Showing entry for Collectin-12


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015462
Protein NameCollectin-12
Uniport IdQ5KU26
GeneCOLEC12
Gene Id81035
DomainCollagen; Lectin_C
Pfam PF01391   PF00059  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009756 carbohydrate mediated signaling
Biological Process GO:0071360 cellular response to exogenous dsRNA
Biological Process GO:0006952 defense response
Biological Process GO:0042742 defense response to bacterium
Biological Process GO:0045087 innate immune response
Biological Process GO:0006910 phagocytosis, recognition
Biological Process GO:0060355 positive regulation of cell adhesion molecule production
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0050776 regulation of immune response
Biological Process GO:0034138 toll-like receptor 3 signaling pathway
molecular function GO:0005534 galactose binding
molecular function GO:0030169 low-density lipoprotein particle binding
molecular function GO:0046872 metal ion binding
molecular function GO:0038187 pattern recognition receptor activity
molecular function GO:0005044 scavenger receptor activity
cellular component GO:0005581 collagen trimer
cellular component GO:0030666 endocytic vesicle membrane
cellular component GO:0031012 extracellular matrix
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1280218 Adaptive Immune System
R-HSA-168256 Immune System
R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors
R-HSA-3000480 Scavenging by Class A Receptors
R-HSA-5653656 Vesicle-mediated transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005890 BXGD000345 Body Height
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013170 BXGD000802 Drug habituation Chemically-Induced Disorders; Mental Disorders
C0013222 BXGD000805 Drug Use Disorders Chemically-Induced Disorders; Mental Disorders
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0029231 BXGD002125 Organic Mental Disorders, Substance-Induced Chemically-Induced Disorders; Mental Disorders
C0038580 BXGD002771 Substance Dependence Chemically-Induced Disorders; Mental Disorders
C0038586 BXGD002772 Substance Use Disorders Chemically-Induced Disorders; Mental Disorders
C0234958 BXGD004702 Muscle degeneration Musculoskeletal Diseases
C0236969 BXGD004842 Substance-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0740858 BXGD010012 Substance abuse problem Chemically-Induced Disorders; Mental Disorders
C0856169 BXGD011096 Endothelial dysfunction
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C2985280 BXGD018223 Blood Protein Measurement
C4316881 BXGD022709 Prescription Drug Abuse Chemically-Induced Disorders; Mental Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein