Showing entry for ADP/ATP translocase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006325
Protein NameADP/ATP translocase 2
Uniport IdP05141
GeneSLC25A5
Gene Id292
DomainMito_carr
Pfam PF00153  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04022 cGMP-PKG signaling pathway
4. Cellular Processes 4.2 Cell growth and death hsa04217 Necroptosis
4. Cellular Processes 4.2 Cell growth and death hsa04218 Cellular senescence
6. Human Diseases 6.4 Neurodegenerative diseases hsa05012 Parkinson disease
6. Human Diseases 6.4 Neurodegenerative diseases hsa05016 Huntington disease
6. Human Diseases 6.9 Infectious diseases: Viral hsa05164 Influenza A
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051503 adenine nucleotide transport
Biological Process GO:1990830 cellular response to leukemia inhibitory factor
Biological Process GO:0007059 chromosome segregation
Biological Process GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0050796 regulation of insulin secretion
Biological Process GO:0016032 viral process
molecular function GO:0000295 adenine nucleotide transmembrane transporter activity
molecular function GO:0015207 adenine transmembrane transporter activity
molecular function GO:0005347 ATP transmembrane transporter activity
molecular function GO:0003723 RNA binding
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0042645 mitochondrial nucleoid
cellular component GO:0005739 mitochondrion
cellular component GO:0071817 MMXD complex
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-162906 HIV Infection
R-HSA-162909 Host Interactions of HIV factors
R-HSA-1643685 Disease
R-HSA-176033 Interactions of Vpr with host cellular proteins
R-HSA-180897 Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization
R-HSA-382551 Transport of small molecules
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-5663205 Infectious disease
R-HSA-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0018818 BXGD001236 Ventricular Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0162670 BXGD003970 Mitochondrial Myopathies Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677936 BXGD009737 Refractory cancer Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0949541 BXGD011578 Hurthle Cell Tumor Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1378050 BXGD012931 Oncocytic Neoplasm
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510502 BXGD013175 Oxyphilic Adenoma Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein