protein

Showing entry for Stromal interaction molecule 1

General Target Information
BXGT Id	BXGT013380
Protein Name	Stromal interaction molecule 1
Uniport Id	Q13586
Gene	STIM1
Gene Id	6786
Domain	SAM_2; SOAR
Pfam	PF07647 PF16533
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
3. Environmental Information Processing	3.2 Signal transduction	hsa04020	Calcium signaling pathway
5. Organismal Systems	5.1 Immune system	hsa04611	Platelet activation

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0032237	activation of store-operated calcium channel activity
Biological Process	GO:0006874	cellular calcium ion homeostasis
Biological Process	GO:0005513	detection of calcium ion
Biological Process	GO:0070166	enamel mineralization
Biological Process	GO:0045762	positive regulation of adenylate cyclase activity
Biological Process	GO:0045766	positive regulation of angiogenesis
Biological Process	GO:0051924	regulation of calcium ion transport
Biological Process	GO:1903779	regulation of cardiac conduction
Biological Process	GO:2001256	regulation of store-operated calcium entry
Biological Process	GO:0002115	store-operated calcium entry
molecular function	GO:0005246	calcium channel regulator activity
molecular function	GO:0005509	calcium ion binding
molecular function	GO:0042802	identical protein binding
molecular function	GO:0051010	microtubule plus-end binding
molecular function	GO:0002020	protease binding
cellular component	GO:0032541	cortical endoplasmic reticulum
cellular component	GO:0005783	endoplasmic reticulum
cellular component	GO:0005789	endoplasmic reticulum membrane
cellular component	GO:0030176	integral component of endoplasmic reticulum membrane
cellular component	GO:0005887	integral component of plasma membrane
cellular component	GO:0005874	microtubule
cellular component	GO:0005886	plasma membrane
cellular component	GO:0044853	plasma membrane raft
cellular component	GO:0033017	sarcoplasmic reticulum membrane

Reactome

Pathway Id	Pathway Name
R-HSA-109582	Hemostasis
R-HSA-1280218	Adaptive Immune System
R-HSA-1280218	Adaptive Immune System
R-HSA-139853	Elevation of cytosolic Ca2+ levels
R-HSA-168256	Immune System
R-HSA-168256	Immune System
R-HSA-397014	Muscle contraction
R-HSA-397014	Muscle contraction
R-HSA-418346	Platelet homeostasis
R-HSA-418360	Platelet calcium homeostasis
R-HSA-5576891	Cardiac conduction
R-HSA-5576891	Cardiac conduction
R-HSA-5578775	Ion homeostasis
R-HSA-5578775	Ion homeostasis
R-HSA-983695	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
R-HSA-983695	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
R-HSA-983705	Signaling by the B Cell Receptor (BCR)
R-HSA-983705	Signaling by the B Cell Receptor (BCR)

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0001339	BXGD000041	Acute pancreatitis	Digestive System Diseases
C0001418	BXGD000050	Adenocarcinoma	Neoplasms
C0001807	BXGD000077	Aggressive behavior	Behavior and Behavior Mechanisms
C0002395	BXGD000111	Alzheimer's Disease	Nervous System Diseases; Mental Disorders
C0002452	BXGD000116	Amelogenesis Imperfecta	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0002871	BXGD000132	Anemia	Hemic and Lymphatic Diseases
C0002880	BXGD000139	Autoimmune hemolytic anemia	Immune System Diseases; Hemic and Lymphatic Diseases
C0003028	BXGD000170	Anhidrosis	Skin and Connective Tissue Diseases
C0003811	BXGD000222	Cardiac Arrhythmia	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850	BXGD000225	Arteriosclerosis	Cardiovascular Diseases
C0003873	BXGD000236	Rheumatoid Arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096	BXGD000252	Asthma	Respiratory Tract Diseases; Immune System Diseases
C0004153	BXGD000260	Atherosclerosis	Cardiovascular Diseases
C0004277	BXGD000266	Tooth Attrition	Stomatognathic Diseases
C0004364	BXGD000270	Autoimmune Diseases	Immune System Diseases
C0005779	BXGD000336	Blood Coagulation Disorders	Hemic and Lymphatic Diseases
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0007131	BXGD000441	Non-Small Cell Lung Carcinoma	Neoplasms; Respiratory Tract Diseases
C0007137	BXGD000445	Squamous cell carcinoma	Neoplasms
C0007847	BXGD000492	Malignant tumor of cervix	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008073	BXGD000518	Developmental Disabilities	Mental Disorders
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0010068	BXGD000648	Coronary heart disease	Cardiovascular Diseases
C0011603	BXGD000734	Dermatitis	Skin and Connective Tissue Diseases
C0011847	BXGD000749	Diabetes	Endocrine System Diseases
C0011849	BXGD000751	Diabetes Mellitus	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854	BXGD000753	Diabetes Mellitus, Insulin-Dependent	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860	BXGD000755	Diabetes Mellitus, Non-Insulin-Dependent	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881	BXGD000760	Diabetic Nephropathy	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013336	BXGD000815	Dwarfism	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013575	BXGD000854	Ectodermal Dysplasia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0014591	BXGD000938	Epistaxis	Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0014877	BXGD000967	Esotropia	Eye Diseases; Nervous System Diseases
C0017636	BXGD001131	Glioblastoma	Neoplasms
C0017638	BXGD001132	Glioma	Neoplasms
C0018801	BXGD001226	Heart failure	Cardiovascular Diseases
C0018802	BXGD001227	Congestive heart failure	Cardiovascular Diseases
C0018817	BXGD001235	Atrial Septal Defects	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018818	BXGD001236	Ventricular Septal Defects	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019693	BXGD001346	HIV Infections	Infections; Immune System Diseases
C0020058	BXGD001355	Howell-Jolly Bodies
C0020534	BXGD001421	Orbital separation excessive	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020538	BXGD001422	Hypertensive disease	Cardiovascular Diseases
C0020598	BXGD001440	Hypocalcemia	Nutritional and Metabolic Diseases
C0020620	BXGD001448	Hypohidrosis	Skin and Connective Tissue Diseases
C0020627	BXGD001453	Hypopharyngeal Neoplasms	Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0020757	BXGD001466	Ichthyoses	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0021051	BXGD001475	Immunologic Deficiency Syndromes	Immune System Diseases
C0021053	BXGD001476	Immune System Diseases	Immune System Diseases
C0023434	BXGD001643	Chronic Lymphocytic Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023473	BXGD001661	Myeloid Leukemia, Chronic	Neoplasms; Hemic and Lymphatic Diseases
C0023896	BXGD001718	Alcoholic Liver Diseases	Digestive System Diseases; Chemically-Induced Disorders
C0024115	BXGD001732	Lung diseases	Respiratory Tract Diseases
C0024121	BXGD001735	Lung Neoplasms	Neoplasms; Respiratory Tract Diseases
C0024314	BXGD001767	Lymphoproliferative Disorders	Immune System Diseases; Hemic and Lymphatic Diseases
C0024623	BXGD001791	Malignant neoplasm of stomach	Digestive System Diseases; Neoplasms
C0025202	BXGD001832	melanoma	Neoplasms
C0026205	BXGD001891	Miosis disorder	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0026764	BXGD001928	Multiple Myeloma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026821	BXGD001933	Muscle Cramp	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026827	BXGD001936	Muscle hypotonia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026837	BXGD001937	Muscle Rigidity	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026848	BXGD001941	Myopathy	Musculoskeletal Diseases; Nervous System Diseases
C0026850	BXGD001942	Muscular Dystrophy	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027051	BXGD001963	Myocardial Infarction	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027092	BXGD001971	Myopia	Eye Diseases
C0027404	BXGD001984	Narcolepsy	Nervous System Diseases; Mental Disorders
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0027654	BXGD002010	Embryonal Neoplasm	Neoplasms
C0027659	BXGD002012	Neoplasms, Experimental	Neoplasms
C0027708	BXGD002025	Nephroblastoma	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027819	BXGD002043	Neuroblastoma	Neoplasms
C0029463	BXGD002160	Osteosarcoma	Neoplasms
C0030305	BXGD002206	Pancreatitis	Digestive System Diseases
C0030552	BXGD002238	Paresis	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0030567	BXGD002240	Parkinson Disease	Nervous System Diseases
C0034150	BXGD002466	Purpura	Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0035021	BXGD002501	Relapsing Fever	Infections
C0035412	BXGD002548	Rhabdomyosarcoma	Neoplasms
C0035869	BXGD002569	Rotavirus Infections	Infections
C0036572	BXGD002625	Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037763	BXGD002699	Spasm	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037822	BXGD002706	Speech Disorders	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038013	BXGD002725	Ankylosing spondylitis	Musculoskeletal Diseases
C0038454	BXGD002760	Cerebrovascular accident	Nervous System Diseases; Cardiovascular Diseases
C0040034	BXGD002836	Thrombocytopenia	Hemic and Lymphatic Diseases
C0041341	BXGD002918	Tuberous Sclerosis	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0042373	BXGD002978	Vascular Diseases	Cardiovascular Diseases
C0042769	BXGD002999	Virus Diseases	Infections
C0079731	BXGD003087	B-Cell Lymphomas	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744	BXGD003090	Diffuse Large B-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085110	BXGD003126	Severe Combined Immunodeficiency	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0085413	BXGD003171	Polycystic Kidney, Autosomal Dominant	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0087031	BXGD003319	Juvenile-Onset Still Disease	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0149931	BXGD003388	Migraine Disorders	Nervous System Diseases
C0151786	BXGD003475	Muscle Weakness	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151854	BXGD003487	Abnormal platelets	Hemic and Lymphatic Diseases
C0153381	BXGD003626	Malignant neoplasm of mouth	Neoplasms; Stomatognathic Diseases
C0153676	BXGD003679	Secondary malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0162309	BXGD003934	Adrenoleukodystrophy	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162871	BXGD003996	Aortic Aneurysm, Abdominal	Cardiovascular Diseases
C0175709	BXGD004013	Centronuclear myopathy	Musculoskeletal Diseases; Nervous System Diseases
C0178874	BXGD004037	Tumor Progression	Pathological Conditions, Signs and Symptoms
C0200665	BXGD004045	Platelet mean volume determination (procedure)
C0200695	BXGD004046	Fetal hemoglobin determination
C0201925	BXGD004058	Calcium measurement
C0206139	BXGD004159	Lichen Planus, Oral	Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0206743	BXGD004285	Rhabdoid Tumor	Neoplasms
C0220611	BXGD004295	Childhood Rhabdomyosarcoma	Neoplasms
C0220641	BXGD004305	Lip and Oral Cavity Carcinoma	Neoplasms; Stomatognathic Diseases
C0221170	BXGD004400	Muscular stiffness	Nervous System Diseases
C0221278	BXGD004435	Anisocytosis
C0221629	BXGD004467	Proximal muscle weakness	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0231528	BXGD004496	Myalgia	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0234958	BXGD004702	Muscle degeneration	Musculoskeletal Diseases
C0235974	BXGD004796	Pancreatic carcinoma	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198	BXGD004893	Gastrointestinal Stromal Tumors	Digestive System Diseases; Neoplasms
C0239676	BXGD004989	High forehead
C0239998	BXGD005012	Recurrent infections	Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0241005	BXGD005072	Creatine phosphokinase serum increased
C0242379	BXGD005157	Malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0265110	BXGD005455	Cerebral Vasospasm	Nervous System Diseases; Cardiovascular Diseases
C0276496	BXGD006426	Familial Alzheimer Disease (FAD)	Nervous System Diseases; Mental Disorders
C0278878	BXGD006609	Adult Glioblastoma	Neoplasms
C0278996	BXGD006621	Malignant Head and Neck Neoplasm	Neoplasms
C0279084	BXGD006626	Kaposi's sarcoma classical type	Neoplasms; Infections
C0279550	BXGD006635	Adult Rhabdomyosarcoma	Neoplasms
C0279606	BXGD006647	Childhood Hepatocellular Carcinoma	Digestive System Diseases; Neoplasms
C0279607	BXGD006648	Adult Hepatocellular Carcinoma	Digestive System Diseases; Neoplasms
C0279626	BXGD006657	Squamous cell carcinoma of esophagus	Digestive System Diseases; Neoplasms
C0279702	BXGD006685	Conventional (Clear Cell) Renal Cell Carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474	BXGD006748	Childhood Glioblastoma	Neoplasms
C0281361	BXGD006774	Adenocarcinoma of pancreas	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0302592	BXGD006851	Cervix carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0344482	BXGD007678	Hypoplasia of corpus callosum	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0344539	BXGD007690	Hypoplasia of iris	Eye Diseases
C0345904	BXGD007745	Malignant neoplasm of liver	Digestive System Diseases; Neoplasms
C0346647	BXGD007832	Malignant neoplasm of pancreas	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349588	BXGD007933	Short stature
C0376358	BXGD007992	Malignant neoplasm of prostate	Neoplasms; Male Urogenital Diseases
C0393576	BXGD008096	Chorea Acanthocytosis Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0410203	BXGD008417	X-linked centronuclear myopathy	Musculoskeletal Diseases; Nervous System Diseases
C0410207	BXGD008419	Tubular Aggregate Myopathy	Musculoskeletal Diseases; Nervous System Diseases
C0410702	BXGD008447	Adolescent idiopathic scoliosis	Musculoskeletal Diseases
C0423224	BXGD008475	Sunken eyes	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0424711	BXGD008541	Orbital separation diminished
C0426415	BXGD008560	Large nose
C0476254	BXGD008984	Dyslexia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0494261	BXGD009023	Combined immunodeficiency	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0497156	BXGD009053	Lymphadenopathy	Hemic and Lymphatic Diseases
C0524620	BXGD009236	Metabolic Syndrome X	Nutritional and Metabolic Diseases
C0524851	BXGD009246	Neurodegenerative Disorders	Nervous System Diseases
C0546264	BXGD009330	Congenital Fiber Type Disproportion	Musculoskeletal Diseases; Nervous System Diseases
C0549629	BXGD009393	Abnormal delivery
C0557874	BXGD009444	Global developmental delay
C0560346	BXGD009475	Difficulty running	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0585442	BXGD009593	Osteosarcoma of bone	Neoplasms
C0596263	BXGD009639	Carcinogenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0600031	BXGD009681	Congenital absence of spleen	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Hemic and Lymphatic Diseases
C0600139	BXGD009695	Prostate carcinoma	Neoplasms; Male Urogenital Diseases
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0699791	BXGD009867	Stomach Carcinoma	Digestive System Diseases; Neoplasms
C0700095	BXGD009875	Central neuroblastoma	Neoplasms; Nervous System Diseases
C0701811	BXGD009902	Poor short-term memory	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0740391	BXGD009987	Middle Cerebral Artery Occlusion	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0752282	BXGD010709	Congenital Structural Myopathy	Musculoskeletal Diseases; Nervous System Diseases
C0850703	BXGD010905	Frequent falls	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0852036	BXGD010934	Pregnancy associated hypertension	Female Urogenital Diseases and Pregnancy Complications; Cardiovascular Diseases
C0878544	BXGD011368	Cardiomyopathies	Cardiovascular Diseases
C0948008	BXGD011499	Ischemic stroke	Nervous System Diseases; Cardiovascular Diseases
C1168401	BXGD011792	Squamous cell carcinoma of the head and neck	Neoplasms
C1269955	BXGD012005	Tumor Cell Invasion
C1303009	BXGD012320	Microcoria, congenital	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1332986	BXGD012574	Childhood Osteosarcoma	Neoplasms
C1333015	BXGD012581	Childhood Kidney Wilms Tumor	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1335302	BXGD012775	Pancreatic Ductal Adenocarcinoma	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1368404	BXGD012899	Hypopharyngeal Carcinoma	Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C1446787	BXGD013085	Cramping sensation quality
C1458140	BXGD013134	Bleeding tendency	Hemic and Lymphatic Diseases
C1458155	BXGD013136	Mammary Neoplasms	Neoplasms; Skin and Connective Tissue Diseases
C1527336	BXGD013271	Sjogren's Syndrome	Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1621958	BXGD013468	Glioblastoma Multiforme	Neoplasms
C1706004	BXGD013569	Anhydrotic Ectodermal Dysplasias	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1708565	BXGD013606	Invasive Cutaneous Melanoma	Neoplasms; Skin and Connective Tissue Diseases
C1720983	BXGD013698	Channelopathies	Pathological Conditions, Signs and Symptoms
C1744558	BXGD013748	T-lymphocyte deficiency
C1832661	BXGD013866	ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1834405	BXGD013970	Nail dysplasia	Pathological Conditions, Signs and Symptoms
C1834536	BXGD013977	Weakness of the intrinsic hand muscles
C1834558	BXGD013978	Myopathy, Centronuclear, Autosomal Dominant	Musculoskeletal Diseases; Nervous System Diseases
C1834696	BXGD013989	Hyporeflexia of lower limbs
C1837098	BXGD014198	Easy fatigability
C1837461	BXGD014234	SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C1837658	BXGD014257	Gross motor development delay	Mental Disorders
C1842170	BXGD014503	Centrally nucleated skeletal muscle fibers
C1843700	BXGD014604	Increased variability in muscle fiber diameter
C1844383	BXGD014628	Recurrent bacterial infection	Infections
C1844820	BXGD014681	Range of joint movement increased
C1846821	BXGD014841	Abnormality of coagulation
C1849667	BXGD015073	Wide nasal base
C1850794	BXGD015178	Proximal amyotrophy
C1850830	BXGD015181	Exercise-induced myalgia	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1854113	BXGD015382	Prominent nasal bridge
C1854494	BXGD015409	Slow progression
C1854882	BXGD015439	Absent speech	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1856694	BXGD015632	Areflexia of lower limbs	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1861324	BXGD016029	Short philtrum
C1861403	BXGD016045	Variable expressivity
C1861451	BXGD016047	Stormorken Syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases; Mental Disorders; Hemic and Lymphatic Diseases
C1864580	BXGD016235	Type 2 muscle fiber atrophy
C1956257	BXGD016623	Pulmonary Stenosis	Cardiovascular Diseases
C1961099	BXGD016672	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2748557	BXGD017597	Immune dysfunction with T-cell inactivation due to calcium entry defect 2	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C2919142	BXGD017867	Short Stature, CTCAE
C2939419	BXGD018178	Secondary Neoplasm	Pathological Conditions, Signs and Symptoms; Neoplasms
C3267073	BXGD018613	Autoinflammatory disease
C3279947	BXGD018789	NAIL DISORDER, NONSYNDROMIC CONGENITAL, 9
C3495559	BXGD018994	Juvenile arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3495676	BXGD019000	Anorectal Malformations	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C3645536	BXGD019247	Autosomal Recessive Centronuclear Myopathy	Musculoskeletal Diseases; Nervous System Diseases
C3661489	BXGD019263	Autosomal Dominant Myotubular Myopathy	Musculoskeletal Diseases; Nervous System Diseases
C3714758	BXGD019431	Juvenile psoriatic arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3714772	BXGD019433	Recurrent fevers
C3828530	BXGD019744	Platelet Component Distribution Width Measurement
C3875321	BXGD019874	Inflammatory dermatosis	Skin and Connective Tissue Diseases
C3887461	BXGD019876	Head and Neck Carcinoma	Neoplasms
C4011726	BXGD020114	MYOPATHY, TUBULAR AGGREGATE, 1	Musculoskeletal Diseases; Nervous System Diseases
C4021024	BXGD020522	Muscle fiber tubular inclusions
C4021280	BXGD020605	Curved 4th toe phalanx
C4021726	BXGD020735	EMG: myopathic abnormalities	Musculoskeletal Diseases; Nervous System Diseases
C4021745	BXGD020752	Abnormality of the musculature
C4022583	BXGD020924	Fatiguable weakness of proximal limb muscles
C4025208	BXGD021591	Severe T-cell immunodeficiency
C4025573	BXGD021672	Increased muscle fatiguability
C4048328	BXGD021903	cervical cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4049446	BXGD021933	Neointimal hyperplasia
C4072904	BXGD022021	Secondary Caesarian section
C4086165	BXGD022126	Childhood Neuroblastoma	Neoplasms
C4551952	BXGD023444	Myopathy, Centronuclear, 1	Musculoskeletal Diseases; Nervous System Diseases
C4552091	BXGD023485	Polyarthritis, Juvenile, Rheumatoid Factor Negative	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4704862	BXGD023681	Polyarthritis, Juvenile, Rheumatoid Factor Positive	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4722085	BXGD023788	Malignant neoplasm of colon and/or rectum
C4751078	BXGD024080	Onychomatricoma	Neoplasms

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002586	Calcium		40.08

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}