Showing entry for Connective Tissue Diseases


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000631
Disease NameConnective Tissue Diseases
Disease CUI IdC0009782
MeSH Codes C17  
Disease Class NameSkin and Connective Tissue Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00469 BXGT003926 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 5352 reviewed Enzyme
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O60568 BXGT004885 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 8985 reviewed Enzyme
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O75116 BXGT005100 Rho-associated protein kinase 2 9475 reviewed Kinase
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
P00439 BXGT005539 Phenylalanine-4-hydroxylase 5053 reviewed
P00451 BXGT005545 Coagulation factor VIII 2157 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05155 BXGT006328 Plasma protease C1 inhibitor 710 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13674 BXGT007942 Prolyl 4-hydroxylase subunit alpha-1 5033 reviewed
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P15151 BXGT008089 Poliovirus receptor 5817 reviewed
P15941 BXGT008176 Mucin-1 4582 reviewed
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P17676 BXGT008327 CCAAT/enhancer-binding protein beta 1051 reviewed Transcription factor
P20231 BXGT008550 Tryptase beta-2 7177 reviewed
P20273 BXGT008557 B-cell receptor CD22 933 reviewed
P20810 BXGT008602 Calpastatin 831 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21333 BXGT008638 Filamin-A 2316 reviewed
P21796 BXGT008690 Voltage-dependent anion-selective channel protein 1 7416 reviewed
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P35270 BXGT009807 Sepiapterin reductase 6697 reviewed
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P51878 BXGT010902 Caspase-5 838 reviewed Enzyme
P51884 BXGT010903 Lumican 4060 reviewed
P54886 BXGT011092 Delta-1-pyrroline-5-carboxylate synthase 5832 reviewed Enzyme
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q04771 BXGT012783 Activin receptor type-1 90 reviewed Kinase
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 659 reviewed Kinase
Q14839 BXGT013509 Chromodomain-helicase-DNA-binding protein 4 1108 reviewed
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15661 BXGT013588 Tryptase alpha/beta-1 7177 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96PF2 BXGT019708 Testis-specific serine/threonine-protein kinase 2 23617 reviewed Kinase
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NWM8 BXGT021233 Peptidyl-prolyl cis-trans isomerase FKBP14 55033 reviewed
Q9UBV7 BXGT021665 Beta-1,4-galactosyltransferase 7 11285 reviewed
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q9Y3B4 BXGT022255 Splicing factor 3B subunit 6 51639 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q9UM82 BXGT023181 Spermatogenesis-associated protein 2 9825 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q9NR30 BXGT024748 Nucleolar RNA helicase 2 9188 reviewed
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease