Showing entry for Borderline Personality Disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000360
Disease NameBorderline Personality Disorder
Disease CUI IdC0006012
MeSH Codes F03  
Disease Class NameMental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id DOID:150  
Disease Ontology Class Namedisease of mental health
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14732 BXGT004086 Inositol monophosphatase 2 3613 reviewed Enzyme
O43708 BXGT004617 Maleylacetoacetate isomerase 2954 reviewed
O60427 BXGT004875 Acyl-CoA (8-3)-desaturase 3992 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
O95696 BXGT005390 Bromodomain-containing protein 1 23774 reviewed
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P19174 BXGT008467 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5335 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20472 BXGT008578 Parvalbumin alpha 5816 reviewed Calcium-binding protein
P20711 BXGT008594 Aromatic-L-amino-acid decarboxylase 1644 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P25325 BXGT009038 3-mercaptopyruvate sulfurtransferase 4357 reviewed Enzyme
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27338 BXGT009172 Amine oxidase [flavin-containing] B 4129 reviewed
P28221 BXGT009237 5-hydroxytryptamine receptor 1D 3352 reviewed G-protein coupled receptor
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30559 BXGT009442 Oxytocin receptor 5021 reviewed G-protein coupled receptor
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35052 BXGT009788 Glypican-1 2817 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P46098 BXGT010507 5-hydroxytryptamine receptor 3A 3359 reviewed Ion channel
P47870 BXGT010591 Gamma-aminobutyric acid receptor subunit beta-2 2561 reviewed Ion channel
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51575 BXGT010861 P2X purinoceptor 1 5023 reviewed Ion channel
P53985 BXGT011022 Monocarboxylate transporter 1 6566 reviewed Transporter
P54219 BXGT011037 Chromaffin granule amine transporter 6570 reviewed Transporter
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q02363 BXGT012650 DNA-binding protein inhibitor ID-2 3398 reviewed Transcription factor
Q02779 BXGT012670 Mitogen-activated protein kinase kinase kinase 10 4294 reviewed Kinase
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13324 BXGT013340 Corticotropin-releasing factor receptor 2 1395 reviewed G-protein coupled receptor
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 1135 reviewed Ion channel
Q15858 BXGT013610 Sodium channel protein type 9 subunit alpha 6335 reviewed Ion channel
Q16555 BXGT013638 Dihydropyrimidinase-related protein 2 1808 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q6W5P4 BXGT016588 Neuropeptide S receptor 387129 reviewed
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8IVS2 BXGT018349 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial 27349 reviewed
Q8IWT1 BXGT018357 Sodium channel subunit beta-4 6330 reviewed Ion channel
Q8NEM0 BXGT018555 Microcephalin 79648 reviewed Nucleic acid binding
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96HC4 BXGT019671 PDZ and LIM domain protein 5 10611 reviewed Cellular structure
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99705 BXGT019951 Melanin-concentrating hormone receptor 1 2847 reviewed G-protein coupled receptor
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9UBL9 BXGT021656 P2X purinoceptor 2 22953 reviewed Ion channel
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha 815 reviewed Kinase
Q9Y233 BXGT022210 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 10846 reviewed
Q9Y698 BXGT022323 Voltage-dependent calcium channel gamma-2 subunit 10369 reviewed Ion channel
Q7Z3S7 BXGT022658 Voltage-dependent calcium channel subunit alpha-2/delta-4 93589 reviewed Ion channel
Q15878 BXGT022659 Voltage-dependent R-type calcium channel subunit alpha-1E 777 reviewed Ion channel
Q86XP1 BXGT022668 Diacylglycerol kinase eta 160851 reviewed Kinase
P17752 BXGT023118 Tryptophan 5-hydroxylase 1 7166 reviewed
Q9UKP6 BXGT024239 Urotensin-2 receptor 2837 reviewed G-protein coupled receptor
Q8TBG4 BXGT025667 Ethanolamine-phosphate phospho-lyase 64850 reviewed
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease