Showing entry for Moderate intellectual disability


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001900
Disease NameModerate intellectual disability
Disease CUI IdC0026351
MeSH Codes C23   C10   F03   F01  
Disease Class NamePathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X 1654 reviewed
O14773 BXGT004096 Tripeptidyl-peptidase 1 1200 reviewed Enzyme
O14936 BXGT004114 Peripheral plasma membrane protein CASK 8573 reviewed Kinase
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O60488 BXGT004878 Long-chain-fatty-acid--CoA ligase 4 2182 reviewed Enzyme
O75030 BXGT005096 Microphthalmia-associated transcription factor 4286 reviewed
O75688 BXGT005145 Protein phosphatase 1B 5495 reviewed Enzyme
O75914 BXGT005165 Serine/threonine-protein kinase PAK 3 5063 reviewed Kinase
P00367 BXGT005517 Glutamate dehydrogenase 1, mitochondrial 2746 reviewed Enzyme
P00387 BXGT005525 NADH-cytochrome b5 reductase 3 1727 reviewed
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P07437 BXGT006624 Tubulin beta chain 203068 reviewed Cellular structure
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11233 BXGT007678 Ras-related protein Ral-A 5898 reviewed Enzyme modulator
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P20711 BXGT008594 Aromatic-L-amino-acid decarboxylase 1644 reviewed
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21675 BXGT008678 Transcription initiation factor TFIID subunit 1 6872 reviewed Kinase
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P22681 BXGT008795 E3 ubiquitin-protein ligase CBL 867 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P35914 BXGT009880 Hydroxymethylglutaryl-CoA lyase, mitochondrial 3155 reviewed Enzyme
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P49591 BXGT010715 Serine--tRNA ligase, cytoplasmic 6301 reviewed Enzyme
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P50135 BXGT010776 Histamine N-methyltransferase 3176 reviewed
P51531 BXGT010851 Probable global transcription activator SNF2L2 6595 reviewed Epigenetic regulator
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P78330 BXGT011833 Phosphoserine phosphatase 5723 reviewed Enzyme
P78508 BXGT011845 ATP-sensitive inward rectifier potassium channel 10 3766 reviewed Ion channel
Q05193 BXGT012810 Dynamin-1 1759 reviewed Enzyme modulator
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q07837 BXGT012943 Neutral and basic amino acid transport protein rBAT 6519 reviewed Transporter
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 5530 reviewed
Q08499 BXGT012988 cAMP-specific 3',5'-cyclic phosphodiesterase 4D 5144 reviewed
Q11203 BXGT013218 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 6487 reviewed
Q12830 BXGT013268 Nucleosome-remodeling factor subunit BPTF 2186 reviewed
Q12840 BXGT013269 Kinesin heavy chain isoform 5A 3798 reviewed Cellular structure
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13509 BXGT013366 Tubulin beta-3 chain 10381 reviewed Cellular structure
Q14643 BXGT013493 Inositol 1,4,5-trisphosphate receptor type 1 3708 reviewed Ion channel
Q15125 BXGT013543 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 10682 reviewed Enzyme
Q16099 BXGT013620 Glutamate receptor ionotropic, kainate 4 2900 reviewed Ion channel
Q8IWQ3 BXGT018355 Serine/threonine-protein kinase BRSK2 9024 reviewed Kinase
Q8N0W4 BXGT018492 Neuroligin-4, X-linked 57502 reviewed
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8NI60 BXGT018572 Atypical kinase COQ8A, mitochondrial 56997 reviewed Kinase
Q92796 BXGT019376 Disks large homolog 3 1741 reviewed
Q96RE7 BXGT019725 Nucleus accumbens-associated protein 1 112939 reviewed
Q96SW2 BXGT019743 Protein cereblon 51185 reviewed Enzyme
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q9BXJ9 BXGT020170 N-alpha-acetyltransferase 15, NatA auxiliary subunit 80155 reviewed Enzyme
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9H1D0 BXGT020445 Transient receptor potential cation channel subfamily V member 6 55503 reviewed Ion channel
Q9H8M5 BXGT020496 Metal transporter CNNM2 54805 reviewed
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NRR6 BXGT021193 Phosphatidylinositol polyphosphate 5-phosphatase type IV 56623 reviewed
Q9NZN1 BXGT021279 Interleukin-1 receptor accessory protein-like 1 11141 reviewed Receptor
Q9UGL1 BXGT021685 Lysine-specific demethylase 5B 10765 reviewed Epigenetic regulator
Q9UGM6 BXGT021687 Tryptophan--tRNA ligase, mitochondrial 10352 reviewed
Q9UHX1 BXGT021707 Poly(U)-binding-splicing factor PUF60 22827 reviewed
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase 23043 reviewed Kinase
Q9UKM7 BXGT021747 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 11253 reviewed Chaperone
Q9ULJ6 BXGT021761 Zinc finger MIZ domain-containing protein 1 57178 reviewed
Q9Y2H9 BXGT022234 Microtubule-associated serine/threonine-protein kinase 1 22983 reviewed Kinase
Q9Y698 BXGT022323 Voltage-dependent calcium channel gamma-2 subunit 10369 reviewed Ion channel
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q9Y5W7 BXGT022783 Sorting nexin-14 57231 reviewed Enzyme modulator
Q7Z624 BXGT022792 Calmodulin-lysine N-methyltransferase 79823 reviewed
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q96DA2 BXGT025522 Ras-related protein Rab-39B 116442 reviewed
Q8TAB3 BXGT025819 Protocadherin-19 57526 reviewed
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
Q8WXI2 BXGT026145 Connector enhancer of kinase suppressor of ras 2 22866 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease