Showing entry for DOSAGE-SENSITIVE SEX REVERSAL


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD014918
Disease NameDOSAGE-SENSITIVE SEX REVERSAL
Disease CUI IdC1848296
MeSH Codes C16   C13   C12   C19  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00482 BXGT003929 Nuclear receptor subfamily 5 group A member 2 2494 reviewed Nuclear receptor
O15553 BXGT004181 Pyrin 4210 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75369 BXGT005119 Filamin-B 2317 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O95150 BXGT005351 Tumor necrosis factor ligand superfamily member 15 9966 reviewed Signaling
O95718 BXGT005392 Steroid hormone receptor ERR2 2103 reviewed Nuclear receptor
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04731 BXGT006251 Metallothionein-1A 4489 reviewed
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08195 BXGT006745 4F2 cell-surface antigen heavy chain 6520 reviewed Transporter
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P09238 BXGT006875 Stromelysin-2 4319 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12830 BXGT007852 Cadherin-1 999 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15538 BXGT008137 Cytochrome P450 11B1, mitochondrial 1584 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P18283 BXGT008395 Glutathione peroxidase 2 2877 reviewed Enzyme
P19099 BXGT008456 Cytochrome P450 11B2, mitochondrial 1585 reviewed
P20231 BXGT008550 Tryptase beta-2 7177 reviewed
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21673 BXGT008676 Diamine acetyltransferase 1 6303 reviewed
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P23946 BXGT008932 Chymase 1215 reviewed Enzyme
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P30536 BXGT009435 Translocator protein 706 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P56199 BXGT011150 Integrin alpha-1 3672 reviewed
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 8140 reviewed Transporter
Q01718 BXGT012609 Adrenocorticotropic hormone receptor 4158 reviewed G-protein coupled receptor
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q07157 BXGT012920 Tight junction protein ZO-1 7082 reviewed Cell-cell junction
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q13887 BXGT013401 Krueppel-like factor 5 688 reviewed Nucleic acid binding
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14527 BXGT013479 Helicase-like transcription factor 6596 reviewed
Q15661 BXGT013588 Tryptase alpha/beta-1 7177 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q29980 BXGT013981 MHC class I polypeptide-related sequence B 4277 reviewed
Q7Z2W7 BXGT017248 Transient receptor potential cation channel subfamily M member 8 79054 reviewed Ion channel
Q8TCT9 BXGT018801 Minor histocompatibility antigen H13 81502 reviewed Enzyme
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96KS0 BXGT019688 Egl nine homolog 2 112398 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96PD4 BXGT019705 Interleukin-17F 112744 reviewed
Q9H015 BXGT020432 Solute carrier family 22 member 4 6583 reviewed Transporter
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NZI8 BXGT021273 Insulin-like growth factor 2 mRNA-binding protein 1 10642 reviewed Enzyme
Q9P212 BXGT021297 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 51196 reviewed Enzyme
Q9UKJ1 BXGT021744 Paired immunoglobulin-like type 2 receptor alpha 29992 reviewed
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y5S8 BXGT022302 NADPH oxidase 1 27035 reviewed
Q9Y6W6 BXGT022342 Dual specificity protein phosphatase 10 11221 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q9BY76 BXGT025687 Angiopoietin-related protein 4 51129 reviewed Signaling
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease