adisease

Showing entry for Severe Dengue

General Disease Information
BXGD Id	BXGD001283
Disease Name	Severe Dengue
Disease CUI Id	C0019100
MeSH Codes	C01
Disease Class Name	Infections
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0050117
Disease Ontology Class Name	disease by infectious agent
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75369	BXGT005119	Filamin-B	2317	reviewed
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
O76054	BXGT005172	SEC14-like protein 2	23541	reviewed
O95786	BXGT005396	Probable ATP-dependent RNA helicase DDX58	23586	reviewed
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00746	BXGT005638	Complement factor D	1675	reviewed	Enzyme
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P08603	BXGT006798	Complement factor H	3075	reviewed
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	6256	reviewed	Nuclear receptor
P20231	BXGT008550	Tryptase beta-2	7177	reviewed
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P23946	BXGT008932	Chymase	1215	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P48551	BXGT010645	Interferon alpha/beta receptor 2	3455	reviewed	Receptor
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P58753	BXGT011247	Toll/interleukin-1 receptor domain-containing adapter protein	114609	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P67936	BXGT011570	Tropomyosin alpha-4 chain	7171	reviewed	Cellular structure
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q15661	BXGT013588	Tryptase alpha/beta-1	7177	reviewed
Q16611	BXGT013644	Bcl-2 homologous antagonist/killer	578	reviewed	Signaling
Q29980	BXGT013981	MHC class I polypeptide-related sequence B	4277	reviewed
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q96LD8	BXGT019693	Sentrin-specific protease 8	123228	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9NNX6	BXGT021140	CD209 antigen	30835	reviewed	Receptor
Q9NWB1	BXGT021231	RNA binding protein fox-1 homolog 1	54715	reviewed	Nucleic acid binding
Q9P212	BXGT021297	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1	51196	reviewed	Enzyme
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}