 BXGD006884 Difficulty walking Pathological Conditions, Signs and Symptoms
C0334482 BXGD007085 Fetal rhabdomyoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0338591 BXGD007204 Amnesia, Transient Global Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0342422 BXGD007479 Pituitary gland enlarged Nervous System Diseases; Endocrine System Diseases
C0345392 BXGD007732 Congenital kyphoscoliosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0345397 BXGD007734 Accessory rib Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0345996 BXGD007761 Milium Cyst Pathological Conditions, Signs and Symptoms; Neoplasms; Skin and Connective Tissue Diseases
C0347515 BXGD007858 Spinal Meningioma Neoplasms; Nervous System Diseases
C0349588 BXGD007933 Short stature
C0349604 BXGD007934 Intracranial Meningioma Neoplasms; Nervous System Diseases
C0349658 BXGD007947 Trichoepithelioma Neoplasms
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0399526 BXGD008251 Class III malocclusion Stomatognathic Diseases
C0423113 BXGD008473 Telecanthus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0423776 BXGD008508 Palmar pit
C0424711 BXGD008541 Orbital separation diminished
C0426817 BXGD008585 Short ribs
C0431399 BXGD008684 Familial aplasia of the vermis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Male Urogenital Diseases
C0431904 BXGD008713 Ulnar polydactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0456909 BXGD008883 Blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0476405 BXGD008993 Lung function testing abnormal
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0557874 BXGD009444 Global developmental delay
C0575158 BXGD009515 Kyphoscoliosis deformity of spine Musculoskeletal Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600033 BXGD009682 Acquired Kyphoscoliosis Musculoskeletal Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0694563 BXGD009854 Excessive daytime somnolence
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0751291 BXGD010379 Desmoplastic Medulloblastoma Neoplasms
C0751495 BXGD010473 Seizures, Focal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0796147 BXGD010803 Acrocallosal Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0812437 BXGD010850 Oculo-dento-digital syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0856825 BXGD011118 Acute GVH disease Immune System Diseases
C0871470 BXGD011316 Systolic Pressure
C0878773 BXGD011391 Overactive Bladder Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1096654 BXGD011637 Cardiac fibroma Neoplasms; Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1275668 BXGD012090 Melanotic medulloblastoma Neoplasms
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332852 BXGD012547 Cardiac rhabdomyoma Neoplasms; Cardiovascular Diseases
C1333989 BXGD012669 Familial meningioma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C1334410 BXGD012705 Localized Primitive Neuroectodermal Tumor Neoplasms
C1334957 BXGD012747 Neoplasm of the posterior pituitary Neoplasms; Nervous System Diseases; Endocrine System Diseases
C1334970 BXGD012750 Medulloblastoma with extensive nodularity Neoplasms
C1368275 BXGD012897 Pigmented Basal Cell Carcinoma Neoplasms
C1397139 BXGD012995 Calcification of falx cerebri
C1519383 BXGD013237 Smoking Behaviors Behavior and Behavior Mechanisms
C1527304 BXGD013266 Allergic Reaction Immune System Diseases
C1609433 BXGD013438 Congenital absence of kidneys syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1611743 BXGD013456 Familial (FPAH)
C1695776 BXGD013497 Vertebral wedging
C1698196 BXGD013513 Muscle Weakness Upper Limb Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1708604 BXGD013608 Keratocystic Odontogenic Tumor Neoplasms
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1836296 BXGD014105 Muscle Weakness Lower Limb Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1836542 BXGD014129 Depressed nasal bridge
C1836623 BXGD014139 Decreased circulating cortisol level Immune System Diseases; Endocrine System Diseases
C1838652 BXGD014330 SPLIT-HAND/FOOT MALFORMATION 3 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1839767 BXGD014404 Tented upper lip vermilion
C1840077 BXGD014434 Anteverted nostril
C1840235 BXGD014436 SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C1840238 BXGD014437 Midnasal stenosis
C1840309 BXGD014444 Short 4th metacarpal
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C1848395 BXGD014921 Large for gestational age Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C1849367 BXGD015046 Nasal bridge wide
C1849570 BXGD015067 Progressive pulmonary function impairment Respiratory Tract Diseases
C1852301 BXGD015273 Plantar pits
C1853141 BXGD015307 Slow decrease in visual acuity
C1853737 BXGD015356 Prominent occiput
C1854114 BXGD015383 Short nose
C1854301 BXGD015391 Motor delay Mental Disorders
C1856872 BXGD015647 Down-sloping shoulders
C1857126 BXGD015678 Parietal bossing
C1857679 BXGD015735 Sloping forehead
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1859436 BXGD015888 Weak extraocular muscles Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C1859680 BXGD015917 Broad face
C1860493 BXGD015987 Abnormality of the sternum
C1861324 BXGD016029 Short philtrum
C1861403 BXGD016045 Variable expressivity
C1861866 BXGD016087 Aplasia/Hypoplasia of the corpus callosum
C1862304 BXGD016120 Hamartomatous polyp of stomach Digestive System Diseases; Neoplasms
C1862313 BXGD016121 Short distal phalanx of the thumb
C1865060 BXGD016292 Molar tooth sign on MRI
C1866129 BXGD016375 Abnormality of the cerebellum Nervous System Diseases
C1866134 BXGD016378 Wide anterior fontanel
C1866959 BXGD016429 Sella Turcica, Bridged Nervous System Diseases; Endocrine System Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C2931760 BXGD018059 Acrocallosal syndrome, Schinzel type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2937358 BXGD018159 Cerebral Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C3179349 BXGD018550 Gastrointestinal Stromal Sarcoma Digestive System Diseases; Neoplasms
C3278509 BXGD018742 Spinal fusion
C3279222 BXGD018751 Aplasia/Hypoplasia of the cerebellum
C3489733 BXGD018945 Oculomotor apraxia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases; Behavior and Behavior Mechanisms; Cardiovascular Diseases
C3551915 BXGD019148 MENINGIOMA, FAMILIAL, SUSCEPTIBILITY TO
C3665349 BXGD019280 Secondary hypothyroidism Endocrine System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C4021206 BXGD020578 Chromosomal breakage induced by ionizing radiation Pathological Conditions, Signs and Symptoms
C4021655 BXGD020723 Abnormality of the sense of smell
C4021726 BXGD020735 EMG: myopathic abnormalities Musculoskeletal Diseases; Nervous System Diseases
C4021792 BXGD020783 Abnormality of the clavicle
C4021850 BXGD020819 Increased sensitivity to ionizing radiation
C4022395 BXGD020896 Abnormality of the mediastinum
C4022775 BXGD020998 Focal T2 hypointense thalamic lesion
C4022798 BXGD021001 Abnormal brain FDG positron emission tomography
C4023205 BXGD021143 Neoplasm of the anterior pituitary Neoplasms; Nervous System Diseases; Endocrine System Diseases
C4023215 BXGD021147 Abnormality of central sensory function
C4024716 BXGD021383 Secondary growth hormone deficiency
C4025374 BXGD021654 Irregular ossification of hand bones
C4025669 BXGD021720 Decreased circulating ACTH level
C4072889 BXGD022012 Decreased circulating follicle stimulating hormone level
C4072890 BXGD022013 Decreased circulating luteinizing hormone level
C4073006 BXGD022032 Visual acuity test abnormality
C4073063 BXGD022034 Abnormal kinetic perimetry test
C4073137 BXGD022045 Decreased serum testosterone level
C4277690 BXGD022377 Ciliopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C4282128 BXGD022420 PATENT DUCTUS ARTERIOSUS 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4540342 BXGD023255 JOUBERT SYNDROME 32
C4551564 BXGD023352 Narrow nasal bridge
C4551722 BXGD023402 Encephalocele Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Nervous System Diseases
C4552960 BXGD023530 Ear Pain, CTCAE
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721788 BXGD023771 Bifid ribs
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein