Showing entry for Fluoxetine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0042510
Compound NameFluoxetine
Structure
FormulaC17H18F3NO
InchiKeyRTHCYVBBDHJXIQ-UHFFFAOYSA-N
SMILESCNCCC(c1ccccc1)Oc1ccc(cc1)C(F)(F)F
InchiInChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
IUPACN-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Molecular Weight309.13
Pubchem Id3386
Chembl IdCHEMBL41
Targets of Information Source
DrugBank DB00472
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 approved; vet_approved inhibitor
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C approved; vet_approved antagonist
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 approved; vet_approved antagonist
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 approved; vet_approved antagonist
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 approved; vet_approved antagonist
P61024 BXGT011350 Cyclin-dependent kinases regulatory subunit 1 reviewed Enzyme modulator CKS1B approved; vet_approved -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 approved; vet_approved inhibitor
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 30130
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 6670 - - 19500
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 1.1 - - 7.3
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 1560 - - 1020
reviewed BXGT011358 Ubiquitin-conjugating enzyme E2 N reviewed UBE2N - >20000 - -
reviewed BXGT008472 5-hydroxytryptamine receptor 1A reviewed Htr1a >10000 - - -
reviewed BXGT009272 5-hydroxytryptamine receptor 1B reviewed Htr1b 6165.95 - - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a 1819.7 - - -
reviewed BXGT009849 5-hydroxytryptamine receptor 3A reviewed Htr3a >10000 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 10.8 - - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a 1000 - - -
reviewed BXGT010360 Alpha-1A adrenergic receptor reviewed Adra1a 1000 - - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 3160 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 1 - - -
reviewed BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 1100 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 270 - - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 >10000 - - -
reviewed BXGT009532 5-hydroxytryptamine receptor 6 reviewed Htr6 1770 - - -
reviewed BXGT006837 5-hydroxytryptamine receptor 1A reviewed G-protein coupled receptor HTR1A >10000 - - -
reviewed BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C 280 - - -
reviewed BXGT009814 Alpha-1A adrenergic receptor reviewed G-protein coupled receptor ADRA1A 3800 - - -
reviewed BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A >10000 - - -
reviewed BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 590 - - -
reviewed BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 >10000 - - -
reviewed BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 5400 - - -
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 1030 - - -
reviewed BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 2700 - - -
reviewed BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 1000 - - -
reviewed BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 2900 - - -
reviewed BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 2700 - - -
reviewed BXGT009621 5-hydroxytryptamine receptor 7 reviewed Htr7 1000 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 10.9 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 1.96 - - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a 708 - - -
reviewed BXGT006838 5-hydroxytryptamine receptor 2C reviewed Htr2c 42.6 - - -
reviewed BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A 147.91 - - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a 147.91 - - -
reviewed BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B >10000 - - -
reviewed BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C 112.2 - - -
reviewed BXGT006838 5-hydroxytryptamine receptor 2C reviewed Htr2c 23.98 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 20 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 0.9 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 2 - - -
reviewed BXGT008472 5-hydroxytryptamine receptor 1A reviewed Htr1a 8313 - - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a 141 - - -
reviewed BXGT009814 Alpha-1A adrenergic receptor reviewed G-protein coupled receptor ADRA1A 1353 - - -
reviewed BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A 3090 - - -
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 512 - - -
reviewed BXGT009533 Histamine H1 receptor reviewed HRH1 933 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 777 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 2186 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 0.81 - - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 3600 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 240 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 6.8 - - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a 710 - - -
reviewed BXGT006838 5-hydroxytryptamine receptor 2C reviewed Htr2c 160 - - -
reviewed BXGT010360 Alpha-1A adrenergic receptor reviewed Adra1a >10000 - - -
reviewed BXGT008728 Alpha-2C adrenergic receptor reviewed Adra2c 2800 - - -
reviewed BXGT007586 Beta-2 adrenergic receptor reviewed Adrb2 >10000 - - -
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 3100 - - -
reviewed BXGT008440 D(1A) dopamine receptor reviewed Drd1 >10000 - - -
reviewed BXGT011367 D(2) dopamine receptor reviewed Drd2 >10000 - - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 5000 - - -
reviewed BXGT009534 Histamine H1 receptor reviewed Hrh1 3200 - - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 784 - - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 2080 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 9.58 - - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a 299 - - -
reviewed BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B 5030 - - -
reviewed BXGT006838 5-hydroxytryptamine receptor 2C reviewed Htr2c 50 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 5.7 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 1.1 - - -
reviewed BXGT009814 Alpha-1A adrenergic receptor reviewed G-protein coupled receptor ADRA1A 3171 - - -
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 702 - - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 3764 - - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 5960 - - -
reviewed BXGT009533 Histamine H1 receptor reviewed HRH1 1548 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 599 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 574 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 7 - - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 4752 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 1022 - - -
reviewed BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A 245.47 - - -
reviewed BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C 398.11 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 10.3 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 3.58 - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 - 2535 - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 - >10000 - -
reviewed BXGT016017 Sodium-dependent dopamine transporter reviewed Slc6a3 11 - - -
reviewed BXGT004748 Sodium-dependent noradrenaline transporter reviewed Slc6a2 85 - - -
reviewed BXGT016017 Sodium-dependent dopamine transporter reviewed Slc6a3 >2000 - - -
reviewed BXGT011367 D(2) dopamine receptor reviewed Drd2 - >100 - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 - 15 - -
reviewed BXGT006838 5-hydroxytryptamine receptor 2C reviewed Htr2c 109 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 5.6 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 - 130 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 3.5 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 7.3 - - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 >2500 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 150 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 4410 - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 - 18400 - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 - 4410 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 32.4 - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 2.72 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 2 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 2.8 - - -
reviewed BXGT022297 Histamine H3 receptor reviewed G-protein coupled receptor HRH3 7300 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 2.2 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 2.9 - - -
reviewed BXGT008717 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Cacna1c - 2820 - -
reviewed BXGT010867 Cytochrome P450 2J2 reviewed CYP2J2 - >50000 - -
reviewed BXGT005957 Serum albumin reviewed Alb - - 3.6 -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 8.7 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 9.4 - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 2.7 - - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 - 6000 - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 - 2000 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 47 - -
reviewed BXGT009707 Cytochrome P450 2C19 reviewed CYP2C19 - 40 - -
reviewed BXGT005348 Potassium channel subfamily K member 2 reviewed Ion channel KCNK2 - 19000 - -
reviewed BXGT005348 Potassium channel subfamily K member 2 reviewed Ion channel KCNK2 - 14000 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 2.5 - -
reviewed BXGT008472 5-hydroxytryptamine receptor 1A reviewed Htr1a - 15 - -
reviewed BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE - 130 - -
reviewed BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 - 3100 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 5.2 - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a >1000 - - -
reviewed BXGT008160 Alpha-1B adrenergic receptor reviewed Adra1b 5260 - - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 1092 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 12.2 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 - 8300 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 3.17 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - - 0.81 -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 - - 3600 -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 - - 240 -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 3050 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 14 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 22 - - -
reviewed BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 - 1514 - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 4580 - - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 1900 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 440 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 0.72 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 2000 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 48 - - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 6000 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 39.4 - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 3.9 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 - 5200 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 16 - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 - 4400 - -
reviewed BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE - >10000 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 180 - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 - 563 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 10 - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 - 1020 - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 6670 - - -
reviewed BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 1560 - - -
reviewed BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 - 19500 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 7 - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 48 - - -
reviewed BXGT008936 Sodium-dependent dopamine transporter reviewed Slc6a3 - 6000 - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 41 - - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - 3.1 - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 - 12.6 - -
reviewed BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 - - - 2.7
reviewed BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C 72 - - -
reviewed BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 - 1513.56 - -
reviewed BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 - 457.09 - -
reviewed BXGT007592 Cytochrome P450 2C8 reviewed CYP2C8 294000 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 - 6.3 - -
reviewed BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed SIGMAR1 - 851 - -
reviewed BXGT009026 Potassium voltage-gated channel subfamily C member 1 reviewed Kcnc1 - 13100 - -
CHEMBL CHEMBL41
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A pKB '=' 7 -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 10 nM
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 '=' 194 nM
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki '=' 698 nM
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki '=' 605 nM
P23944 BXGT008930 Alpha-1D adrenergic receptor reviewed - Adra1d Ki '=' 605 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki '=' 605 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 3 nM
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 '=' 3203 nM
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki '=' 976 nM
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki '=' 771 nM
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Activity - - -
O95069 BXGT005348 Potassium channel subfamily K member 2 reviewed Ion channel KCNK2 Inhibition '=' 84 %
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Log IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 2535 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a IC50 - - -
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b IC50 - - -
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d IC50 - - -
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c IC50 - - -
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b IC50 - - -
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a IC50 - - -
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 IC50 - - -
P28565 BXGT009273 5-hydroxytryptamine receptor 1D reviewed - Htr1d IC50 '=' 15 nM
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 '=' 15 nM
P30940 BXGT009484 5-hydroxytryptamine receptor 1F reviewed - Htr1f IC50 '=' 15 nM
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 '=' 15 nM
Q16678 BXGT013656 Cytochrome P450 1B1 reviewed Enzyme CYP1B1 IC50 '=' 475000 nM
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 18492 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 5 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 RFU '=' 0 -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ratio IC50 '=' 2 -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 '=' 1528 nM
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Activity - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 11885 nM
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 1303 nM
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki '=' 771 nM
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki '=' 10066 nM
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 '=' 119 nM
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki '=' 62 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Inhibition - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki '=' 1394 nM
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Potency - 11220 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 '>' 10000 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 1020 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 23280 nM
P10632 BXGT007592 Cytochrome P450 2C8 reviewed - CYP2C8 Inhibition '<' 10 %
P10632 BXGT007592 Cytochrome P450 2C8 reviewed - CYP2C8 Kinact '=' 0 min-1
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 9 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 457 nM
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 58047 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 4410 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Inhibition '=' 56 %
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Kd '=' 0 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki '=' 1900 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Inhibition '=' 6 %
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 2 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 39 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 8 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Efficacy '=' 81 %
P10632 BXGT007592 Cytochrome P450 2C8 reviewed - CYP2C8 Ki '=' 294000 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 2000 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 IC50 '=' 12 nM
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki '=' 1560 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 707 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 47 nM
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Inhibition '>' 50 %
O15296 BXGT004148 Arachidonate 15-lipoxygenase B reviewed Enzyme ALOX15B Potency - 15848 nM
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Potency - 14125 nM
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
O55192 BXGT004748 Sodium-dependent noradrenaline transporter reviewed - Slc6a2 Ki '=' 85 nM
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 2 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Inhibition '=' 26 %
Q9WTR4 BXGT021930 Transporter unreviewed - Slc6a2 Ki '=' 176 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 7 nM
P23977 BXGT008936 Sodium-dependent dopamine transporter reviewed - Slc6a3 Ratio '=' 624 -
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ratio '=' 624 -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki '=' 1292 nM
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki '=' 6 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 0 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 '=' 499 nM
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
P08908 BXGT006837 5-hydroxytryptamine receptor 1A reviewed G-protein coupled receptor HTR1A EC50 - - -
P28565 BXGT009273 5-hydroxytryptamine receptor 1D reviewed - Htr1d Inhibition '=' 13 %
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Inhibition '=' 13 %
P30940 BXGT009484 5-hydroxytryptamine receptor 1F reviewed - Htr1f Inhibition '=' 13 %
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Inhibition '=' 13 %
Q9Y5N1 BXGT022297 Histamine H3 receptor reviewed G-protein coupled receptor HRH3 Ki '=' 7300 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki '=' 6000 nM
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 '=' 130 nM
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki '=' 210 nM
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Activity - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 '=' 19500 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 IC50 '=' 130 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 23715 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 48 nM
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 48 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 3 nM
Q9WTR4 BXGT021930 Transporter unreviewed - Slc6a2 Ki '=' 167 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 '=' 4400 nM
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Inhibition '=' 44 %
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki '=' 440 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Inhibition '>' 50 %
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 180 nM
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki '=' 3981 nM
P23944 BXGT008930 Alpha-1D adrenergic receptor reviewed - Adra1d Ki '=' 3981 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki '=' 3981 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 5 nM
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
P08683 BXGT006811 Cytochrome P450 2C11 reviewed - Cyp2c11 mechanism based inhibition - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 '=' 6000 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Inhibition '=' 23 %
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 10 nM
Q9WTR4 BXGT021930 Transporter unreviewed - Slc6a2 Ki '=' 794 nM
P42858 BXGT010341 Huntingtin reviewed - HTT Potency '=' 35481 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 0 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 2 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 2 nM
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 '>' 10000 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 115500 nM
P23977 BXGT008936 Sodium-dependent dopamine transporter reviewed - Slc6a3 IC50 '=' 6000 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Inhibition '=' 31 %
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Inhibition '=' 20 %
P08908 BXGT006837 5-hydroxytryptamine receptor 1A reviewed G-protein coupled receptor HTR1A Ki - - -
Q63380 BXGT016069 Transporter unreviewed - NET Ki '=' 158 nM
P61169 BXGT011367 D(2) dopamine receptor reviewed - Drd2 IC50 '>' 100 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 7 nM
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Activity '=' 210 %
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 1 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 '=' 851 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 563 nM
Q63380 BXGT016069 Transporter unreviewed - NET Ki '=' 2000 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 21 %
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 14381 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Inhibition '=' 1 %
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P46098 BXGT010507 5-hydroxytryptamine receptor 3A reviewed Ion channel HTR3A Inhibition '>' 50 %
P23977 BXGT008936 Sodium-dependent dopamine transporter reviewed - Slc6a3 Ki '>' 2500 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 22 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 32 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 1513 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki '=' 2000 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 3 nM
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 IC50 '=' 133000 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 16 nM
Q9WTR4 BXGT021930 Transporter unreviewed - Slc6a2 Ki '=' 143 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 5200 nM
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P23977 BXGT008936 Sodium-dependent dopamine transporter reviewed - Slc6a3 Ki '=' 4580 nM
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 '=' 1661 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 0 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C IC50 '=' 5400 nM
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
P22002 BXGT008717 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed - Cacna1c IC50 '=' 2820 nM
P51589 BXGT010867 Cytochrome P450 2J2 reviewed - CYP2J2 Activity '=' 87 %
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 4410 nM
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki '=' 6670 nM
P14842 BXGT008059 5-hydroxytryptamine receptor 2A reviewed - Htr2a Ki '>' 1000 nM
P08909 BXGT006838 5-hydroxytryptamine receptor 2C reviewed - Htr2c Ki '>' 1000 nM
P30994 BXGT009493 5-hydroxytryptamine receptor 2B reviewed - Htr2b Ki '>' 1000 nM
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 '=' 1358 nM
P14842 BXGT008059 5-hydroxytryptamine receptor 2A reviewed - Htr2a IC50 '>' 100 nM
P08909 BXGT006838 5-hydroxytryptamine receptor 2C reviewed - Htr2c IC50 '>' 100 nM
P30994 BXGT009493 5-hydroxytryptamine receptor 2B reviewed - Htr2b IC50 '>' 100 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 '=' 9120 nM
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 41 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 3 nM
O15439 BXGT004169 Multidrug resistance-associated protein 4 reviewed Transporter ABCC4 IC50 '=' 133000 nM
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki '=' 55 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 2 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 IC50 '=' 15 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 2 nM
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 26121 nM
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 '>' 100 nM
P23944 BXGT008930 Alpha-1D adrenergic receptor reviewed - Adra1d IC50 '>' 100 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 '>' 100 nM
P23977 BXGT008936 Sodium-dependent dopamine transporter reviewed - Slc6a3 Ki '=' 1092 nM
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki '=' 5260 nM
P23944 BXGT008930 Alpha-1D adrenergic receptor reviewed - Adra1d Ki '=' 5260 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki '=' 5260 nM
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Kd '=' 240 nM
Q61327 BXGT016017 Sodium-dependent dopamine transporter reviewed - Slc6a3 Ki '>' 2000 nM
Q61327 BXGT016017 Sodium-dependent dopamine transporter reviewed - Slc6a3 Ki '=' 10 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Inhibition - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki '=' 2620 nM
P23944 BXGT008930 Alpha-1D adrenergic receptor reviewed - Adra1d Ki '=' 2620 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki '=' 2620 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Inhibition '=' 36 %
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Kd '=' 3600 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 14 nM
P23977 BXGT008936 Sodium-dependent dopamine transporter reviewed - Slc6a3 Ki '=' 3050 nM
P61169 BXGT011367 D(2) dopamine receptor reviewed - Drd2 Inhibition '=' 12 %
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 7 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 14125 nM
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 12 nM
P02770 BXGT005957 Serum albumin reviewed - Alb Kd '=' 36100 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 150 nM
P22909 BXGT008818 Alpha-2A adrenergic receptor reviewed - Adra2a Ki '=' 1920 nM
P19328 BXGT008473 Alpha-2B adrenergic receptor reviewed - Adra2b Ki '=' 1920 nM
P22086 BXGT008728 Alpha-2C adrenergic receptor reviewed - Adra2c Ki '=' 1920 nM
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Activity '=' 175 %
P22909 BXGT008818 Alpha-2A adrenergic receptor reviewed - Adra2a Ki '=' 5011 nM
P19328 BXGT008473 Alpha-2B adrenergic receptor reviewed - Adra2b Ki '=' 5011 nM
P22086 BXGT008728 Alpha-2C adrenergic receptor reviewed - Adra2c Ki '=' 5011 nM
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 143800 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 7 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 6309 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Inhibition '>' 50 %
P08908 BXGT006837 5-hydroxytryptamine receptor 1A reviewed G-protein coupled receptor HTR1A Emax - - -
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 IC50 '=' 6 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Inhibition '<' 10 %
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 2 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
Q9WTR4 BXGT021930 Transporter unreviewed - Slc6a2 Ratio '=' 24 -
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ratio '=' 24 -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P22830 BXGT008809 Ferrochelatase, mitochondrial reviewed Enzyme FECH Inhibition - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki '=' 762 nM
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 Ki '=' 12 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Inhibition - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 '=' 18400 nM
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 reviewed Transporter NPC1 Potency '=' 58047 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 '=' 3595 nM
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 '=' 700 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 25118 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 19952 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Inhibition '=' 5 %
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki '=' 3764 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 281 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 12286 nM
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Inhibition '=' 8 %
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 1122 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Inhibition '=' 12 %
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Inhibition '=' 89 %
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Inhibition '=' 84 %
O95069 BXGT005348 Potassium channel subfamily K member 2 reviewed Ion channel KCNK2 IC50 '=' 14000 nM
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Inhibition '=' 22 %
P31652 BXGT009565 Sodium-dependent serotonin transporter reviewed - Slc6a4 IC50 '=' 8300 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 FC '=' 0 -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Inhibition '=' 5 %
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 3100 nM
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 10621 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 mechanism based inhibition - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ratio IC50 '>' 5 -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ratio IC50 '>' 5 -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 '=' 40 nM
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ratio IC50 '=' 2 -
P25122 BXGT009026 Potassium voltage-gated channel subfamily C member 1 reviewed - Kcnc1 IC50 '=' 13100 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 98 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 16788 nM
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '>' 135000 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 14 %
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 1412 nM
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 reviewed Transporter ABCC3 IC50 '=' 133000 nM
P51589 BXGT010867 Cytochrome P450 2J2 reviewed - CYP2J2 Activity '=' 44 %
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
O95069 BXGT005348 Potassium channel subfamily K member 2 reviewed Ion channel KCNK2 IC50 '=' 19000 nM
Q9NPC2 BXGT021150 Potassium channel subfamily K member 9 reviewed Ion channel KCNK9 Inhibition '=' 31 %
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 77 %
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 5 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Inhibition '=' 6 %
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki '=' 1 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 3 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 EC50 '=' 2 nM
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 55 %
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 '=' 8 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Inhibition '=' 5 %
P08909 BXGT006838 5-hydroxytryptamine receptor 2C reviewed - Htr2c Ki '=' 109 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 10 nM
P51589 BXGT010867 Cytochrome P450 2J2 reviewed - CYP2J2 IC50 '>' 50000 nM
P08397 BXGT006768 Porphobilinogen deaminase reviewed Enzyme HMBS Inhibition - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Inhibition '<' 10 %
P20813 BXGT008603 Cytochrome P450 2B6 reviewed - CYP2B6 Inhibition '<' 10 %
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 133000 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Inhibition '<' 10 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF05526 Salvia miltiorrhiza Salvia miltiorrhiza Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease