Showing entry for Degenerative disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD012167
Disease NameDegenerative disorder
Disease CUI IdC1285162
MeSH Codes C23  
Disease Class NamePathological Conditions, Signs and Symptoms
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O15269 BXGT004145 Serine palmitoyltransferase 1 10558 reviewed Enzyme
O75030 BXGT005096 Microphthalmia-associated transcription factor 4286 reviewed
O75643 BXGT005142 U5 small nuclear ribonucleoprotein 200 kDa helicase 23020 reviewed
O75923 BXGT005166 Dysferlin 8291 reviewed Transporter
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00488 BXGT005552 Coagulation factor XIII A chain 2162 reviewed Enzyme
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04156 BXGT006156 Major prion protein 5621 reviewed
P04181 BXGT006165 Ornithine aminotransferase, mitochondrial 4942 reviewed Enzyme
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05160 BXGT006330 Coagulation factor XIII B chain 2165 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06276 BXGT006430 Cholinesterase 590 reviewed
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07384 BXGT006619 Calpain-1 catalytic subunit 823 reviewed Enzyme
P08100 BXGT006725 Rhodopsin 6010 reviewed G-protein coupled receptor
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P10253 BXGT007550 Lysosomal alpha-glucosidase 2548 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14678 BXGT008038 Small nuclear ribonucleoprotein-associated proteins B and B' 6628 reviewed Nucleic acid binding
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P21333 BXGT008638 Filamin-A 2316 reviewed
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36639 BXGT009930 7,8-dihydro-8-oxoguanine triphosphatase 4521 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42858 BXGT010341 Huntingtin 3064 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P51688 BXGT010883 N-sulphoglucosamine sulphohydrolase 6448 reviewed Enzyme
P52788 BXGT010953 Spermine synthase 6611 reviewed
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P78344 BXGT011835 Eukaryotic translation initiation factor 4 gamma 2 1982 reviewed Nucleic acid binding
P82279 BXGT011972 Protein crumbs homolog 1 23418 reviewed
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q06481 BXGT012878 Amyloid-like protein 2 334 reviewed Enzyme modulator
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q14872 BXGT013511 Metal regulatory transcription factor 1 4520 reviewed Transcription factor
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q8N6T7 BXGT018525 NAD-dependent protein deacetylase sirtuin-6 51548 reviewed Epigenetic regulator
Q8TDS5 BXGT018813 Oxoeicosanoid receptor 1 165140 reviewed G-protein coupled receptor
Q8TDV0 BXGT018815 Probable G-protein coupled receptor 151 134391 reviewed G-protein coupled receptor
Q92834 BXGT019381 X-linked retinitis pigmentosa GTPase regulator 6103 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96QK1 BXGT019720 Vacuolar protein sorting-associated protein 35 55737 reviewed Transporter
Q99574 BXGT019936 Neuroserpin 5274 reviewed Enzyme modulator
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9NZN9 BXGT021280 Aryl-hydrocarbon-interacting protein-like 1 23746 reviewed Chaperone
Q9ULV1 BXGT021764 Frizzled-4 8322 reviewed G-protein coupled receptor
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9Y3I1 BXGT022260 F-box only protein 7 25793 reviewed
P35232 BXGT022663 Prohibitin 5245 reviewed
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9UBP0 BXGT023601 Spastin 6683 reviewed Cellular structure
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease