adisease

Showing entry for Pruritus

General Disease Information
BXGD Id	BXGD002419
Disease Name	Pruritus
Disease CUI Id	C0033774
MeSH Codes	C23 C17
Disease Class Name	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0001574
Human Phenotype Ontology Term	Abnormality of the integument
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00204	BXGT003893	Sulfotransferase family cytosolic 2B member 1	6820	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
O95342	BXGT005373	Bile salt export pump	8647	reviewed	Transporter
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01903	BXGT005814	HLA class II histocompatibility antigen, DR alpha chain	3122	reviewed	Immune response
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P12955	BXGT007865	Xaa-Pro dipeptidase	5184	reviewed	Enzyme
P14324	BXGT008005	Farnesyl pyrophosphate synthase	2224	reviewed	Enzyme
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P20231	BXGT008550	Tryptase beta-2	7177	reviewed
P21439	BXGT008649	Phosphatidylcholine translocator ABCB4	5244	reviewed	Transporter
P22413	BXGT008764	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	5167	reviewed	Enzyme
P22830	BXGT008809	Ferrochelatase, mitochondrial	2235	reviewed	Enzyme
P31785	BXGT009577	Cytokine receptor common subunit gamma	3561	reviewed	Signaling
P35052	BXGT009788	Glypican-1	2817	reviewed
P35367	BXGT009821	Histamine H1 receptor	3269	reviewed	G-protein coupled receptor
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P38571	BXGT010054	Lysosomal acid lipase/cholesteryl ester hydrolase	3988	reviewed	Enzyme
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
Q01726	BXGT012610	Melanocyte-stimulating hormone receptor	4157	reviewed	G-protein coupled receptor
Q14032	BXGT013438	Bile acid-CoA:amino acid N-acyltransferase	570	reviewed
Q15126	BXGT013544	Phosphomevalonate kinase	10654	reviewed
Q15661	BXGT013588	Tryptase alpha/beta-1	7177	reviewed
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q8NET8	BXGT018557	Transient receptor potential cation channel subfamily V member 3	162514	reviewed	Ion channel
Q96F46	BXGT019656	Interleukin-17 receptor A	23765	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9H3N8	BXGT020463	Histamine H4 receptor	59340	reviewed	G-protein coupled receptor
Q9HC97	BXGT020527	G-protein coupled receptor 35	2859	reviewed	G-protein coupled receptor
Q9UI33	BXGT021712	Sodium channel protein type 11 subunit alpha	11280	reviewed	Ion channel
Q9ULV0	BXGT021763	Unconventional myosin-Vb	4645	reviewed	Cellular structure
Q9Y5L0	BXGT022296	Transportin-3	23534	reviewed	Transporter
Q9Y5Y9	BXGT022309	Sodium channel protein type 10 subunit alpha	6336	reviewed	Ion channel
P26045	BXGT022810	Tyrosine-protein phosphatase non-receptor type 3	5774	reviewed
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
P16615	BXGT023653	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	488	reviewed	Transporter
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
Q96SD1	BXGT025929	Protein artemis	64421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}