Showing entry for Early-Stage Breast Carcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018237
Disease NameEarly-Stage Breast Carcinoma
Disease CUI IdC2986665
MeSH Codes C04   C17  
Disease Class NameNeoplasms; Skin and Connective Tissue Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O43464 BXGT004595 Serine protease HTRA2, mitochondrial 27429 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01579 BXGT005770 Interferon gamma 3458 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04183 BXGT006166 Thymidine kinase, cytosolic 7083 reviewed Kinase
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20701 BXGT008591 Integrin alpha-L 3683 reviewed
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25815 BXGT009074 Protein S100-P 6286 reviewed Calcium-binding protein
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P30304 BXGT009418 M-phase inducer phosphatase 1 993 reviewed Enzyme
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32322 BXGT009624 Pyrroline-5-carboxylate reductase 1, mitochondrial 5831 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49368 BXGT010701 T-complex protein 1 subunit gamma 7203 reviewed Chaperone
P50479 BXGT010804 PDZ and LIM domain protein 4 8572 reviewed Cellular structure
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P78504 BXGT011844 Protein jagged-1 182 reviewed
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16658 BXGT013651 Fascin 6624 reviewed Cellular structure
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q99623 BXGT019941 Prohibitin-2 11331 reviewed
Q99933 BXGT019976 BAG family molecular chaperone regulator 1 573 reviewed
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UHI8 BXGT021701 A disintegrin and metalloproteinase with thrombospondin motifs 1 9510 reviewed Enzyme
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y6A5 BXGT022325 Transforming acidic coiled-coil-containing protein 3 10460 reviewed
Q9Y6D6 BXGT022326 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 10565 reviewed
Q9Y6Q9 BXGT022338 Nuclear receptor coactivator 3 8202 reviewed Kinase
O00308 BXGT023349 NEDD4-like E3 ubiquitin-protein ligase WWP2 11060 reviewed Enzyme
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease