Showing entry for Autoimmune thrombocytopenia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD005179
Disease NameAutoimmune thrombocytopenia
Disease CUI IdC0242584
MeSH Codes C20   C15  
Disease Class NameImmune System Diseases; Hemic and Lymphatic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0002715   HP:0001871  
Human Phenotype Ontology TermAbnormality of the immune system; Abnormality of blood and blood-forming tissues
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O95243 BXGT005362 Methyl-CpG-binding domain protein 4 8930 reviewed Enzyme
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02749 BXGT005941 Beta-2-glycoprotein 1 350 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07359 BXGT006612 Platelet glycoprotein Ib alpha chain 2811 reviewed Receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08514 BXGT006781 Integrin alpha-IIb 3674 reviewed
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P12318 BXGT007799 Low affinity immunoglobulin gamma Fc region receptor II-a 2212 reviewed Cell adhesion
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16109 BXGT008194 P-selectin 6403 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P43489 BXGT010394 Tumor necrosis factor receptor superfamily member 4 7293 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55899 BXGT011131 IgG receptor FcRn large subunit p51 2217 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96PD4 BXGT019705 Interleukin-17F 112744 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9HCN6 BXGT020535 Platelet glycoprotein VI 51206 reviewed Receptor
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P20809 BXGT025043 Interleukin-11 3589 reviewed
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease