Showing entry for Primary central nervous system lymphoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006766
Disease NamePrimary central nervous system lymphoma
Disease CUI IdC0280803
MeSH Codes C04   C20   C10   C15  
Disease Class NameNeoplasms; Immune System Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0002664   HP:0001871  
Human Phenotype Ontology TermNeoplasm; Abnormality of blood and blood-forming tissues
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O43612 BXGT004605 Orexin 3060 reviewed
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P04424 BXGT006214 Argininosuccinate lyase 435 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11912 BXGT007758 B-cell antigen receptor complex-associated protein alpha chain 973 reviewed Receptor
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P19113 BXGT008458 Histidine decarboxylase 3067 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20062 BXGT008543 Transcobalamin-2 6948 reviewed
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P41440 BXGT010261 Folate transporter 1 6573 reviewed Transporter
P42226 BXGT010288 Signal transducer and activator of transcription 6 6778 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P51858 BXGT010900 Hepatoma-derived growth factor 3068 reviewed Signaling
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P60903 BXGT011339 Protein S100-A10 6281 reviewed Calcium-binding protein
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 7301 reviewed Kinase
Q13541 BXGT013371 Eukaryotic translation initiation factor 4E-binding protein 1 1978 reviewed Nucleic acid binding
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15262 BXGT013555 Receptor-type tyrosine-protein phosphatase kappa 5796 reviewed Enzyme
Q15349 BXGT013558 Ribosomal protein S6 kinase alpha-2 6196 reviewed Kinase
Q15418 BXGT013569 Ribosomal protein S6 kinase alpha-1 6195 reviewed Kinase
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q8TCG1 BXGT018797 Protein CIP2A 57650 reviewed
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96RG2 BXGT019726 PAS domain-containing serine/threonine-protein kinase 23178 reviewed Kinase
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BXL7 BXGT020171 Caspase recruitment domain-containing protein 11 84433 reviewed
Q9BZR6 BXGT020202 Reticulon-4 receptor 65078 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UDY8 BXGT021670 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 10892 reviewed Enzyme
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
P35251 BXGT025853 Replication factor C subunit 1 5981 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease