Showing entry for Neuronal acetylcholine receptor subunit alpha-4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006896
Protein NameNeuronal acetylcholine receptor subunit alpha-4
Uniport IdP09483
GeneChrna4
Gene Id25590
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0095500 acetylcholine receptor signaling pathway
Biological Process GO:0001508 action potential
Biological Process GO:0042113 B cell activation
Biological Process GO:0035095 behavioral response to nicotine
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0050890 cognition
Biological Process GO:0006281 DNA repair
Biological Process GO:0035640 exploration behavior
Biological Process GO:0060080 inhibitory postsynaptic potential
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0051899 membrane depolarization
Biological Process GO:0050877 nervous system process
Biological Process GO:0033603 positive regulation of dopamine secretion
Biological Process GO:1903048 regulation of acetylcholine-gated cation channel activity
Biological Process GO:0014059 regulation of dopamine secretion
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0007585 respiratory gaseous exchange by respiratory system
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0035094 response to nicotine
Biological Process GO:0006979 response to oxidative stress
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0007165 signal transduction
Biological Process GO:0007271 synaptic transmission, cholinergic
molecular function GO:0042166 acetylcholine binding
molecular function GO:0022848 acetylcholine-gated cation-selective channel activity
molecular function GO:0015464 acetylcholine receptor activity
molecular function GO:0008144 drug binding
molecular function GO:0005216 ion channel activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0044877 protein-containing complex binding
cellular component GO:0005892 acetylcholine-gated channel complex
cellular component GO:0098981 cholinergic synapse
cellular component GO:0030425 dendrite
cellular component GO:0098691 dopaminergic synapse
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099060 integral component of postsynaptic specialization membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000195 O-Methylcorypalline 207.27
BXGC0000409 Choline 104.17
BXGC0000555 3-Ethylpyridine 107.15
BXGC0000982 L-Homocysteine 135.19
BXGC0001451 (S)-Laudanosine 357.44
BXGC0001488 Erysodine 299.36
BXGC0001518 (S)-2-Propylpiperidine 127.23
BXGC0001589 Arecoline 155.19
BXGC0001614 Myosmine 146.19
BXGC0002796 Nicotine 162.23
BXGC0002987 2,6-Diemthyl-pyridine 107.15
BXGC0002989 2-Ethylpyridine 107.15
BXGC0002992 2-Methylpyridine 93.13
BXGC0003004 3-Methylpyridine 93.13
BXGC0003010 4-Methylpyridine 93.13
BXGC0003102 Acetylcholine 146.21
BXGC0003128 Cotinine 176.22
BXGC0003965 Prolamine 71.12
BXGC0005874 Racemethionine 149.21
BXGC0006183 L-Cystine 240.3
BXGC0006243 Piperidine 85.15
BXGC0007675 Pyridine 79.1
BXGC0016637 6-Methoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-7-Ol 193.11
BXGC0019419 2-hydroxypyridine 95.04
BXGC0021495 Dl-Anabasine 162.12
BXGC0021636 2-[(2R,6S)-1-Methyl-6-Phenacylpiperidin-2-Yl]-1-Phenylethanone 335.19
BXGC0026677 4-methylpiperidine 99.1
BXGC0028249 N-methylcytisine 204.13
BXGC0030901 Morphine 285.14
BXGC0033981 Cyfusine 176.09
BXGC0035349 (+)-Crispine A 233.14
BXGC0035415 R-Nicotine 162.12
BXGC0035631 cytisine 190.11
BXGC0038169 (-)-Lobeline 337.2
BXGC0040367 7-Methoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-6-Ol 193.11
BXGC0042179 Atropine 289.17
BXGC0042293 N-methylcytisine 204.13
BXGC0042462 Cysteine 121.02
BXGC0046653 (+/-)Nicotine 162.12
BXGC0049005 (1R)-2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-Phenylethyl]-1-Methylpiperidin-2-Yl]-1-Phenylethanol 339.22
BXGC0049630 6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinoline 191.09
BXGC0050754 Cytisine 190.11
BXGC0052646 Tubocurarine 609.3
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein