Showing entry for Bronchopulmonary Dysplasia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000390
Disease NameBronchopulmonary Dysplasia
Disease CUI IdC0006287
MeSH Codes C16   C08  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00469 BXGT003926 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 5352 reviewed Enzyme
O14732 BXGT004086 Inositol monophosphatase 2 3613 reviewed Enzyme
O15496 BXGT004175 Group 10 secretory phospholipase A2 8399 reviewed Enzyme
O43708 BXGT004617 Maleylacetoacetate isomerase 2954 reviewed
O60427 BXGT004875 Acyl-CoA (8-3)-desaturase 3992 reviewed
O60568 BXGT004885 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 8985 reviewed Enzyme
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O94760 BXGT005328 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 23576 reviewed Enzyme
O95696 BXGT005390 Bromodomain-containing protein 1 23774 reviewed
O95865 BXGT005404 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 23564 reviewed Enzyme
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07478 BXGT006630 Trypsin-2 5645 reviewed Enzyme
P07737 BXGT006663 Profilin-1 5216 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08311 BXGT006762 Cathepsin G 1511 reviewed Enzyme
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P09848 BXGT006929 Lactase-phlorizin hydrolase 3938 reviewed Enzyme
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10909 BXGT007630 Clusterin 1191 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14151 BXGT007990 L-selectin 6402 reviewed
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16109 BXGT008194 P-selectin 6403 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P18075 BXGT008375 Bone morphogenetic protein 7 655 reviewed Signaling
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P19174 BXGT008467 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5335 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20472 BXGT008578 Parvalbumin alpha 5816 reviewed Calcium-binding protein
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21709 BXGT008685 Ephrin type-A receptor 1 2041 reviewed Kinase
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P23528 BXGT008879 Cofilin-1 1072 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P24158 BXGT008951 Myeloblastin 5657 reviewed Enzyme
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30046 BXGT009396 D-dopachrome decarboxylase 1652 reviewed Enzyme
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35052 BXGT009788 Glypican-1 2817 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P47870 BXGT010591 Gamma-aminobutyric acid receptor subunit beta-2 2561 reviewed Ion channel
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P51512 BXGT010850 Matrix metalloproteinase-16 4325 reviewed Enzyme
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51575 BXGT010861 P2X purinoceptor 1 5023 reviewed Ion channel
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 3654 reviewed Kinase
P54219 BXGT011037 Chromaffin granule amine transporter 6570 reviewed Transporter
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55774 BXGT011124 C-C motif chemokine 18 6362 reviewed Signaling
P55957 BXGT011137 BH3-interacting domain death agonist 637 reviewed
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P58753 BXGT011247 Toll/interleukin-1 receptor domain-containing adapter protein 114609 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P63165 BXGT011506 Small ubiquitin-related modifier 1 7341 reviewed
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P98066 BXGT012225 Tumor necrosis factor-inducible gene 6 protein 7130 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q02363 BXGT012650 DNA-binding protein inhibitor ID-2 3398 reviewed Transcription factor
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q08257 BXGT012975 Quinone oxidoreductase 1429 reviewed
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 659 reviewed Kinase
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 1135 reviewed Ion channel
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16555 BXGT013638 Dihydropyrimidinase-related protein 2 1808 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q6W5P4 BXGT016588 Neuropeptide S receptor 387129 reviewed
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8IWT1 BXGT018357 Sodium channel subunit beta-4 6330 reviewed Ion channel
Q8NEM0 BXGT018555 Microcephalin 79648 reviewed Nucleic acid binding
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96HC4 BXGT019671 PDZ and LIM domain protein 5 10611 reviewed Cellular structure
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96PD4 BXGT019705 Interleukin-17F 112744 reviewed
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99705 BXGT019951 Melanin-concentrating hormone receptor 1 2847 reviewed G-protein coupled receptor
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NP99 BXGT021148 Triggering receptor expressed on myeloid cells 1 54210 reviewed
Q9NZN1 BXGT021279 Interleukin-1 receptor accessory protein-like 1 11141 reviewed Receptor
Q9UBL9 BXGT021656 P2X purinoceptor 2 22953 reviewed Ion channel
Q9UJU2 BXGT021730 Lymphoid enhancer-binding factor 1 51176 reviewed
Q9UKA9 BXGT021740 Polypyrimidine tract-binding protein 2 58155 reviewed
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha 815 reviewed Kinase
Q9Y233 BXGT022210 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 10846 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y3B4 BXGT022255 Splicing factor 3B subunit 6 51639 reviewed
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y698 BXGT022323 Voltage-dependent calcium channel gamma-2 subunit 10369 reviewed Ion channel
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q7Z3S7 BXGT022658 Voltage-dependent calcium channel subunit alpha-2/delta-4 93589 reviewed Ion channel
Q15878 BXGT022659 Voltage-dependent R-type calcium channel subunit alpha-1E 777 reviewed Ion channel
Q86XP1 BXGT022668 Diacylglycerol kinase eta 160851 reviewed Kinase
P41271 BXGT022908 Neuroblastoma suppressor of tumorigenicity 1 4681 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q9UK05 BXGT023094 Growth/differentiation factor 2 2658 reviewed Signaling
P17752 BXGT023118 Tryptophan 5-hydroxylase 1 7166 reviewed
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9UKP6 BXGT024239 Urotensin-2 receptor 2837 reviewed G-protein coupled receptor
Q96A54 BXGT024681 Adiponectin receptor protein 1 51094 reviewed Receptor
Q8TBG4 BXGT025667 Ethanolamine-phosphate phospho-lyase 64850 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease