Showing entry for Nerve Degeneration


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002032
Disease NameNerve Degeneration
Disease CUI IdC0027746
MeSH Codes C23  
Disease Class NamePathological Conditions, Signs and Symptoms
Semantic TypeCell or Molecular Dysfunction
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O15399 BXGT004164 Glutamate receptor ionotropic, NMDA 2D 2906 reviewed Ion channel
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00480 BXGT005551 Ornithine carbamoyltransferase, mitochondrial 5009 reviewed
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01730 BXGT005781 T-cell surface glycoprotein CD4 920 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02792 BXGT005966 Ferritin light chain 2512 reviewed Storage
P03950 BXGT006116 Angiogenin 283 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07737 BXGT006663 Profilin-1 5216 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08236 BXGT006752 Beta-glucuronidase 2990 reviewed
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09651 BXGT006913 Heterogeneous nuclear ribonucleoprotein A1 3178 reviewed
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12830 BXGT007852 Cadherin-1 999 reviewed
P14920 BXGT008067 D-amino-acid oxidase 1610 reviewed
P15036 BXGT008073 Protein C-ets-2 2114 reviewed Transcription factor
P15328 BXGT008108 Folate receptor alpha 2348 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 1141 reviewed Ion channel
P17900 BXGT008353 Ganglioside GM2 activator 2760 reviewed Transporter
P20711 BXGT008594 Aromatic-L-amino-acid decarboxylase 1644 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P22304 BXGT008752 Iduronate 2-sulfatase 3423 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30542 BXGT009436 Adenosine receptor A1 134 reviewed G-protein coupled receptor
P34130 BXGT009752 Neurotrophin-4 4909 reviewed Signaling
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35368 BXGT009822 Alpha-1B adrenergic receptor 147 reviewed G-protein coupled receptor
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P41250 BXGT010244 Glycine--tRNA ligase 2617 reviewed Enzyme
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43005 BXGT010349 Excitatory amino acid transporter 3 6505 reviewed Transporter
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48051 BXGT010611 G protein-activated inward rectifier potassium channel 2 3763 reviewed Ion channel
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49908 BXGT010760 Selenoprotein P 6414 reviewed Extracellular structure
P54764 BXGT011078 Ephrin type-A receptor 4 2043 reviewed Kinase
P54803 BXGT011082 Galactocerebrosidase 2581 reviewed
P54829 BXGT011085 Tyrosine-protein phosphatase non-receptor type 5 84867 reviewed
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P78540 BXGT011848 Arginase-2, mitochondrial 384 reviewed Enzyme
Q01484 BXGT012592 Ankyrin-2 287 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q06481 BXGT012878 Amyloid-like protein 2 334 reviewed Enzyme modulator
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1859 reviewed Kinase
Q14114 BXGT013441 Low-density lipoprotein receptor-related protein 8 7804 reviewed
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14203 BXGT013455 Dynactin subunit 1 1639 reviewed Chaperone
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14833 BXGT013508 Metabotropic glutamate receptor 4 2914 reviewed G-protein coupled receptor
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 8851 reviewed Enzyme modulator
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q16611 BXGT013644 Bcl-2 homologous antagonist/killer 578 reviewed Signaling
Q5JTZ9 BXGT015458 Alanine--tRNA ligase, mitochondrial 57505 reviewed Nucleic acid binding
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96I59 BXGT019675 Probable asparagine--tRNA ligase, mitochondrial 79731 reviewed Enzyme
Q96PY6 BXGT019712 Serine/threonine-protein kinase Nek1 4750 reviewed Kinase
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99757 BXGT019959 Thioredoxin, mitochondrial 25828 reviewed Enzyme
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9BZ23 BXGT020194 Pantothenate kinase 2, mitochondrial 80025 reviewed Kinase
Q9H492 BXGT020472 Microtubule-associated proteins 1A/1B light chain 3A 84557 reviewed Cellular structure
Q9HD40 BXGT020542 O-phosphoseryl-tRNA(Sec) selenium transferase 51091 reviewed
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9Y289 BXGT022226 Sodium-dependent multivitamin transporter 8884 reviewed Transporter
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
Q53GS7 BXGT023762 Nucleoporin GLE1 2733 reviewed Transporter
P21926 BXGT024578 CD9 antigen 928 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease