adisease

Showing entry for Retrognathia

General Disease Information
BXGD Id	BXGD018966
Disease Name	Retrognathia
Disease CUI Id	C3494422
MeSH Codes	C16 C05 C07
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
Semantic Type	Anatomical Abnormality
Human Phenotype Ontology Id	HP:0000152 HP:0000924
Human Phenotype Ontology Term	Abnormality of head or neck; Abnormality of the skeletal system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A4D126	BXGT001208	D-ribitol-5-phosphate cytidylyltransferase	729920	reviewed
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O43175	BXGT004575	D-3-phosphoglycerate dehydrogenase	26227	reviewed	Enzyme
O43929	BXGT004638	Origin recognition complex subunit 4	5000	reviewed	Nucleic acid binding
O75496	BXGT005132	Geminin	51053	reviewed
O75530	BXGT005135	Polycomb protein EED	8726	reviewed
O95363	BXGT005375	Phenylalanine--tRNA ligase, mitochondrial	10667	reviewed	Enzyme
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P10826	BXGT007622	Retinoic acid receptor beta	5915	reviewed	Nuclear receptor
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P28300	BXGT009243	Protein-lysine 6-oxidase	4015	reviewed
P31153	BXGT009512	S-adenosylmethionine synthase isoform type-2	4144	reviewed	Enzyme
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P36897	BXGT009941	TGF-beta receptor type-1	7046	reviewed	Kinase
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P48067	BXGT010619	Sodium- and chloride-dependent glycine transporter 1	6536	reviewed	Transporter
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P62736	BXGT011452	Actin, aortic smooth muscle	59	reviewed	Cellular structure
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	18	reviewed	Enzyme
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q07837	BXGT012943	Neutral and basic amino acid transport protein rBAT	6519	reviewed	Transporter
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q10469	BXGT013200	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	4247	reviewed	Enzyme
Q12797	BXGT013266	Aspartyl/asparaginyl beta-hydroxylase	444	reviewed
Q13363	BXGT013344	C-terminal-binding protein 1	1487	reviewed	Transcription factor
Q13415	BXGT013350	Origin recognition complex subunit 1	4998	reviewed	Nucleic acid binding
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q13976	BXGT013409	cGMP-dependent protein kinase 1	5592	reviewed	Kinase
Q14332	BXGT013462	Frizzled-2	2535	reviewed	G-protein coupled receptor
Q15022	BXGT013523	Polycomb protein SUZ12	23512	reviewed	Nucleic acid binding
Q15392	BXGT013566	Delta(24)-sterol reductase	1718	reviewed	Enzyme
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q2M1P5	BXGT014129	Kinesin-like protein KIF7	374654	reviewed
Q6NUK1	BXGT016429	Calcium-binding mitochondrial carrier protein SCaMC-1	29957	reviewed	Transporter
Q6XUX3	BXGT016612	Dual serine/threonine and tyrosine protein kinase	25778	reviewed	Kinase
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9NX14	BXGT021242	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	54539	reviewed	Enzyme
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q53GS7	BXGT023762	Nucleoporin GLE1	2733	reviewed	Transporter
P08123	BXGT024477	Collagen alpha-2(I) chain	1278	reviewed
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q9BYC5	BXGT025656	Alpha-(1,6)-fucosyltransferase	2530	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}