Showing entry for Tyrosine-protein kinase SYK


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010386
Protein NameTyrosine-protein kinase SYK
Uniport IdP43405
GeneSYK
Gene Id6850
DomainPkinase_Tyr; SH2
Pfam PF07714   PF00017  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04064 NF-kappa B signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04151 PI3K-Akt signaling pathway
5. Organismal Systems 5.8 Development hsa04380 Osteoclast differentiation
5. Organismal Systems 5.1 Immune system hsa04611 Platelet activation
5. Organismal Systems 5.1 Immune system hsa04625 C-type lectin receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04650 Natural killer cell mediated cytotoxicity
5. Organismal Systems 5.1 Immune system hsa04662 B cell receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04664 Fc epsilon RI signaling pathway
5. Organismal Systems 5.1 Immune system hsa04666 Fc gamma R-mediated phagocytosis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05152 Tuberculosis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05167 Kaposi sarcoma-associated herpesvirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05168 Herpes simplex virus 1 infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05169 Epstein-Barr virus infection
6. Human Diseases 6.1 Cancers: Overview hsa05203 Viral carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007257 activation of JUN kinase activity
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0001525 angiogenesis
Biological Process GO:0009887 animal organ morphogenesis
Biological Process GO:0050853 B cell receptor signaling pathway
Biological Process GO:0043366 beta selection
Biological Process GO:0048514 blood vessel morphogenesis
Biological Process GO:0030154 cell differentiation
Biological Process GO:0071404 cellular response to low-density lipoprotein particle stimulus
Biological Process GO:0071226 cellular response to molecule of fungal origin
Biological Process GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway
Biological Process GO:0042742 defense response to bacterium
Biological Process GO:0038095 Fc-epsilon receptor signaling pathway
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0045087 innate immune response
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0038110 interleukin-2-mediated signaling pathway
Biological Process GO:0038156 interleukin-3-mediated signaling pathway
Biological Process GO:0002366 leukocyte activation involved in immune response
Biological Process GO:0007159 leukocyte cell-cell adhesion
Biological Process GO:0019370 leukotriene biosynthetic process
Biological Process GO:0001945 lymph vessel development
Biological Process GO:0002281 macrophage activation involved in immune response
Biological Process GO:0002283 neutrophil activation involved in immune response
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:0030168 platelet activation
Biological Process GO:0046638 positive regulation of alpha-beta T cell differentiation
Biological Process GO:0046641 positive regulation of alpha-beta T cell proliferation
Biological Process GO:0045579 positive regulation of B cell differentiation
Biological Process GO:0045780 positive regulation of bone resorption
Biological Process GO:0050850 positive regulation of calcium-mediated signaling
Biological Process GO:0033630 positive regulation of cell adhesion mediated by integrin
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0050715 positive regulation of cytokine secretion
Biological Process GO:0045588 positive regulation of gamma-delta T cell differentiation
Biological Process GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
Biological Process GO:0032733 positive regulation of interleukin-10 production
Biological Process GO:0032735 positive regulation of interleukin-12 production
Biological Process GO:0032752 positive regulation of interleukin-3 production
Biological Process GO:0032753 positive regulation of interleukin-4 production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0051712 positive regulation of killing of cells of other organism
Biological Process GO:0043306 positive regulation of mast cell degranulation
Biological Process GO:0071639 positive regulation of monocyte chemotactic protein-1 production
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0031334 positive regulation of protein-containing complex assembly
Biological Process GO:0002092 positive regulation of receptor internalization
Biological Process GO:0032930 positive regulation of superoxide anion generation
Biological Process GO:0042535 positive regulation of tumor necrosis factor biosynthetic process
Biological Process GO:0032481 positive regulation of type I interferon production
Biological Process GO:0006606 protein import into nucleus
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0031623 receptor internalization
Biological Process GO:0090237 regulation of arachidonic acid secretion
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0051090 regulation of DNA-binding transcription factor activity
Biological Process GO:0070372 regulation of ERK1 and ERK2 cascade
Biological Process GO:0043313 regulation of neutrophil degranulation
Biological Process GO:0050764 regulation of phagocytosis
Biological Process GO:0010543 regulation of platelet activation
Biological Process GO:0090330 regulation of platelet aggregation
Biological Process GO:0032928 regulation of superoxide anion generation
Biological Process GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
Biological Process GO:0002554 serotonin secretion by platelet
Biological Process GO:0002223 stimulatory C-type lectin receptor signaling pathway
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Biological Process GO:0016032 viral process
molecular function GO:0005524 ATP binding
molecular function GO:0005178 integrin binding
molecular function GO:0016170 interleukin-15 receptor binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0019902 phosphatase binding
molecular function GO:0001784 phosphotyrosine residue binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0042169 SH2 domain binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0035325 Toll-like receptor binding
cellular component GO:0019815 B cell receptor complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0032009 early phagosome
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0042101 T cell receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-109582 Hemostasis
R-HSA-114604 GPVI-mediated activation cascade
R-HSA-114604 GPVI-mediated activation cascade
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280218 Adaptive Immune System
R-HSA-1280218 Adaptive Immune System
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029481 FCGR activation
R-HSA-2029481 FCGR activation
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-2029485 Role of phospholipids in phagocytosis
R-HSA-2172127 DAP12 interactions
R-HSA-2424491 DAP12 signaling
R-HSA-2454202 Fc epsilon receptor (FCERI) signaling
R-HSA-2454202 Fc epsilon receptor (FCERI) signaling
R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization
R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization
R-HSA-2871796 FCERI mediated MAPK activation
R-HSA-2871809 FCERI mediated Ca+2 mobilization
R-HSA-2871809 FCERI mediated Ca+2 mobilization
R-HSA-354192 Integrin signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-449147 Signaling by Interleukins
R-HSA-451927 Interleukin-2 family signaling
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-5607764 CLEC7A (Dectin-1) signaling
R-HSA-5621480 Dectin-2 family
R-HSA-5621480 Dectin-2 family
R-HSA-5621481 C-type lectin receptors (CLRs)
R-HSA-5621481 C-type lectin receptors (CLRs)
R-HSA-5663205 Infectious disease
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76009 Platelet Aggregation (Plug Formation)
R-HSA-9020558 Interleukin-2 signaling
R-HSA-912631 Regulation of signaling by CBL
R-HSA-912631 Regulation of signaling by CBL
R-HSA-9658195 Leishmania infection
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664323 FCGR3A-mediated IL10 synthesis
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9664433 Leishmania parasite growth and survival
R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
R-HSA-983705 Signaling by the B Cell Receptor (BCR)
R-HSA-983705 Signaling by the B Cell Receptor (BCR)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002382 BXGD000109 Alveolar Bone Loss Musculoskeletal Diseases; Stomatognathic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002880 BXGD000139 Autoimmune hemolytic anemia Immune System Diseases; Hemic and Lymphatic Diseases
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0006840 BXGD000409 Candidiasis Infections
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007107 BXGD000428 Malignant neoplasm of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007130 BXGD000440 Mucinous Adenocarcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008029 BXGD000510 Cherubism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011269 BXGD000710 Dementia, Vascular Nervous System Diseases; Mental Disorders; Cardiovascular Diseases
C0011311 BXGD000714 Dengue Fever Infections
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019187 BXGD001296 Hepatitis, Alcoholic Digestive System Diseases; Chemically-Induced Disorders
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020981 BXGD001474 Angioimmunoblastic Lymphadenopathy Immune System Diseases; Hemic and Lymphatic Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022354 BXGD001540 Jaundice, Obstructive Pathological Conditions, Signs and Symptoms
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023448 BXGD001649 Lymphoid leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024314 BXGD001767 Lymphoproliferative Disorders Immune System Diseases; Hemic and Lymphatic Diseases
C0024419 BXGD001769 Waldenstrom Macroglobulinemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026470 BXGD001903 Monoclonal Gammopathy of Undetermined Significance Immune System Diseases; Hemic and Lymphatic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027830 BXGD002046 neurofibroma Neoplasms; Nervous System Diseases
C0027832 BXGD002048 Neurofibromatosis 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0029443 BXGD002152 Osteomyelitis Infections; Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0040021 BXGD002834 Thromboangiitis Obliterans Cardiovascular Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0042109 BXGD002957 Urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0079218 BXGD003066 Fibromatosis, Aggressive Neoplasms
C0079293 BXGD003069 Epidermolysis Bullosa Acquisita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079774 BXGD003101 Peripheral T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085110 BXGD003126 Severe Combined Immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0162538 BXGD003954 Immunoglobulin A deficiency (disorder) Immune System Diseases; Hemic and Lymphatic Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0221357 BXGD004449 Brachydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0231818 BXGD004526 Airway constriction
C0238013 BXGD004855 Invasive aspergillosis Infections
C0238790 BXGD004956 bone destruction
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242584 BXGD005179 Autoimmune thrombocytopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0242621 BXGD005183 Isochromosomes Pathological Conditions, Signs and Symptoms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262584 BXGD005256 Carcinoma, Small Cell Neoplasms
C0263338 BXGD005290 Chronic urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0265205 BXGD005462 Robinow Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Endocrine System Diseases
C0267797 BXGD005777 Acute hepatitis Digestive System Diseases
C0270850 BXGD006117 Idiopathic generalized epilepsy Nervous System Diseases
C0272286 BXGD006337 Thrombocytopenia due to platelet alloimmunization Hemic and Lymphatic Diseases
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278791 BXGD006587 Chronic lymphocytic leukaemia refractory Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333307 BXGD006946 Superficial ulcer Pathological Conditions, Signs and Symptoms
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0343641 BXGD007636 Human papilloma virus infection Infections
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0347950 BXGD007864 Asthma attack Respiratory Tract Diseases; Immune System Diseases
C0349631 BXGD007938 Richter's syndrome Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0349632 BXGD007939 Splenic Marginal Zone B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376544 BXGD008001 Hematopoietic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0398650 BXGD008212 Immune thrombocytopenic purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0403416 BXGD008282 Idiopathic crescentic glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0403529 BXGD008291 Anti-Glomerular Basement Membrane Disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Respiratory Tract Diseases; Immune System Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0410005 BXGD008407 Nodular fasciitis Neoplasms; Musculoskeletal Diseases; Nervous System Diseases
C0410422 BXGD008426 Chronic multifocal osteomyelitis Infections; Musculoskeletal Diseases
C0521158 BXGD009130 Recurrent tumor
C0521607 BXGD009146 Peritoneal Fibrosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0582415 BXGD009576 Acute asthma Respiratory Tract Diseases; Immune System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0686625 BXGD009836 Secondary malignant neoplasm of lymph nodes of neck
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0853897 BXGD010985 Diabetic Cardiomyopathies Endocrine System Diseases; Cardiovascular Diseases
C0854135 BXGD011002 Pseudomonas aeruginosa infection Infections
C0867389 BXGD011300 Chronic graft-versus-host disease Immune System Diseases
C0877430 BXGD011347 Asthma chronic
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948908 BXGD011564 Nephrotoxic serum nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1136085 BXGD011709 Monoclonal Gammapathies Immune System Diseases; Hemic and Lymphatic Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332078 BXGD012485 Anaplastic large cell lymphoma, ALK negative Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332309 BXGD012521 Anti-Basement Membrane Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1333064 BXGD012587 Classical Hodgkin's Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1861305 BXGD016027 TARSAL-CARPAL COALITION SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2347747 BXGD017040 Adult Classical Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3160909 BXGD018497 Autoimmune arthritis
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3272525 BXGD018623 Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3495917 BXGD019012 Advanced breast cancer
C3539781 BXGD019086 Progressive cGVHD
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3642347 BXGD019246 Basal-Like Breast Carcinoma
C3714514 BXGD019409 Infection Infections
C3828530 BXGD019744 Platelet Component Distribution Width Measurement
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C3887524 BXGD019892 Skin Erosion Skin and Connective Tissue Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4529962 BXGD023178 Fatty Liver Disease
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000332 Fisetin 286.24
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002018 Morin 302.24
BXGC0002071 Apigenin 270.24
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0004580 Carbanilide 212.25
BXGC0004705 Diphenylamine 169.22
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0006193 Ellagic acid 302.19
BXGC0006306 Myricetin 318.24
BXGC0006368 Formic acid 46.03
BXGC0006635 Luteolin 286.24
BXGC0007029 Emodin 270.24
BXGC0012352 Chelerythrine 348.12
BXGC0017933 Sulfuretin 270.05
BXGC0023872 Adenine 135.05
BXGC0024554 D-luciferin 280
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0042870 Piceatannol 244.07
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein