adisease

Showing entry for Dysautonomia

General Disease Information
BXGD Id	BXGD000818
Disease Name	Dysautonomia
Disease CUI Id	C0013363
MeSH Codes	C10
Disease Class Name	Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15269	BXGT004145	Serine palmitoyltransferase 1	10558	reviewed	Enzyme
O43464	BXGT004595	Serine protease HTRA2, mitochondrial	27429	reviewed
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75628	BXGT005140	GTP-binding protein REM 1	28954	reviewed
O75899	BXGT005161	Gamma-aminobutyric acid type B receptor subunit 2	9568	reviewed	G-protein coupled receptor
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01275	BXGT005747	Glucagon	2641	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P04156	BXGT006156	Major prion protein	5621	reviewed
P04278	BXGT006182	Sex hormone-binding globulin	6462	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P15382	BXGT008116	Potassium voltage-gated channel subfamily E member 1	3753	reviewed	Ion channel
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P20231	BXGT008550	Tryptase beta-2	7177	reviewed
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P32297	BXGT009616	Neuronal acetylcholine receptor subunit alpha-3	1136	reviewed	Ion channel
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42702	BXGT010335	Leukemia inhibitory factor receptor	3977	reviewed	Signaling
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P48544	BXGT010641	G protein-activated inward rectifier potassium channel 4	3762	reviewed	Ion channel
P48643	BXGT010650	T-complex protein 1 subunit epsilon	22948	reviewed	Chaperone
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49914	BXGT010762	5-formyltetrahydrofolate cyclo-ligase	10588	reviewed	Enzyme
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P52758	BXGT010951	2-iminobutanoate/2-iminopropanoate deaminase	10247	reviewed
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P78330	BXGT011833	Phosphoserine phosphatase	5723	reviewed	Enzyme
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q01484	BXGT012592	Ankyrin-2	287	reviewed
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q05940	BXGT012846	Synaptic vesicular amine transporter	6571	reviewed	Transporter
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	3757	reviewed	Ion channel
Q12840	BXGT013269	Kinesin heavy chain isoform 5A	3798	reviewed	Cellular structure
Q13509	BXGT013366	Tubulin beta-3 chain	10381	reviewed	Cellular structure
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q15223	BXGT013551	Nectin-1	5818	reviewed
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15661	BXGT013588	Tryptase alpha/beta-1	7177	reviewed
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8IWT1	BXGT018357	Sodium channel subunit beta-4	6330	reviewed	Ion channel
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8WWQ0	BXGT019003	PH-interacting protein	55023	reviewed	Epigenetic regulator
Q8WXF7	BXGT019011	Atlastin-1	51062	reviewed	Enzyme modulator
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99757	BXGT019959	Thioredoxin, mitochondrial	25828	reviewed	Enzyme
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9NXG6	BXGT021246	Transmembrane prolyl 4-hydroxylase	54681	reviewed
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	6328	reviewed	Ion channel
Q9UI33	BXGT021712	Sodium channel protein type 11 subunit alpha	11280	reviewed	Ion channel
Q9Y3I1	BXGT022260	F-box only protein 7	25793	reviewed
Q9Y5Y9	BXGT022309	Sodium channel protein type 10 subunit alpha	6336	reviewed	Ion channel
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}