adisease

Showing entry for Miscarriage

General Disease Information
BXGD Id	BXGD023523
Disease Name	Miscarriage
Disease CUI Id	C4552766
MeSH Codes	C13
Disease Class Name	Female Urogenital Diseases and Pregnancy Complications
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00141	BXGT003882	Serine/threonine-protein kinase Sgk1	6446	reviewed	Kinase
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00444	BXGT003921	Serine/threonine-protein kinase PLK4	10733	reviewed	Kinase
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O43683	BXGT004614	Mitotic checkpoint serine/threonine-protein kinase BUB1	699	reviewed	Kinase
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O94813	BXGT005337	Slit homolog 2 protein	9353	reviewed
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	2744	reviewed	Enzyme
O95263	BXGT005366	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	8622	reviewed
O96028	BXGT005417	Histone-lysine N-methyltransferase NSD2	7468	reviewed	Epigenetic regulator
P00374	BXGT005520	Dihydrofolate reductase	1719	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00451	BXGT005545	Coagulation factor VIII	2157	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00748	BXGT005640	Coagulation factor XII	2161	reviewed	Enzyme
P00915	BXGT005689	Carbonic anhydrase 1	759	reviewed
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01732	BXGT005782	T-cell surface glycoprotein CD8 alpha chain	925	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02675	BXGT005916	Fibrinogen beta chain	2244	reviewed	Signaling
P02749	BXGT005941	Beta-2-glycoprotein 1	350	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02753	BXGT005945	Retinol-binding protein 4	5950	reviewed	Transporter
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04003	BXGT006124	C4b-binding protein alpha chain	722	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P06744	BXGT006494	Glucose-6-phosphate isomerase	2821	reviewed	Enzyme
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07359	BXGT006612	Platelet glycoprotein Ib alpha chain	2811	reviewed	Receptor
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08700	BXGT006816	Interleukin-3	3562	reviewed
P08758	BXGT006821	Annexin A5	308	reviewed
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09668	BXGT006914	Pro-cathepsin H	1512	reviewed	Enzyme
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10696	BXGT007603	Alkaline phosphatase, germ cell type	251	reviewed	Enzyme
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11137	BXGT007656	Microtubule-associated protein 2	4133	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11586	BXGT007723	C-1-tetrahydrofolate synthase, cytoplasmic	4522	reviewed	Enzyme
P11926	BXGT007760	Ornithine decarboxylase	4953	reviewed	Enzyme
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13489	BXGT007913	Ribonuclease inhibitor	6050	reviewed	Transcription factor
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13688	BXGT007943	Carcinoembryonic antigen-related cell adhesion molecule 1	634	reviewed
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14061	BXGT007979	Estradiol 17-beta-dehydrogenase 1	3292	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16070	BXGT008186	CD44 antigen	960	reviewed
P16144	BXGT008200	Integrin beta-4	3691	reviewed	Receptor
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16471	BXGT008233	Prolactin receptor	5618	reviewed	Signaling
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18564	BXGT008414	Integrin beta-6	3694	reviewed	Receptor
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	6256	reviewed	Nuclear receptor
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P20248	BXGT008554	Cyclin-A2	890	reviewed	Enzyme modulator
P20851	BXGT008609	C4b-binding protein beta chain	725	reviewed
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27540	BXGT009190	Aryl hydrocarbon receptor nuclear translocator	405	reviewed	Transcription factor
P28161	BXGT009234	Glutathione S-transferase Mu 2	2946	reviewed
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29508	BXGT009358	Serpin B3	6317	reviewed	Enzyme modulator
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P31213	BXGT009515	3-oxo-5-alpha-steroid 4-dehydrogenase 2	6716	reviewed	Enzyme
P31260	BXGT009519	Homeobox protein Hox-A10	3206	reviewed
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36871	BXGT009936	Phosphoglucomutase-1	5236	reviewed
P36897	BXGT009941	TGF-beta receptor type-1	7046	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P40199	BXGT010166	Carcinoembryonic antigen-related cell adhesion molecule 6	4680	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41440	BXGT010261	Folate transporter 1	6573	reviewed	Transporter
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P48775	BXGT010662	Tryptophan 2,3-dioxygenase	6999	reviewed	Enzyme
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P51114	BXGT010832	Fragile X mental retardation syndrome-related protein 1	8087	reviewed	Nucleic acid binding
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P52209	BXGT010923	6-phosphogluconate dehydrogenase, decarboxylating	5226	reviewed	Enzyme
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P56537	BXGT011177	Eukaryotic translation initiation factor 6	3692	reviewed	Nucleic acid binding
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60903	BXGT011339	Protein S100-A10	6281	reviewed	Calcium-binding protein
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P78358	BXGT011838	Cancer/testis antigen 1	246100	reviewed
P78380	BXGT011841	Oxidized low-density lipoprotein receptor 1	4973	reviewed
P78417	BXGT011843	Glutathione S-transferase omega-1	9446	reviewed
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q01344	BXGT012585	Interleukin-5 receptor subunit alpha	3568	reviewed	Signaling
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q06520	BXGT012880	Bile salt sulfotransferase	6822	reviewed
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07973	BXGT012952	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	1591	reviewed	Enzyme
Q10469	BXGT013200	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	4247	reviewed	Enzyme
Q13257	BXGT013333	Mitotic spindle assembly checkpoint protein MAD2A	4085	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14676	BXGT013497	Mediator of DNA damage checkpoint protein 1	9656	reviewed
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16647	BXGT013648	Prostacyclin synthase	5740	reviewed
Q16678	BXGT013656	Cytochrome P450 1B1	1545	reviewed	Enzyme
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6GTX8	BXGT016315	Leukocyte-associated immunoglobulin-like receptor 1	3903	reviewed	Receptor
Q6P6C2	BXGT016455	RNA demethylase ALKBH5	54890	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q8N8S7	BXGT018531	Protein enabled homolog	55740	reviewed
Q8NCM8	BXGT018548	Cytoplasmic dynein 2 heavy chain 1	79659	reviewed	Enzyme
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q92854	BXGT019385	Semaphorin-4D	10507	reviewed	Signaling
Q92959	BXGT019400	Solute carrier organic anion transporter family member 2A1	6578	reviewed	Transporter
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q96RJ0	BXGT019728	Trace amine-associated receptor 1	134864	reviewed	G-protein coupled receptor
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9BZP6	BXGT020201	Acidic mammalian chitinase	27159	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H488	BXGT020471	GDP-fucose protein O-fucosyltransferase 1	23509	reviewed
Q9HCN6	BXGT020535	Platelet glycoprotein VI	51206	reviewed	Receptor
Q9NZD4	BXGT021271	Alpha-hemoglobin-stabilizing protein	51327	reviewed	Chaperone
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9P0K1	BXGT021288	Disintegrin and metalloproteinase domain-containing protein 22	53616	reviewed	Enzyme
Q9UHV8	BXGT021706	Galactoside-binding soluble lectin 13	29124	reviewed	Signaling
Q9UIB8	BXGT021715	SLAM family member 5	8832	reviewed
Q9UNN8	BXGT021791	Endothelial protein C receptor	10544	reviewed	Enzyme modulator
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y275	BXGT022223	Tumor necrosis factor ligand superfamily member 13B	10673	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q9UBP0	BXGT023601	Spastin	6683	reviewed	Cellular structure
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q13007	BXGT023883	Interleukin-24	11009	reviewed
Q9UHP3	BXGT024139	Ubiquitin carboxyl-terminal hydrolase 25	29761	reviewed	Enzyme
O60239	BXGT024393	SH3 domain-binding protein 5	9467	reviewed
P08123	BXGT024477	Collagen alpha-2(I) chain	1278	reviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
P20809	BXGT025043	Interleukin-11	3589	reviewed
P19474	BXGT025520	E3 ubiquitin-protein ligase TRIM21	6737	reviewed
Q9UGM3	BXGT025543	Deleted in malignant brain tumors 1 protein	1755	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}