adisease

Showing entry for Skin carcinoma

General Disease Information
BXGD Id	BXGD009871
Disease Name	Skin carcinoma
Disease CUI Id	C0699893
MeSH Codes	C04 C17
Disease Class Name	Neoplasms; Skin and Connective Tissue Diseases
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0001574 HP:0002664
Human Phenotype Ontology Term	Abnormality of the integument; Neoplasm
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O15217	BXGT004137	Glutathione S-transferase A4	2941	reviewed
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P21709	BXGT008685	Ephrin type-A receptor 1	2041	reviewed	Kinase
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25021	BXGT009004	Histamine H2 receptor	3274	reviewed	G-protein coupled receptor
P25105	BXGT009021	Platelet-activating factor receptor	5724	reviewed	G-protein coupled receptor
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P29373	BXGT009337	Cellular retinoic acid-binding protein 2	1382	reviewed
P30304	BXGT009418	M-phase inducer phosphatase 1	993	reviewed	Enzyme
P30305	BXGT009419	M-phase inducer phosphatase 2	994	reviewed	Enzyme
P30307	BXGT009421	M-phase inducer phosphatase 3	995	reviewed	Enzyme
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P36969	BXGT009949	Phospholipid hydroperoxide glutathione peroxidase	2879	reviewed	Enzyme
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P42226	BXGT010288	Signal transducer and activator of transcription 6	6778	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42357	BXGT010306	Histidine ammonia-lyase	3034	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P50120	BXGT010773	Retinol-binding protein 2	5948	reviewed
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P55055	BXGT011101	Oxysterols receptor LXR-beta	7376	reviewed	Nuclear receptor
P55899	BXGT011131	IgG receptor FcRn large subunit p51	2217	reviewed
P55957	BXGT011137	BH3-interacting domain death agonist	637	reviewed
P59768	BXGT011277	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	54331	reviewed	Enzyme modulator
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q01726	BXGT012610	Melanocyte-stimulating hormone receptor	4157	reviewed	G-protein coupled receptor
Q01831	BXGT012621	DNA repair protein complementing XP-C cells	7508	reviewed	Nucleic acid binding
Q03468	BXGT012716	DNA excision repair protein ERCC-6	2074	reviewed
Q05823	BXGT012840	2-5A-dependent ribonuclease	6041	reviewed	Kinase
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q92876	BXGT019388	Kallikrein-6	5653	reviewed	Enzyme
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9ULJ6	BXGT021761	Zinc finger MIZ domain-containing protein 1	57178	reviewed
Q9Y256	BXGT022217	CAAX prenyl protease 2	9986	reviewed	Enzyme
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q59FF6	BXGT023693	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	2074	unreviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}