adisease

Showing entry for alpha-Thalassemia

General Disease Information
BXGD Id	BXGD000107
Disease Name	alpha-Thalassemia
Disease CUI Id	C0002312
MeSH Codes	C16 C15
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630
Disease Ontology Class Name	genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
P02008	BXGT005832	Hemoglobin subunit zeta	3050	reviewed
P02042	BXGT005834	Hemoglobin subunit delta	3045	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P19224	BXGT008468	UDP-glucuronosyltransferase 1-6	54578	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	54658	reviewed
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	54657	reviewed
P28066	BXGT009227	Proteasome subunit alpha type-5	5686	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P52209	BXGT010923	6-phosphogluconate dehydrogenase, decarboxylating	5226	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P69891	BXGT011646	Hemoglobin subunit gamma-1	3047	reviewed
P69892	BXGT011647	Hemoglobin subunit gamma-2	3048	reviewed
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P81172	BXGT011935	Hepcidin	57817	reviewed
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q8N4E7	BXGT018511	Ferritin, mitochondrial	94033	reviewed	Storage
Q9HAW7	BXGT020508	UDP-glucuronosyltransferase 1-7	54577	reviewed
Q9HAW8	BXGT020509	UDP-glucuronosyltransferase 1-10	54575	reviewed
Q9HAW9	BXGT020510	UDP-glucuronosyltransferase 1-8	54576	reviewed
Q9NZD4	BXGT021271	Alpha-hemoglobin-stabilizing protein	51327	reviewed	Chaperone
Q9UER7	BXGT021672	Death domain-associated protein 6	1616	reviewed
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	10599	reviewed	Transporter
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q9BYE2	BXGT024631	Transmembrane protease serine 13	84000	reviewed	Enzyme
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}