Showing entry for Squamous cell carcinoma of oropharynx


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006737
Disease NameSquamous cell carcinoma of oropharynx
Disease CUI IdC0280313
MeSH Codes C04   C07   C09  
Disease Class NameNeoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0001574   HP:0002664  
Human Phenotype Ontology TermAbnormality of the integument; Neoplasm
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O14744 BXGT004089 Protein arginine N-methyltransferase 5 10419 reviewed Epigenetic regulator
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P14625 BXGT008029 Endoplasmin 7184 reviewed Chaperone
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P16070 BXGT008186 CD44 antigen 960 reviewed
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25311 BXGT009036 Zinc-alpha-2-glycoprotein 563 reviewed
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31025 BXGT009500 Lipocalin-1 3933 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31947 BXGT009589 14-3-3 protein sigma 2810 reviewed Chaperone
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P47736 BXGT010579 Rap1 GTPase-activating protein 1 5909 reviewed Enzyme modulator
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P55055 BXGT011101 Oxysterols receptor LXR-beta 7376 reviewed Nuclear receptor
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P57735 BXGT011214 Ras-related protein Rab-25 57111 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01831 BXGT012621 DNA repair protein complementing XP-C cells 7508 reviewed Nucleic acid binding
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15131 BXGT013545 Cyclin-dependent kinase 10 8558 reviewed Kinase
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q53EZ4 BXGT015010 Centrosomal protein of 55 kDa 55165 reviewed
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q96D31 BXGT019635 Calcium release-activated calcium channel protein 1 84876 reviewed Ion channel
Q96EP1 BXGT019651 E3 ubiquitin-protein ligase CHFR 55743 reviewed Enzyme
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZJ5 BXGT021275 Eukaryotic translation initiation factor 2-alpha kinase 3 9451 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9Y3B4 BXGT022255 Splicing factor 3B subunit 6 51639 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
Q9NZM1 BXGT023948 Myoferlin 26509 reviewed Transporter
Q9BYE2 BXGT024631 Transmembrane protease serine 13 84000 reviewed Enzyme
P28715 BXGT025675 DNA repair protein complementing XP-G cells 2073 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease