adisease

Showing entry for Leprosy

General Disease Information
BXGD Id	BXGD001635
Disease Name	Leprosy
Disease CUI Id	C0023343
MeSH Codes	C01
Disease Class Name	Infections
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7 DOID:0050117
Disease Ontology Class Name	disease of anatomical entity; disease by infectious agent
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00148	BXGT003884	ATP-dependent RNA helicase DDX39A	10212	reviewed
O00187	BXGT003890	Mannan-binding lectin serine protease 2	10747	reviewed	Enzyme
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00602	BXGT003940	Ficolin-1	2219	reviewed	Signaling
O15389	BXGT004161	Sialic acid-binding Ig-like lectin 5	8778	reviewed	Receptor
O43353	BXGT004589	Receptor-interacting serine/threonine-protein kinase 2	8767	reviewed	Kinase
O60218	BXGT004858	Aldo-keto reductase family 1 member B10	57016	reviewed	Enzyme
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75636	BXGT005141	Ficolin-3	8547	reviewed	Signaling
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P04083	BXGT006147	Annexin A1	301	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P06703	BXGT006477	Protein S100-A6	6277	reviewed	Calcium-binding protein
P07355	BXGT006609	Annexin A2	302	reviewed
P08603	BXGT006798	Complement factor H	3075	reviewed
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11388	BXGT007697	DNA topoisomerase 2-alpha	7153	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P21333	BXGT008638	Filamin-A	2316	reviewed
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35558	BXGT009847	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	5105	reviewed	Kinase
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36897	BXGT009941	TGF-beta receptor type-1	7046	reviewed	Kinase
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P48147	BXGT010620	Prolyl endopeptidase	5550	reviewed	Enzyme
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P58753	BXGT011247	Toll/interleukin-1 receptor domain-containing adapter protein	114609	reviewed
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61604	BXGT011380	10 kDa heat shock protein, mitochondrial	3336	reviewed	Chaperone
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
P81172	BXGT011935	Hepcidin	57817	reviewed
P82251	BXGT011971	b(0,+)-type amino acid transporter 1	11136	reviewed	Transporter
Q00059	BXGT012512	Transcription factor A, mitochondrial	7019	reviewed
Q01344	BXGT012585	Interleukin-5 receptor subunit alpha	3568	reviewed	Signaling
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q08334	BXGT012981	Interleukin-10 receptor subunit beta	3588	reviewed	Receptor
Q13085	BXGT013309	Acetyl-CoA carboxylase 1	31	reviewed
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13637	BXGT013388	Ras-related protein Rab-32	10981	reviewed
Q13838	BXGT013397	Spliceosome RNA helicase DDX39B	7919	reviewed
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q29980	BXGT013981	MHC class I polypeptide-related sequence B	4277	reviewed
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q7Z434	BXGT017252	Mitochondrial antiviral-signaling protein	57506	reviewed
Q86WV6	BXGT017626	Stimulator of interferon genes protein	340061	reviewed
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q99558	BXGT019934	Mitogen-activated protein kinase kinase kinase 14	9020	reviewed	Kinase
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H0P0	BXGT020439	Cytosolic 5'-nucleotidase 3A	51251	reviewed	Enzyme
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NNX6	BXGT021140	CD209 antigen	30835	reviewed	Receptor
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q96M98	BXGT024941	Parkin coregulated gene protein	135138	reviewed
P27918	BXGT025485	Properdin	5199	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}