Showing entry for Oropharyngeal Carcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD017065
Disease NameOropharyngeal Carcinoma
Disease CUI IdC2349952
MeSH Codes C04   C07   C09  
Disease Class NameNeoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O15075 BXGT004124 Serine/threonine-protein kinase DCLK1 9201 reviewed Kinase
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 4864 reviewed Transporter
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O43603 BXGT004604 Galanin receptor type 2 8811 reviewed G-protein coupled receptor
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
P00325 BXGT005498 Alcohol dehydrogenase 1B 125 reviewed Enzyme
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00966 BXGT005707 Argininosuccinate synthase 445 reviewed Enzyme
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02741 BXGT005936 C-reactive protein 1401 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11766 BXGT007745 Alcohol dehydrogenase class-3 128 reviewed Enzyme
P15924 BXGT008171 Desmoplakin 1832 reviewed Cellular structure
P16070 BXGT008186 CD44 antigen 960 reviewed
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P21266 BXGT008632 Glutathione S-transferase Mu 3 2947 reviewed
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31941 BXGT009585 DNA dC->dU-editing enzyme APOBEC-3A 200315 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P60568 BXGT011315 Interleukin-2 3558 reviewed
P78527 BXGT011846 DNA-dependent protein kinase catalytic subunit 5591 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q13126 BXGT013313 S-methyl-5'-thioadenosine phosphorylase 4507 reviewed Enzyme
Q13509 BXGT013366 Tubulin beta-3 chain 10381 reviewed Cellular structure
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q5T6L4 BXGT015848 Argininosuccinate synthase 1 isoform 1 445 unreviewed
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q8IUQ4 BXGT018336 E3 ubiquitin-protein ligase SIAH1 6477 reviewed
Q969S2 BXGT019612 Endonuclease 8-like 2 252969 reviewed
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
Q16254 BXGT023368 Transcription factor E2F4 1874 reviewed Nucleic acid binding
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease