Showing entry for Abnormality of metabolism/homeostasis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD020766
Disease NameAbnormality of metabolism/homeostasis
Disease CUI IdC4021768
MeSH Codes   
Disease Class Name
Semantic TypeFinding
Human Phenotype Ontology Id HP:0001939  
Human Phenotype Ontology TermAbnormality of metabolism/homeostasis
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00462 BXGT003925 Beta-mannosidase 4126 reviewed Enzyme
O14832 BXGT004104 Phytanoyl-CoA dioxygenase, peroxisomal 5264 reviewed
O43272 BXGT004580 Proline dehydrogenase 1, mitochondrial 5625 reviewed Enzyme
O43570 BXGT004601 Carbonic anhydrase 12 771 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60840 BXGT004901 Voltage-dependent L-type calcium channel subunit alpha-1F 778 reviewed Ion channel
O94903 BXGT005339 Pyridoxal phosphate homeostasis protein 11212 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00167 BXGT005473 Cytochrome b5 1528 reviewed Enzyme
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P02730 BXGT005935 Band 3 anion transport protein 6521 reviewed Transporter
P02792 BXGT005966 Ferritin light chain 2512 reviewed Storage
P04181 BXGT006165 Ornithine aminotransferase, mitochondrial 4942 reviewed Enzyme
P04264 BXGT006176 Keratin, type II cytoskeletal 1 3848 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04899 BXGT006281 Guanine nucleotide-binding protein G(i) subunit alpha-2 2771 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07602 BXGT006646 Prosaposin 5660 reviewed
P08185 BXGT006742 Corticosteroid-binding globulin 866 reviewed Enzyme modulator
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P09884 BXGT006937 DNA polymerase alpha catalytic subunit 5422 reviewed
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11509 BXGT007716 Cytochrome P450 2A6 1548 reviewed
P11586 BXGT007723 C-1-tetrahydrofolate synthase, cytoplasmic 4522 reviewed Enzyme
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P12830 BXGT007852 Cadherin-1 999 reviewed
P12955 BXGT007865 Xaa-Pro dipeptidase 5184 reviewed Enzyme
P14410 BXGT008009 Sucrase-isomaltase, intestinal 6476 reviewed Enzyme
P14679 BXGT008039 Tyrosinase 7299 reviewed Enzyme
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P19367 BXGT008476 Hexokinase-1 3098 reviewed Kinase
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P20933 BXGT008618 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase 175 reviewed Enzyme
P21333 BXGT008638 Filamin-A 2316 reviewed
P22314 BXGT008755 Ubiquitin-like modifier-activating enzyme 1 7317 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P23945 BXGT008931 Follicle-stimulating hormone receptor 2492 reviewed G-protein coupled receptor
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31939 BXGT009584 Bifunctional purine biosynthesis protein PURH 471 reviewed Enzyme
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P37058 BXGT009956 Testosterone 17-beta-dehydrogenase 3 3293 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P49281 BXGT010689 Natural resistance-associated macrophage protein 2 4891 reviewed Transporter
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase 501 reviewed Enzyme
P50542 BXGT010808 Peroxisomal targeting signal 1 receptor 5830 reviewed Transporter
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P51580 BXGT010864 Thiopurine S-methyltransferase 7172 reviewed
P51649 BXGT010872 Succinate-semialdehyde dehydrogenase, mitochondrial 7915 reviewed Enzyme
P52952 BXGT010966 Homeobox protein Nkx-2.5 1482 reviewed Transcription factor
P54802 BXGT011081 Alpha-N-acetylglucosaminidase 4669 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P68871 BXGT011615 Hemoglobin subunit beta 3043 reviewed
P69905 BXGT011649 Hemoglobin subunit alpha 3040 reviewed
P78508 BXGT011845 ATP-sensitive inward rectifier potassium channel 10 3766 reviewed Ion channel
P98155 BXGT012226 Very low-density lipoprotein receptor 7436 reviewed
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q04446 BXGT012764 1,4-alpha-glucan-branching enzyme 2632 reviewed Enzyme
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q14203 BXGT013455 Dynactin subunit 1 1639 reviewed Chaperone
Q14982 BXGT013518 Opioid-binding protein/cell adhesion molecule 4978 reviewed
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 51 reviewed Enzyme
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15858 BXGT013610 Sodium channel protein type 9 subunit alpha 6335 reviewed Ion channel
Q92834 BXGT019381 X-linked retinitis pigmentosa GTPase regulator 6103 reviewed
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q9BQB6 BXGT020108 Vitamin K epoxide reductase complex subunit 1 79001 reviewed Enzyme
Q9H1R3 BXGT020446 Myosin light chain kinase 2, skeletal/cardiac muscle 85366 reviewed Kinase
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H6X2 BXGT020486 Anthrax toxin receptor 1 84168 reviewed Receptor
Q9NX14 BXGT021242 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 54539 reviewed Enzyme
Q9UBK8 BXGT021655 Methionine synthase reductase 4552 reviewed
Q9Y223 BXGT022207 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase 10020 reviewed Enzyme
Q9Y289 BXGT022226 Sodium-dependent multivitamin transporter 8884 reviewed Transporter
Q9Y5L0 BXGT022296 Transportin-3 23534 reviewed Transporter
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P27918 BXGT025485 Properdin 5199 reviewed
Q14566 BXGT025969 DNA replication licensing factor MCM6 4175 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease