Showing entry for Substance abuse problem


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD010012
Disease NameSubstance abuse problem
Disease CUI IdC0740858
MeSH Codes C25   F03  
Disease Class NameChemically-Induced Disorders; Mental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A1Z1Q3 BXGT001069 ADP-ribose glycohydrolase MACROD2 140733 reviewed
O00519 BXGT003934 Fatty-acid amide hydrolase 1 2166 reviewed
O15178 BXGT004135 T-box transcription factor T 6862 reviewed Transcription factor
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
O95405 BXGT005379 Zinc finger FYVE domain-containing protein 9 9372 reviewed
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04732 BXGT006252 Metallothionein-1E 4493 reviewed
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05026 BXGT006296 Sodium/potassium-transporting ATPase subunit beta-1 481 reviewed Transporter
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06276 BXGT006430 Cholinesterase 590 reviewed
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14616 BXGT008026 Insulin receptor-related protein 3645 reviewed Kinase
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P18440 BXGT008404 Arylamine N-acetyltransferase 1 9 reviewed Enzyme
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21918 BXGT008708 D(1B) dopamine receptor 1816 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24723 BXGT008989 Protein kinase C eta type 5583 reviewed Kinase
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27338 BXGT009172 Amine oxidase [flavin-containing] B 4129 reviewed
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28472 BXGT009260 Gamma-aminobutyric acid receptor subunit beta-3 2562 reviewed Ion channel
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 1138 reviewed Ion channel
P30559 BXGT009442 Oxytocin receptor 5021 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P41143 BXGT010223 Delta-type opioid receptor 4985 reviewed G-protein coupled receptor
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P41594 BXGT010266 Metabotropic glutamate receptor 5 2915 reviewed G-protein coupled receptor
P47869 BXGT010590 Gamma-aminobutyric acid receptor subunit alpha-2 2555 reviewed Ion channel
P48058 BXGT010614 Glutamate receptor 4 2893 reviewed Ion channel
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62166 BXGT011412 Neuronal calcium sensor 1 23413 reviewed
P80404 BXGT011907 4-aminobutyrate aminotransferase, mitochondrial 18 reviewed Enzyme
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q12908 BXGT013278 Ileal sodium/bile acid cotransporter 6555 reviewed Transporter
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q14123 BXGT013445 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 5137 reviewed
Q14416 BXGT013468 Metabotropic glutamate receptor 2 2912 reviewed G-protein coupled receptor
Q14831 BXGT013506 Metabotropic glutamate receptor 7 2917 reviewed G-protein coupled receptor
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q5KU26 BXGT015462 Collectin-12 81035 reviewed Extracellular structure
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q92499 BXGT019350 ATP-dependent RNA helicase DDX1 1653 reviewed
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q96QU1 BXGT019721 Protocadherin-15 65217 reviewed
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 8569 reviewed Kinase
Q9H227 BXGT020447 Cytosolic beta-glucosidase 57733 reviewed Enzyme
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase 9748 reviewed Kinase
Q9NQX4 BXGT021173 Unconventional myosin-Vc 55930 reviewed Cellular structure
Q9NT68 BXGT021210 Teneurin-2 57451 reviewed
Q9NVD7 BXGT021223 Alpha-parvin 55742 reviewed Cellular structure
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9Y233 BXGT022210 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 10846 reviewed
Q8NEU8 BXGT022976 DCC-interacting protein 13-beta 55198 reviewed
Q9H6S1 BXGT023027 5-azacytidine-induced protein 2 64343 reviewed
O43172 BXGT026158 U4/U6 small nuclear ribonucleoprotein Prp4 9128 reviewed Nucleic acid binding
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease