Showing entry for Adult Hepatocellular Carcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006648
Disease NameAdult Hepatocellular Carcinoma
Disease CUI IdC0279607
MeSH Codes C06   C04  
Disease Class NameDigestive System Diseases; Neoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14745 BXGT004090 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 9368 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15169 BXGT004134 Axin-1 8312 reviewed
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 54600 reviewed
O95271 BXGT005369 Poly [ADP-ribose] polymerase tankyrase-1 8658 reviewed
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P0C0S5 BXGT007390 Histone H2A.Z 3015 reviewed
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15907 BXGT008168 Beta-galactoside alpha-2,6-sialyltransferase 1 6480 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24752 BXGT008993 Acetyl-CoA acetyltransferase, mitochondrial 38 reviewed Enzyme
P29508 BXGT009358 Serpin B3 6317 reviewed Enzyme modulator
P32322 BXGT009624 Pyrroline-5-carboxylate reductase 1, mitochondrial 5831 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P53370 BXGT010987 Nucleoside diphosphate-linked moiety X motif 6 11162 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
Q00266 BXGT012515 S-adenosylmethionine synthase isoform type-1 4143 reviewed Enzyme
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q13586 BXGT013380 Stromal interaction molecule 1 6786 reviewed
Q13822 BXGT013396 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5168 reviewed Enzyme
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q16654 BXGT013650 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 5166 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q92993 BXGT019403 Histone acetyltransferase KAT5 10524 reviewed
Q96Q89 BXGT019716 Kinesin-like protein KIF20B 9585 reviewed Cellular structure
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9H5I1 BXGT020480 Histone-lysine N-methyltransferase SUV39H2 79723 reviewed
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 54577 reviewed
Q9ULW0 BXGT021766 Targeting protein for Xklp2 22974 reviewed Cellular structure
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
Q01995 BXGT022678 Transgelin 6876 reviewed Cellular structure
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease