Showing entry for Ribosomal protein S6 kinase alpha-3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010893
Protein NameRibosomal protein S6 kinase alpha-3
Uniport IdP51812
GeneRPS6KA3
Gene Id6197
DomainPkinase; Pkinase_C
Pfam PF00069   PF00433  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
4. Cellular Processes 4.2 Cell growth and death hsa04114 Oocyte meiosis
3. Environmental Information Processing 3.2 Signal transduction hsa04150 mTOR signaling pathway
5. Organismal Systems 5.10 Environmental adaptation hsa04714 Thermogenesis
5. Organismal Systems 5.6 Nervous system hsa04720 Long-term potentiation
5. Organismal Systems 5.6 Nervous system hsa04722 Neurotrophin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04914 Progesterone-mediated oocyte maturation
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04931 Insulin resistance
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007049 cell cycle
Biological Process GO:0007417 central nervous system development
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0045597 positive regulation of cell differentiation
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0043620 regulation of DNA-templated transcription in response to stress
Biological Process GO:0043555 regulation of translation in response to stress
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0007165 signal transduction
Biological Process GO:0001501 skeletal system development
Biological Process GO:0002224 toll-like receptor signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
molecular function GO:0000287 magnesium ion binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0004711 ribosomal protein S6 kinase activity
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-112316 Neuronal System
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane
R-HSA-166166 MyD88-independent TLR4 cascade
R-HSA-166520 Signaling by NTRKs
R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade
R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade
R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade
R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade
R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade
R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168898 Toll-like Receptor Cascades
R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade
R-HSA-187037 Signaling by NTRK1 (TRKA)
R-HSA-198725 Nuclear Events (kinase and transcription factor activation)
R-HSA-198753 ERK/MAPK targets
R-HSA-199920 CREB phosphorylation
R-HSA-2262752 Cellular responses to stress
R-HSA-2262752 Cellular responses to stress
R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP)
R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP)
R-HSA-2559583 Cellular Senescence
R-HSA-2559583 Cellular Senescence
R-HSA-372790 Signaling by GPCR
R-HSA-373760 L1CAM interactions
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-422475 Axon guidance
R-HSA-437239 Recycling pathway of L1
R-HSA-438064 Post NMDA receptor activation events
R-HSA-438064 Post NMDA receptor activation events
R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-444257 RSK activation
R-HSA-444257 RSK activation
R-HSA-448424 Interleukin-17 signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases
R-HSA-450294 MAP kinase activation
R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling
R-HSA-9675108 Nervous system development
R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
R-HSA-975155 MyD88 dependent cascade initiated on endosome
R-HSA-975871 MyD88 cascade initiated on plasma membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001125 BXGD000024 Acidosis, Lactic Nutritional and Metabolic Diseases
C0002382 BXGD000109 Alveolar Bone Loss Musculoskeletal Diseases; Stomatognathic Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005941 BXGD000353 Bone Diseases, Developmental Musculoskeletal Diseases
C0005967 BXGD000357 Bone neoplasms Neoplasms; Musculoskeletal Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009952 BXGD000639 Febrile Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0010495 BXGD000674 Cutis Laxa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0011269 BXGD000710 Dementia, Vascular Nervous System Diseases; Mental Disorders; Cardiovascular Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013132 BXGD000799 Drooling Stomatognathic Diseases
C0013238 BXGD000806 Dry Eye Syndromes Eye Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015469 BXGD000996 Facial paralysis Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Stomatognathic Diseases
C0016034 BXGD001034 Breast Fibrocystic Disease Skin and Connective Tissue Diseases
C0016202 BXGD001050 Flatfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0016842 BXGD001083 Congenital pectus excavatum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018524 BXGD001200 Hallucinations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018818 BXGD001236 Ventricular Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019294 BXGD001314 Hernia, Inguinal Pathological Conditions, Signs and Symptoms
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020608 BXGD001443 Hypodontia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0022821 BXGD001590 Kyphosis deformity of spine Musculoskeletal Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024433 BXGD001771 Macrostomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0024636 BXGD001793 Malocclusion Stomatognathic Diseases
C0024790 BXGD001804 Paroxysmal nocturnal hemoglobinuria Hemic and Lymphatic Diseases
C0024894 BXGD001810 Mastitis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C0025037 BXGD001822 Meckel Diverticulum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026266 BXGD001895 Mitral Valve Insufficiency Cardiovascular Diseases
C0026267 BXGD001896 Mitral Valve Prolapse Syndrome Cardiovascular Diseases
C0026351 BXGD001900 Moderate intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027626 BXGD002005 Neoplasm Invasiveness Pathological Conditions, Signs and Symptoms; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028326 BXGD002075 Noonan Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028949 BXGD002100 Oligomenorrhea Pathological Conditions, Signs and Symptoms
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033922 BXGD002440 Psychomotor Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0034194 BXGD002472 Pyloric Stenosis Digestive System Diseases
C0034888 BXGD002492 Rectal Prolapse Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0034935 BXGD002497 Babinski Reflex
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0036916 BXGD002643 Sexually Transmitted Diseases Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0037315 BXGD002687 Sleep Apnea Syndromes Respiratory Tract Diseases; Nervous System Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0040147 BXGD002847 Thyroiditis Endocrine System Diseases
C0040427 BXGD002864 Tooth Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0040433 BXGD002865 Tooth Crowding Stomatognathic Diseases
C0042024 BXGD002949 Urinary Incontinence Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042140 BXGD002963 Uterine Prolapse Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0042420 BXGD002982 Vasovagal syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042870 BXGD003008 Vitamin D Deficiency Nutritional and Metabolic Diseases
C0043119 BXGD003029 Werner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0079680 BXGD003085 Lentivirus Infections Infections
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085271 BXGD003148 Self-Injurious Behavior Behavior and Behavior Mechanisms
C0086025 BXGD003262 Codependency Behavior and Behavior Mechanisms
C0086437 BXGD003282 Joint laxity Musculoskeletal Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0158731 BXGD003902 Congenital pectus carinatum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0221347 BXGD004442 Acrocyanosis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Respiratory Tract Diseases; Cardiovascular Diseases
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0221357 BXGD004449 Brachydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221358 BXGD004450 Long narrow head
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0235991 BXGD004802 Small for gestational age (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0238462 BXGD004937 Medullary carcinoma of thyroid Neoplasms; Endocrine System Diseases
C0239137 BXGD004965 Coxa valga Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0239174 BXGD004969 Late tooth eruption
C0239234 BXGD004974 Low set ears
C0240310 BXGD005030 Hypoplasia of the maxilla
C0240379 BXGD005033 Open mouth (finding)
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242510 BXGD005173 Drug usage Chemically-Induced Disorders; Mental Disorders
C0242596 BXGD005181 Neoplasm, Residual Pathological Conditions, Signs and Symptoms; Neoplasms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263401 BXGD005298 Cutis marmorata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases; Cardiovascular Diseases; Wounds and Injuries
C0264142 BXGD005368 Spade-like hand Musculoskeletal Diseases
C0265252 BXGD005483 Coffin-Lowry syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0265253 BXGD005484 Stickler syndrome (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases
C0266054 BXGD005615 Premature tooth eruption
C0277959 BXGD006487 Coarse hair
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0280803 BXGD006766 Primary central nervous system lymphoma Neoplasms; Immune System Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0281267 BXGD006770 bilateral breast cancer Neoplasms; Skin and Connective Tissue Diseases
C0302511 BXGD006849 Small for gestational age fetus Pathological Conditions, Signs and Symptoms
C0314719 BXGD006890 Dryness of eye Eye Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0343084 BXGD007600 Capillary Leak Syndrome Cardiovascular Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345392 BXGD007732 Congenital kyphoscoliosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346957 BXGD007836 Disseminated Malignant Neoplasm Neoplasms
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376544 BXGD008001 Hematopoietic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0392188 BXGD008036 Abnormal rapid eye movement sleep Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0399352 BXGD008236 Developmental absence of tooth Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0399526 BXGD008251 Class III malocclusion Stomatognathic Diseases
C0423110 BXGD008471 Downward slant of palpebral fissure
C0423113 BXGD008473 Telecanthus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0424230 BXGD008522 Motor retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424731 BXGD008542 Single transverse palmar crease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0426421 BXGD008561 Wide nose
C0426429 BXGD008564 Broad nasal tip
C0426870 BXGD008592 Large hand
C0426886 BXGD008594 Tapering fingers (finding)
C0432072 BXGD008718 Dysmorphic features
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0494475 BXGD009030 Tonic - clonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0541764 BXGD009259 Delayed bone age
C0541794 BXGD009262 Skeletal muscle atrophy
C0557874 BXGD009444 Global developmental delay
C0575081 BXGD009512 Gait abnormality Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0575158 BXGD009515 Kyphoscoliosis deformity of spine Musculoskeletal Diseases
C0576225 BXGD009526 Long foot Musculoskeletal Diseases
C0581342 BXGD009560 Redundant skin Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600033 BXGD009682 Acquired Kyphoscoliosis Musculoskeletal Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0678255 BXGD009752 polydrug use
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0749379 BXGD010214 Thoracolumbar scoliosis Musculoskeletal Diseases
C0751456 BXGD010448 Developmental Psychomotor Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0796225 BXGD010818 Mental Retardation, X-Linked 19 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0856975 BXGD011127 Autistic behavior Behavior and Behavior Mechanisms
C1096086 BXGD011601 Deformity of lower limb
C1136249 BXGD011715 Mental Retardation, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1176475 BXGD011798 Ductal Carcinoma Neoplasms
C1262477 BXGD011882 Weight decreased Pathological Conditions, Signs and Symptoms
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1398312 BXGD012999 Narrow palate
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1527349 BXGD013277 Ductal Breast Carcinoma Neoplasms
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1737329 BXGD013728 Dysmorphism Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1835884 BXGD014061 Triangular face
C1836542 BXGD014129 Depressed nasal bridge
C1836543 BXGD014130 Thick vermilion border
C1836688 BXGD014149 Narrow iliac wings
C1837084 BXGD014195 Short metacarpal
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1837260 BXGD014214 Prominent forehead
C1837397 BXGD014227 Severe global developmental delay
C1837404 BXGD014229 High, narrow palate
C1839326 BXGD014367 Abnormal form of the vertebral bodies
C1839739 BXGD014400 Thick lower lip vermilion
C1839797 BXGD014409 Deep philtrum
C1839829 BXGD014413 Short distal phalanx of finger
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1840077 BXGD014434 Anteverted nostril
C1842060 BXGD014491 Prominent supraorbital ridges
C1842366 BXGD014512 Low anterior hairline
C1844577 BXGD014647 Hyperextensibility of the finger joints
C1844809 BXGD014677 Thick nasal alae
C1844810 BXGD014678 Thick nasal septum
C1844813 BXGD014679 Widely spaced teeth
C1844818 BXGD014680 Lumbar kyphosis
C1844822 BXGD014682 Drumstick terminal phalanges
C1844825 BXGD014683 Hyperconvex fingernails
C1844906 BXGD014692 Broad finger
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C1846151 BXGD014787 Widened subarachnoid space
C1847879 BXGD014895 X-linked dominant inheritance
C1848207 BXGD014916 Poor speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1849340 BXGD015039 Long palpebral fissure
C1850601 BXGD015159 Abnormality of brainstem morphology
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1853237 BXGD015319 Isolated cases
C1853242 BXGD015322 Midface retrusion
C1853246 BXGD015323 Eversion of lower lip
C1853487 BXGD015340 Thick eyebrow
C1854114 BXGD015383 Short nose
C1854301 BXGD015391 Motor delay Mental Disorders
C1855285 BXGD015483 Protruding ear
C1855728 BXGD015536 Low posterior hairline
C1856786 BXGD015645 Hypoplastic fingernail
C1858036 BXGD015763 Periorbital fullness
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1858452 BXGD015796 Thickened calvaria
C1859520 BXGD015907 Progressive spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1860253 BXGD015974 Pseudoepiphyses of the metacarpals
C1861866 BXGD016087 Aplasia/Hypoplasia of the corpus callosum
C1862475 BXGD016132 Abnormality of retinal pigmentation
C1865014 BXGD016282 Long philtrum
C1865017 BXGD016283 Thin upper lip vermilion
C1868085 BXGD016486 Craniofacial hyperostosis
C1868571 BXGD016508 Highly arched eyebrow
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C2020284 BXGD016881 Stickler syndrome, type 1 Pathological Conditions, Signs and Symptoms; Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2243051 BXGD017008 Large head (disorder)
C2674608 BXGD017250 Feeding difficulties in infancy
C2700438 BXGD017469 MAJOR AFFECTIVE DISORDER 7 Mental Disorders
C2700439 BXGD017470 MAJOR AFFECTIVE DISORDER 8 Mental Disorders
C2700440 BXGD017471 MAJOR AFFECTIVE DISORDER 9 Mental Disorders
C2919142 BXGD017867 Short Stature, CTCAE
C2931498 BXGD018030 Mental Retardation, X-Linked 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2931507 BXGD018032 Sternal cleft Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3161330 BXGD018511 Profound intellectual disabilities Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3164445 BXGD018529 Abnormality of aortic valve
C3278923 BXGD018748 Dilated ventricles (finding)
C3279222 BXGD018751 Aplasia/Hypoplasia of the cerebellum
C3495439 BXGD018986 Inflammatory disorder of breast Skin and Connective Tissue Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3553764 BXGD019187 Joint hyperflexibility
C3642347 BXGD019246 Basal-Like Breast Carcinoma
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3840083 BXGD019793 Late closure of anterior fontanel
C4021538 BXGD020660 Mild neurosensory hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C4021608 BXGD020695 Shortening of all distal phalanges of the fingers
C4021620 BXGD020699 Clinodactyly of the 2nd toe
C4021787 BXGD020780 Abnormal diaphysis morphology
C4021804 BXGD020793 Abnormality of the nasal alae
C4022012 BXGD020868 Death in early adulthood
C4022728 BXGD020968 Abnormal upper to lower segment ratio
C4022964 BXGD021046 Abnormality of the occipital bone
C4023791 BXGD021262 Abnormality of the clivus
C4024664 BXGD021362 Moderate sensorineural hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C4025753 BXGD021777 Abnormal tricuspid valve morphology
C4025759 BXGD021780 Abnormal mitral valve morphology
C4025790 BXGD021791 Specific learning disability
C4049796 BXGD021951 Abnormality of cardiovascular system morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4082304 BXGD022090 Oligodontia
C4083076 BXGD022104 Increased head circumference
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4316903 BXGD022711 Absence Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4317146 BXGD022730 Acid reflux
C4551485 BXGD023312 Clinodactyly
C4551570 BXGD023357 2-3 toe syndactyly
C4551583 BXGD023361 Cerebral cortical atrophy
C4551915 BXGD023441 Gait Disturbance, CTCAE
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4725671 BXGD023833 High-Risk Neuroblastoma Neoplasms
C4733092 BXGD023907 estrogen receptor-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000655 Harmalol 200.24
BXGC0000933 (-)-Arctigenin 372.41
BXGC0001544 Harmaline 214.26
BXGC0001545 Harmine 212.25
BXGC0001940 Daphnetin 178.14
BXGC0002071 Apigenin 270.24
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0007014 Harman 182.22
BXGC0007052 Olomoucine 298.34
BXGC0012352 Chelerythrine 348.12
BXGC0012706 4-hydroxy-5-nitrophenyl acetic acid 197.03
BXGC0013109 4-[2-(3,5-Dihydroxyphenyl)Ethenyl]Benzene-1,2-Diol 244.07
BXGC0013582 Curcumin 368.13
BXGC0020911 Debromohymenialdisine 245.09
BXGC0024554 D-luciferin 280
BXGC0034256 Rottlerin 516.18
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0042870 Piceatannol 244.07
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
BXGC0051873 Sl-0101 516.13
BXGC0051995 Wedelolactone 314.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein