Showing entry for Bilateral cataracts (disorder)


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD009166
Disease NameBilateral cataracts (disorder)
Disease CUI IdC0521707
MeSH Codes C11  
Disease Class NameEye Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15269 BXGT004145 Serine palmitoyltransferase 1 10558 reviewed Enzyme
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01308 BXGT005749 Insulin 3630 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04264 BXGT006176 Keratin, type II cytoskeletal 1 3848 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P07902 BXGT006697 Galactose-1-phosphate uridylyltransferase 2592 reviewed Enzyme
P08572 BXGT006791 Collagen alpha-2(IV) chain 1284 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P17655 BXGT008325 Calpain-2 catalytic subunit 824 reviewed Enzyme
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P21709 BXGT008685 Ephrin type-A receptor 1 2041 reviewed Kinase
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P30041 BXGT009393 Peroxiredoxin-6 9588 reviewed Enzyme
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P32019 BXGT009595 Type II inositol 1,4,5-trisphosphate 5-phosphatase 3633 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35579 BXGT009852 Myosin-9 4627 reviewed
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 7535 reviewed Kinase
P48449 BXGT010632 Lanosterol synthase 4047 reviewed
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P51570 BXGT010858 Galactokinase 2584 reviewed Kinase
P51787 BXGT010889 Potassium voltage-gated channel subfamily KQT member 1 3784 reviewed Ion channel
P52569 BXGT010934 Cationic amino acid transporter 2 6542 reviewed Transporter
P52803 BXGT010958 Ephrin-A5 1946 reviewed Signaling
P53673 BXGT011010 Beta-crystallin A4 1413 reviewed
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P54886 BXGT011092 Delta-1-pyrroline-5-carboxylate synthase 5832 reviewed Enzyme
P60033 BXGT011286 CD81 antigen 975 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q01831 BXGT012621 DNA repair protein complementing XP-C cells 7508 reviewed Nucleic acid binding
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q08257 BXGT012975 Quinone oxidoreductase 1429 reviewed
Q09013 BXGT013023 Myotonin-protein kinase 1760 reviewed Kinase
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase 7486 reviewed Enzyme
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15125 BXGT013543 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 10682 reviewed Enzyme
Q15126 BXGT013544 Phosphomevalonate kinase 10654 reviewed
Q15582 BXGT013581 Transforming growth factor-beta-induced protein ig-h3 7045 reviewed Signaling
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q6XZF7 BXGT016615 Dynamin-binding protein 23268 reviewed
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NHU6 BXGT018569 Tudor domain-containing protein 7 23424 reviewed Enzyme
Q96BZ9 BXGT019629 TBC1 domain family member 20 128637 reviewed
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9NSE4 BXGT021207 Isoleucine--tRNA ligase, mitochondrial 55699 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
P15260 BXGT023924 Interferon gamma receptor 1 3459 reviewed Receptor
Q9ULV5 BXGT024442 Heat shock factor protein 4 3299 reviewed Transcription factor
P07315 BXGT026109 Gamma-crystallin C 1420 reviewed
Q9UBS0 BXGT026113 Ribosomal protein S6 kinase beta-2 6199 reviewed Kinase
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
P43320 BXGT026151 Beta-crystallin B2 1415 reviewed
P02489 BXGT026168 Alpha-crystallin A chain 1409 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease