Showing entry for Brain Tumor, Primary


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD010270
Disease NameBrain Tumor, Primary
Disease CUI IdC0750974
MeSH Codes C04   C10  
Disease Class NameNeoplasms; Nervous System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14786 BXGT004099 Neuropilin-1 8829 reviewed
O15164 BXGT004133 Transcription intermediary factor 1-alpha 8805 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P46940 BXGT010556 Ras GTPase-activating-like protein IQGAP1 8826 reviewed Enzyme modulator
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P50225 BXGT010781 Sulfotransferase 1A1 6817 reviewed
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P78325 BXGT011832 Disintegrin and metalloproteinase domain-containing protein 8 101 reviewed Enzyme
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q8N3R9 BXGT018507 MAGUK p55 subfamily member 5 64398 reviewed Enzyme
Q8NCD3 BXGT018547 Holliday junction recognition protein 55355 reviewed
Q92698 BXGT019362 DNA repair and recombination protein RAD54-like 8438 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q99835 BXGT019969 Smoothened homolog 6608 reviewed G-protein coupled receptor
Q9UBK8 BXGT021655 Methionine synthase reductase 4552 reviewed
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q13029 BXGT022688 PR domain zinc finger protein 2 7799 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
Q96AE4 BXGT025980 Far upstream element-binding protein 1 8880 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease