Showing entry for Substance-Related Disorders


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004842
Disease NameSubstance-Related Disorders
Disease CUI IdC0236969
MeSH Codes C25   F03  
Disease Class NameChemically-Induced Disorders; Mental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:150  
Disease Ontology Class Namedisease of mental health
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A1Z1Q3 BXGT001069 ADP-ribose glycohydrolase MACROD2 140733 reviewed
O00519 BXGT003934 Fatty-acid amide hydrolase 1 2166 reviewed
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O43639 BXGT004608 Cytoplasmic protein NCK2 8440 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P05026 BXGT006296 Sodium/potassium-transporting ATPase subunit beta-1 481 reviewed Transporter
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24723 BXGT008989 Protein kinase C eta type 5583 reviewed Kinase
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 1138 reviewed Ion channel
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P41143 BXGT010223 Delta-type opioid receptor 4985 reviewed G-protein coupled receptor
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P41594 BXGT010266 Metabotropic glutamate receptor 5 2915 reviewed G-protein coupled receptor
P41595 BXGT010267 5-hydroxytryptamine receptor 2B 3357 reviewed G-protein coupled receptor
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48058 BXGT010614 Glutamate receptor 4 2893 reviewed Ion channel
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q12908 BXGT013278 Ileal sodium/bile acid cotransporter 6555 reviewed Transporter
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q14123 BXGT013445 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 5137 reviewed
Q14831 BXGT013506 Metabotropic glutamate receptor 7 2917 reviewed G-protein coupled receptor
Q5KU26 BXGT015462 Collectin-12 81035 reviewed Extracellular structure
Q92499 BXGT019350 ATP-dependent RNA helicase DDX1 1653 reviewed
Q92831 BXGT019380 Histone acetyltransferase KAT2B 8850 reviewed
Q96QU1 BXGT019721 Protocadherin-15 65217 reviewed
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 8569 reviewed Kinase
Q9H227 BXGT020447 Cytosolic beta-glucosidase 57733 reviewed Enzyme
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase 9748 reviewed Kinase
Q9NQX4 BXGT021173 Unconventional myosin-Vc 55930 reviewed Cellular structure
Q9NT68 BXGT021210 Teneurin-2 57451 reviewed
Q9NVD7 BXGT021223 Alpha-parvin 55742 reviewed Cellular structure
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q8NEU8 BXGT022976 DCC-interacting protein 13-beta 55198 reviewed
O43172 BXGT026158 U4/U6 small nuclear ribonucleoprotein Prp4 9128 reviewed Nucleic acid binding
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease