Showing entry for Eukaryotic translation initiation factor 2-alpha kinase 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021275
Protein NameEukaryotic translation initiation factor 2-alpha kinase 3
Uniport IdQ9NZJ5
GeneEIF2AK3
Gene Id9451
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
4. Cellular Processes 4.1 Transport and catabolism hsa04140 Autophagy - animal
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
4. Cellular Processes 4.2 Cell growth and death hsa04210 Apoptosis
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04932 Non-alcoholic fatty liver disease (NAFLD)
6. Human Diseases 6.4 Neurodegenerative diseases hsa05010 Alzheimer disease
6. Human Diseases 6.9 Infectious diseases: Viral hsa05160 Hepatitis C
6. Human Diseases 6.9 Infectious diseases: Viral hsa05162 Measles
6. Human Diseases 6.9 Infectious diseases: Viral hsa05168 Herpes simplex virus 1 infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0001525 angiogenesis
Biological Process GO:0030282 bone mineralization
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0034198 cellular response to amino acid starvation
Biological Process GO:0070417 cellular response to cold
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0002063 chondrocyte development
Biological Process GO:0036492 eiF2alpha phosphorylation in response to endoplasmic reticulum stress
Biological Process GO:0031018 endocrine pancreas development
Biological Process GO:0007029 endoplasmic reticulum organization
Biological Process GO:0030968 endoplasmic reticulum unfolded protein response
Biological Process GO:0006983 ER overload response
Biological Process GO:0048009 insulin-like growth factor receptor signaling pathway
Biological Process GO:0031642 negative regulation of myelination
Biological Process GO:0017148 negative regulation of translation
Biological Process GO:0032057 negative regulation of translational initiation in response to stress
Biological Process GO:0001503 ossification
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0036499 PERK-mediated unfolded protein response
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:1900182 positive regulation of protein localization to nucleus
Biological Process GO:0045943 positive regulation of transcription by RNA polymerase I
Biological Process GO:0010575 positive regulation of vascular endothelial growth factor production
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
Biological Process GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Biological Process GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation
Biological Process GO:0034976 response to endoplasmic reticulum stress
Biological Process GO:1990737 response to manganese-induced endoplasmic reticulum stress
Biological Process GO:0001501 skeletal system development
molecular function GO:0005524 ATP binding
molecular function GO:0019899 enzyme binding
molecular function GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity
molecular function GO:0051879 Hsp90 protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0022626 cytosolic ribosome
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0030176 integral component of endoplasmic reticulum membrane
cellular component GO:0016020 membrane
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-381042 PERK regulates gene expression
R-HSA-381119 Unfolded Protein Response (UPR)
R-HSA-392499 Metabolism of proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009421 BXGD000608 Comatose Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011311 BXGD000714 Dengue Fever Infections
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016514 BXGD001066 Foot-and-Mouth Disease Infections; Animal Diseases
C0017160 BXGD001099 Gastroenteritis Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017979 BXGD001159 Glycosuria Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018798 BXGD001223 Congenital Heart Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020490 BXGD001403 Hyperopia Eye Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0021192 BXGD001490 Indeterminate leprosy Infections; Skin and Connective Tissue Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0022638 BXGD001567 Ketosis Nutritional and Metabolic Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022821 BXGD001590 Kyphosis deformity of spine Musculoskeletal Diseases
C0023348 BXGD001636 Leprosy, Lepromatous Infections
C0024003 BXGD001726 Lordosis Musculoskeletal Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024814 BXGD001809 Marinesco-Sjogren syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026760 BXGD001927 Multiple Epiphyseal Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026826 BXGD001935 Muscle Hypertonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0029172 BXGD002120 Oral Submucous Fibrosis Stomatognathic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029422 BXGD002142 Osteochondrodysplasias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0029434 BXGD002146 Osteogenesis Imperfecta Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038238 BXGD002741 Steatorrhea Digestive System Diseases; Nutritional and Metabolic Diseases
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042834 BXGD003004 Vital capacity
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151516 BXGD003430 Thyroid Hypoplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151747 BXGD003471 Renal tubular disorder Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0153594 BXGD003669 Malignant neoplasm of testis Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C0158981 BXGD003914 Neonatal diabetes mellitus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162557 BXGD003956 Liver Failure, Acute Digestive System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206608 BXGD004184 Flavivirus Infections Infections
C0221357 BXGD004449 Brachydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0231557 BXGD004500 Abnormal bone formation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0239137 BXGD004965 Coxa valga Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0239676 BXGD004989 High forehead
C0240340 BXGD005031 Microdontia (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0242363 BXGD005156 Islet Cell Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0263313 BXGD005285 Pemphigus Foliaceus Skin and Connective Tissue Diseases; Immune System Diseases
C0264172 BXGD005371 Barrel chest Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266267 BXGD005638 Congenital hypoplasia of pancreas Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266610 BXGD005699 Preauricular dimple Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0267963 BXGD005796 Exocrine pancreatic insufficiency Digestive System Diseases
C0270823 BXGD006112 Petit mal status Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0276496 BXGD006426 Familial Alzheimer Disease (FAD) Nervous System Diseases; Mental Disorders
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280313 BXGD006737 Squamous cell carcinoma of oropharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0311335 BXGD006877 Grand Mal Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0342153 BXGD007436 Congenital thyroid hypoplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0342273 BXGD007448 Transient neonatal diabetes mellitus
C0342276 BXGD007449 Maturity onset diabetes mellitus in young Nutritional and Metabolic Diseases; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0362046 BXGD007959 Prediabetes syndrome Nutritional and Metabolic Diseases; Endocrine System Diseases
C0392476 BXGD008046 Epiphyseal dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0393734 BXGD008131 Complex Partial Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0410528 BXGD008430 Skeletal dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0423109 BXGD008470 Upward slant of palpebral fissure
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0426789 BXGD008576 Short thorax
C0432217 BXGD008740 Wolcott-Rallison syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Immune System Diseases; Endocrine System Diseases
C0432355 BXGD008780 Hypoplasia of nipple
C0489786 BXGD009018 Height
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0541764 BXGD009259 Delayed bone age
C0557874 BXGD009444 Global developmental delay
C0575081 BXGD009512 Gait abnormality Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0576093 BXGD009525 Knee joint valgus deformity Musculoskeletal Diseases
C0578038 BXGD009542 Thin lips
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C0740447 BXGD009998 Diabetic peripheral neuropathy Nervous System Diseases; Endocrine System Diseases
C0751522 BXGD010488 Status Epilepticus, Subclinical Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751523 BXGD010489 Non-Convulsive Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751524 BXGD010490 Simple Partial Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0854110 BXGD011000 Insulin-resistant diabetes mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0855197 BXGD011079 Malignant Testicular Germ Cell Tumor Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C0860659 BXGD011240 Aloof
C0878659 BXGD011380 Disproportionate short stature Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1262477 BXGD011882 Weight decreased Pathological Conditions, Signs and Symptoms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1337011 BXGD012874 Well Differentiated Pancreatic Endocrine Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1691215 BXGD013491 Penile hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1833104 BXGD013896 DIABETES MELLITUS, PERMANENT NEONATAL Nutritional and Metabolic Diseases; Endocrine System Diseases
C1835884 BXGD014061 Triangular face
C1836542 BXGD014129 Depressed nasal bridge
C1836688 BXGD014149 Narrow iliac wings
C1837246 BXGD014208 Intracerebral periventricular calcifications
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1842153 BXGD014499 Irregular vertebral endplates
C1844704 BXGD014665 Platyspondyly
C1846439 BXGD014817 Hypoplasia of the odontoid process Musculoskeletal Diseases
C1846803 BXGD014840 Small epiphyses
C1848701 BXGD014967 Elevated hepatic transaminase
C1854301 BXGD015391 Motor delay Mental Disorders
C1856904 BXGD015654 Reduced pancreatic beta cells
C1856912 BXGD015656 Shortening of all middle phalanges of the fingers
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1857527 BXGD015714 Flattened epiphysis
C1857651 BXGD015730 Ivory epiphyses of the phalanges of the hand
C1858430 BXGD015792 Death in infancy
C1859480 BXGD015899 Cone-shaped epiphyses of the phalanges of the hand
C1861453 BXGD016049 Pseudohyperkalemia Cardiff Nutritional and Metabolic Diseases
C1863749 BXGD016195 Carpal bone hypoplasia
C1865343 BXGD016316 OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT OF SPINE Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363774 BXGD017105 Neutrophilic asthma
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C2936476 BXGD018123 Chronic Liver Failure Digestive System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714514 BXGD019409 Infection Infections
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3805574 BXGD019481 Increased fracture rate
C3826457 BXGD019724 Diabetes in children
C3887551 BXGD019898 Memory dysfunction Mental Disorders
C3887641 BXGD019909 Recurrent hepatitis Digestive System Diseases
C4020962 BXGD020512 Enlarged thorax
C4021554 BXGD020670 Irregular tarsal ossification
C4023991 BXGD021284 Ivory epiphyses of the toes
C4025401 BXGD021658 Irregular carpal bones
C4025814 BXGD021806 Abnormality of the metaphysis
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4321446 BXGD022751 K ATP Permanent Neonatal Diabetes
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551647 BXGD023381 Long QT Syndrome 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4551862 BXGD023429 Ophthalmoplegia, Progressive Supranuclear Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4551863 BXGD023430 Supranuclear Palsy, Progressive, 1 Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4551915 BXGD023441 Gait Disturbance, CTCAE
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000696 Tartaric acid 150.09
BXGC0016470 Camptothecin 348.11
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein