Showing entry for Interleukin-5 receptor subunit alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012585
Protein NameInterleukin-5 receptor subunit alpha
Uniport IdQ01344
GeneIL5RA
Gene Id3568
DomainIL6Ra-bind
Pfam PF09240  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
3. Environmental Information Processing 3.2 Signal transduction hsa04630 Jak-STAT signaling pathway
5. Organismal Systems 5.1 Immune system hsa04640 Hematopoietic cell lineage
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0002437 inflammatory response to antigenic stimulus
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0070665 positive regulation of leukocyte proliferation
Biological Process GO:0032674 regulation of interleukin-5 production
Biological Process GO:0007165 signal transduction
molecular function GO:0019955 cytokine binding
molecular function GO:0004896 cytokine receptor activity
molecular function GO:0004914 interleukin-5 receptor activity
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-168256 Immune System
R-HSA-449147 Signaling by Interleukins
R-HSA-451927 Interleukin-2 family signaling
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-5673001 RAF/MAP kinase cascade
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-912526 Interleukin receptor SHC signaling
R-HSA-9607240 FLT3 Signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000786 BXGD000010 Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications
C0000822 BXGD000012 Abortion, Tubal Female Urogenital Diseases and Pregnancy Complications
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0008728 BXGD000567 Eosinophilic granulomatosis with polyangiitis Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014457 BXGD000915 Eosinophilia Hemic and Lymphatic Diseases
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0020517 BXGD001415 Hypersensitivity Immune System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0023343 BXGD001635 Leprosy Infections
C0023440 BXGD001646 Acute Erythroblastic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032300 BXGD002346 Lobar Pneumonia Infections; Respiratory Tract Diseases
C0034068 BXGD002457 Pulmonary Eosinophilia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0200638 BXGD004043 Eosinophil count procedure
C0200641 BXGD004044 Blood basophil count (lab test)
C0202177 BXGD004079 Phospholipid measurement
C0206141 BXGD004160 Idiopathic Hypereosinophilic Syndrome Hemic and Lymphatic Diseases
C0340076 BXGD007302 Asthmatic pulmonary eosinophilia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0341106 BXGD007389 Eosinophilic esophagitis Digestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0346421 BXGD007827 Chronic eosinophilic leukemia Neoplasms; Hemic and Lymphatic Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0730607 BXGD009967 Severe chronic obstructive pulmonary disease Respiratory Tract Diseases
C0745091 BXGD010113 Hypereosinophilia Hemic and Lymphatic Diseases
C0861155 BXGD011243 Rhinoconjunctivitis Eye Diseases
C0887898 BXGD011401 Experimental Lung Inflammation Infections; Respiratory Tract Diseases
C1281901 BXGD012133 Fatty acid measurement
C1306759 BXGD012374 Eosinophilic disorder Hemic and Lymphatic Diseases
C1527304 BXGD013266 Allergic Reaction Immune System Diseases
C1827293 BXGD013768 Carcinoma of urinary bladder, invasive Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2347748 BXGD017041 Adult Erythroleukemia
C2699541 BXGD017461 Cytokine Measurement
C2919502 BXGD017875 Familial immunoglobulin A nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3830362 BXGD019751 Early Pregnancy Loss Female Urogenital Diseases and Pregnancy Complications
C3853540 BXGD019820 Aspirin exacerbated respiratory disease Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases; Immune System Diseases; Chemically-Induced Disorders; Otorhinolaryngologic Diseases
C4520840 BXGD023041 Erythroleukemia (Erythroid/Myeloid) Neoplasms; Hemic and Lymphatic Diseases
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005620 beta-D-Glucopyranose 180.16
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein