Showing entry for Cytochrome b5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005473
Protein NameCytochrome b5
Uniport IdP00167
GeneCYB5A
Gene Id1528
DomainCyt-b5
Pfam PF00173  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019852 L-ascorbic acid metabolic process
Biological Process GO:0046686 response to cadmium ion
molecular function GO:0004129 cytochrome-c oxidase activity
molecular function GO:0009055 electron transfer activity
molecular function GO:0019899 enzyme binding
molecular function GO:0020037 heme binding
molecular function GO:0046872 metal ion binding
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0005741 mitochondrial outer membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-196836 Vitamin C (ascorbate) metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004158 BXGD000261 Athetosis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009777 BXGD000630 Conn Adenoma Neoplasms; Endocrine System Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0010520 BXGD000675 Cyanosis Pathological Conditions, Signs and Symptoms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013390 BXGD000828 Dysmenorrhea Pathological Conditions, Signs and Symptoms
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014877 BXGD000967 Esotropia Eye Diseases; Nervous System Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0018418 BXGD001192 Gynecomastia Skin and Connective Tissue Diseases
C0020758 BXGD001467 Congenital ichthyosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0025322 BXGD001863 Premature Menopause Female Urogenital Diseases and Pregnancy Complications
C0025637 BXGD001879 Methemoglobinemia Hemic and Lymphatic Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0034012 BXGD002449 Delayed Puberty Endocrine System Diseases
C0034186 BXGD002469 Pyelonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0079154 BXGD003065 Congenital Nonbullous Ichthyosiform Erythroderma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0079583 BXGD003082 Ichthyosiform Erythroderma, Congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151639 BXGD003452 Decreased fertility in females Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151640 BXGD003453 Decreased fertility in males Male Urogenital Diseases
C0206667 BXGD004228 Adrenal Cortical Adenoma Neoplasms; Endocrine System Diseases
C0220724 BXGD004332 CONSTRICTING BANDS, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0231807 BXGD004524 Dyspnea on exertion Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0232939 BXGD004568 Primary physiologic amenorrhea Pathological Conditions, Signs and Symptoms
C0235991 BXGD004802 Small for gestational age (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0238395 BXGD004922 Male Pseudohermaphroditism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0241011 BXGD005073 Low serum estradiol levels
C0241355 BXGD005092 Small testicle
C0241816 BXGD005115 Global brain atrophy
C0266362 BXGD005657 Ambiguous Genitalia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0266399 BXGD005663 Infantile uterus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0268285 BXGD005883 Adrenal hyperplasia, congenital, type 5 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0272087 BXGD006303 Congenital Methemoglobinemia Hemic and Lymphatic Diseases
C0302511 BXGD006849 Small for gestational age fetus Pathological Conditions, Signs and Symptoms
C0341787 BXGD007422 Bifid scrotum
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0345309 BXGD007725 Hypoplasia of vagina Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0349588 BXGD007933 Short stature
C0426970 BXGD008598 Spastic Quadriplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0541764 BXGD009259 Delayed bone age
C0542514 BXGD009277 Blue sclera Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0740279 BXGD009973 Cerebellar atrophy
C0751093 BXGD010317 Dystonia, Limb Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0853087 BXGD010964 Nail abnormality Pathological Conditions, Signs and Symptoms
C0854373 BXGD011017 Lip discoloration
C0948896 BXGD011563 Primary hypogonadism Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1277241 BXGD012110 Delayed myelination Mental Disorders
C1291557 BXGD012217 Deficiency of lyase
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1611743 BXGD013456 Familial (FPAH)
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1837397 BXGD014227 Severe global developmental delay
C1848178 BXGD014909 Female external genitalia in individual with 46,XY karyotype
C1858573 BXGD015809 Sparse pubic hair
C1858574 BXGD015810 Sparse axillary hair
C1859014 BXGD015843 Primary gonadal insufficiency
C1862863 BXGD016138 Sparse body hair
C2673427 BXGD017201 METHEMOGLOBINEMIA TYPE IV Hemic and Lymphatic Diseases
C2677328 BXGD017371 Cerebral hypomyelination
C2749559 BXGD017623 Methemoglobinemia, Type I Hemic and Lymphatic Diseases
C2749560 BXGD017624 Methemoglobinemia, Type Ii Hemic and Lymphatic Diseases
C2751824 BXGD017742 46, XY Disorders of Sex Development Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C3665425 BXGD019286 Hemoglobin M Disease Hemic and Lymphatic Diseases
C4021550 BXGD020666 Elevated circulating follicle stimulating hormone level
C4021551 BXGD020667 Absence of secondary sex characteristics
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4021823 BXGD020808 Ambiguous genitalia, male Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C4022769 BXGD020994 Small basal ganglia
C4022996 BXGD021057 Abnormal sex determination
C4023101 BXGD021106 Elevated circulating luteinizing hormone level
C4024641 BXGD021355 Enlarged polycystic ovaries Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4024936 BXGD021486 Temporal cortical atrophy
C4024965 BXGD021506 Frontal cortical atrophy
C4073137 BXGD022045 Decreased serum testosterone level
C4285231 BXGD022444 METHEMOGLOBINEMIA AND AMBIGUOUS GENITALIA
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002587 Chromium 52
BXGC0008676 Haem 616.49
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein