Showing entry for Alpha-parvin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021223
Protein NameAlpha-parvin
Uniport IdQ9NVD7
GenePARVA
Gene Id55742
DomainCH
Pfam PF00307  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04510 Focal adhesion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031532 actin cytoskeleton reorganization
Biological Process GO:0070252 actin-mediated cell contraction
Biological Process GO:0030031 cell projection assembly
Biological Process GO:0060271 cilium assembly
Biological Process GO:0007163 establishment or maintenance of cell polarity
Biological Process GO:0034113 heterotypic cell-cell adhesion
Biological Process GO:0003148 outflow tract septum morphogenesis
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0071670 smooth muscle cell chemotaxis
Biological Process GO:0002040 sprouting angiogenesis
Biological Process GO:0034446 substrate adhesion-dependent cell spreading
molecular function GO:0003779 actin binding
molecular function GO:0045296 cadherin binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005925 focal adhesion
cellular component GO:0030027 lamellipodium
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0030018 Z disc
Reactome
Pathway Id Pathway Name
R-HSA-1500931 Cell-Cell communication
R-HSA-446343 Localization of the PINCH-ILK-PARVIN complex to focal adhesions
R-HSA-446353 Cell-extracellular matrix interactions
R-HSA-446388 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
R-HSA-446728 Cell junction organization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013170 BXGD000802 Drug habituation Chemically-Induced Disorders; Mental Disorders
C0013222 BXGD000805 Drug Use Disorders Chemically-Induced Disorders; Mental Disorders
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0029231 BXGD002125 Organic Mental Disorders, Substance-Induced Chemically-Induced Disorders; Mental Disorders
C0038580 BXGD002771 Substance Dependence Chemically-Induced Disorders; Mental Disorders
C0038586 BXGD002772 Substance Use Disorders Chemically-Induced Disorders; Mental Disorders
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0236969 BXGD004842 Substance-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0278488 BXGD006515 Carcinoma breast stage IV
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0740858 BXGD010012 Substance abuse problem Chemically-Induced Disorders; Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4316881 BXGD022709 Prescription Drug Abuse Chemically-Induced Disorders; Mental Disorders
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4733092 BXGD023907 estrogen receptor-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0030612 tetraethylene glycol 194.12
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein