Showing entry for Amyloid-like protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012878
Protein NameAmyloid-like protein 2
Uniport IdQ06481
GeneAPLP2
Gene Id334
DomainAPP_amyloid; APP_Cu_bd; APP_E2; APP_N; Kunitz_BPTI
Pfam PF10515   PF12924   PF12925   PF02177   PF00014  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0002576 platelet degranulation
Biological Process GO:0043687 post-translational protein modification
molecular function GO:0003677 DNA binding
molecular function GO:0008201 heparin binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004867 serine-type endopeptidase inhibitor activity
molecular function GO:0046914 transition metal ion binding
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0070062 extracellular exosome
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0031092 platelet alpha granule membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114608 Platelet degranulation
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76005 Response to elevated platelet cytosolic Ca2+
R-HSA-8957275 Post-translational protein phosphorylation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007274 BXGD000456 Carotid Artery Thrombosis Nervous System Diseases; Cardiovascular Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0020490 BXGD001403 Hyperopia Eye Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0027092 BXGD001971 Myopia Eye Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027746 BXGD002032 Nerve Degeneration Pathological Conditions, Signs and Symptoms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0034951 BXGD002498 Refractive Errors Eye Diseases
C0079102 BXGD003062 Cerebral Thrombosis Nervous System Diseases; Cardiovascular Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151945 BXGD003508 Thrombosis of cerebral veins Nervous System Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206682 BXGD004237 Follicular thyroid carcinoma Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0752125 BXGD010673 Spinocerebellar Ataxia Type 7 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0795687 BXGD010726 Cerebral arterial thrombosis Nervous System Diseases; Cardiovascular Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1285162 BXGD012167 Degenerative disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1843013 BXGD014549 Alzheimer disease, familial, type 3 Nervous System Diseases; Mental Disorders
C2931852 BXGD018079 Clear-cell metastatic renal cell carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3714651 BXGD019423 Follicular Variant Thyroid Gland Papillary Carcinoma Neoplasms; Endocrine System Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002682 Zinc 65.41
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein