adisease

Showing entry for Cerebral Ischemia

General Disease Information
BXGD Id	BXGD011409
Disease Name	Cerebral Ischemia
Disease CUI Id	C0917798
MeSH Codes	C10 C14
Disease Class Name	Nervous System Diseases; Cardiovascular Diseases
Semantic Type	Pathologic Function
Human Phenotype Ontology Id	HP:0000707 HP:0001626
Human Phenotype Ontology Term	Abnormality of the nervous system; Abnormality of the cardiovascular system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	1128	reviewed	G-protein coupled receptor
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P17676	BXGT008327	CCAAT/enhancer-binding protein beta	1051	reviewed	Transcription factor
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P25963	BXGT009080	NF-kappa-B inhibitor alpha	4792	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P55211	BXGT011111	Caspase-9	842	reviewed	Enzyme
P99999	BXGT012235	Cytochrome c	54205	reviewed
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q08334	BXGT012981	Interleukin-10 receptor subunit beta	3588	reviewed	Receptor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q8N159	BXGT018496	N-acetylglutamate synthase, mitochondrial	162417	reviewed
Q96F46	BXGT019656	Interleukin-17 receptor A	23765	reviewed
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9BXH1	BXGT020167	Bcl-2-binding component 3	27113	reviewed
Q9NR28	BXGT021178	Diablo homolog, mitochondrial	56616	reviewed
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P63167	BXGT024120	Dynein light chain 1, cytoplasmic	8655	reviewed	Cellular structure
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}