Showing entry for Neutral and basic amino acid transport protein rBAT


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012943
Protein NameNeutral and basic amino acid transport protein rBAT
Uniport IdQ07837
GeneSLC3A1
Gene Id6519
DomainAlpha-amylase
Pfam PF00128  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04974 Protein digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006865 amino acid transport
Biological Process GO:0015802 basic amino acid transport
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0015811 L-cystine transport
molecular function GO:0015171 amino acid transmembrane transporter activity
molecular function GO:0015174 basic amino acid transmembrane transporter activity
molecular function GO:0003824 catalytic activity
molecular function GO:0015184 L-cystine transmembrane transporter activity
molecular function GO:0044877 protein-containing complex binding
cellular component GO:0031526 brush border membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0005774 vacuolar membrane
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-352230 Amino acid transport across the plasma membrane
R-HSA-382551 Transport of small molecules
R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-5619102 SLC transporter disorders
R-HSA-5619113 Defective SLC3A1 causes cystinuria (CSNU)
R-HSA-5619115 Disorders of transmembrane transporters
R-HSA-5660883 Defective SLC7A9 causes cystinuria (CSNU)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001125 BXGD000024 Acidosis, Lactic Nutritional and Metabolic Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0010691 BXGD000685 Cystinuria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0020505 BXGD001412 Hyperphagia Pathological Conditions, Signs and Symptoms
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020598 BXGD001440 Hypocalcemia Nutritional and Metabolic Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020619 BXGD001447 Hypogonadism Endocrine System Diseases
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024796 BXGD001806 Marfan Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0026351 BXGD001900 Moderate intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027707 BXGD002024 Nephritis, Interstitial Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027709 BXGD002026 Nephrocalcinosis Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0030319 BXGD002208 Panic Disorder Mental Disorders
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0041349 BXGD002920 Nephritis, Tubulointerstitial Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221358 BXGD004450 Long narrow head
C0235659 BXGD004763 Reduced fetal movement Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0238506 BXGD004941 Congenital posterior urethral valves Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0262655 BXGD005264 Recurrent urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0268643 BXGD006021 Cystinuria type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0268645 BXGD006022 Cystinuria, type 3 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0268646 BXGD006023 Isolated cystinuria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0270971 BXGD006146 Floppy infant syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0278660 BXGD006555 Adult Synovial Sarcoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279982 BXGD006702 Childhood Synovial Sarcoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0343239 BXGD007611 Benign congenital hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0451641 BXGD008821 Urolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0456070 BXGD008863 Growth delay
C0497552 BXGD009067 Congenital neurologic anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0557874 BXGD009444 Global developmental delay
C0566620 BXGD009490 Nasal voice
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0686353 BXGD009833 Muscular Dystrophies, Limb-Girdle Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0848548 BXGD010881 hypertensive nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1836542 BXGD014129 Depressed nasal bridge
C1848030 BXGD014902 Hypotonia-Cystinuria Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1850889 BXGD015185 MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2B Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1853738 BXGD015357 Long eyelashes
C1857388 BXGD015699 Cystinuria, Type A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1857389 BXGD015700 Cystinuria, Type B Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1857486 BXGD015710 Low-set, posteriorly rotated ears
C1861403 BXGD016045 Variable expressivity
C1866956 BXGD016428 Aortic root dilation
C1867743 BXGD016470 Premature coronary artery atherosclerosis Cardiovascular Diseases
C2267233 BXGD017017 Neonatal Hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2751582 BXGD017726 Mitochondrial respiratory chain defects
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3494422 BXGD018966 Retrognathia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C3698119 BXGD019365 Inherited aminoaciduria Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C4021733 BXGD020741 Hyperlysinuria
C4025602 BXGD021688 Ornithinuria
C4025635 BXGD021704 Argininuria
C4304537 BXGD022579 2p21 microdeletion syndrome
C4479088 BXGD022926 MYASTHENIC SYNDROME, CONGENITAL, 22
C4551858 BXGD023425 Vesicoureteral Reflux 1 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4755274 BXGD024090 Atypical hypotonia cystinuria syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein