protein

Showing entry for Zinc finger protein ubi-d4

General Target Information
BXGT Id	BXGT023424
Protein Name	Zinc finger protein ubi-d4
Uniport Id	Q92785
Gene	DPF2
Gene Id	5977
Domain	PHD; Requiem_N
Pfam	PF00628 PF14051
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006915	apoptotic process
Biological Process	GO:0097190	apoptotic signaling pathway
Biological Process	GO:1905454	negative regulation of myeloid progenitor cell differentiation
Biological Process	GO:0045892	negative regulation of transcription, DNA-templated
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II
Biological Process	GO:0007399	nervous system development
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
molecular function	GO:0062072	H3K9me3 modified histone binding
molecular function	GO:0004402	histone acetyltransferase activity
molecular function	GO:0042393	histone binding
molecular function	GO:0070577	lysine-acetylated histone binding
molecular function	GO:0046872	metal ion binding
molecular function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function	GO:0003714	transcription corepressor activity
cellular component	GO:0005813	centrosome
cellular component	GO:0005829	cytosol
cellular component	GO:0000123	histone acetyltransferase complex
cellular component	GO:0043231	intracellular membrane-bounded organelle
cellular component	GO:0071565	nBAF complex
cellular component	GO:0000790	nuclear chromatin
cellular component	GO:0005654	nucleoplasm
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0005745	BXGD000331	Blepharoptosis	Eye Diseases
C0008925	BXGD000575	Cleft Palate	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009806	BXGD000633	Constipation	Pathological Conditions, Signs and Symptoms
C0010417	BXGD000670	Cryptorchidism	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010964	BXGD000692	Dandy-Walker Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013336	BXGD000815	Dwarfism	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015934	BXGD001026	Fetal Growth Retardation	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017636	BXGD001131	Glioblastoma	Neoplasms
C0017638	BXGD001132	Glioma	Neoplasms
C0018816	BXGD001234	Heart Septal Defects	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0020295	BXGD001372	Hydronephrosis	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020490	BXGD001403	Hyperopia	Eye Diseases
C0020534	BXGD001421	Orbital separation excessive	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0021400	BXGD001504	Influenza	Infections; Respiratory Tract Diseases
C0022821	BXGD001590	Kyphosis deformity of spine	Musculoskeletal Diseases
C0024433	BXGD001771	Macrostomia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0025958	BXGD001882	Microcephaly	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026827	BXGD001936	Muscle hypotonia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0028738	BXGD002081	Nystagmus	Eye Diseases; Nervous System Diseases
C0033377	BXGD002406	Ptosis	Pathological Conditions, Signs and Symptoms
C0036439	BXGD002615	Scoliosis, unspecified	Musculoskeletal Diseases
C0036572	BXGD002625	Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038379	BXGD002752	Strabismus	Eye Diseases; Nervous System Diseases
C0042769	BXGD002999	Virus Diseases	Infections
C0080174	BXGD003106	Spina Bifida Occulta	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0086543	BXGD003294	Cataract	Eye Diseases
C0152421	BXGD003586	Macrotia
C0202239	BXGD004087	Uric acid measurement (procedure)
C0221357	BXGD004449	Brachydactyly	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0232466	BXGD004543	Feeding difficulties
C0235833	BXGD004775	Congenital diaphragmatic hernia	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0238207	BXGD004894	Ectopic kidney	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0239137	BXGD004965	Coxa valga	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0239234	BXGD004974	Low set ears
C0240340	BXGD005031	Microdontia (disorder)	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0241726	BXGD005110	Delayed ability to walk
C0262444	BXGD005244	Abnormality of the dentition	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0263401	BXGD005298	Cutis marmorata	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases; Cardiovascular Diseases; Wounds and Injuries
C0265338	BXGD005522	Coffin-Siris syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms
C0265535	BXGD005544	Trigonocephaly	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0265610	BXGD005555	Clinodactyly of fingers	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0271907	BXGD006279	Acquired aplastic anemia	Hemic and Lymphatic Diseases
C0278878	BXGD006609	Adult Glioblastoma	Neoplasms
C0280474	BXGD006748	Childhood Glioblastoma	Neoplasms
C0344482	BXGD007678	Hypoplasia of corpus callosum	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0349588	BXGD007933	Short stature
C0423110	BXGD008471	Downward slant of palpebral fissure
C0424295	BXGD008524	Hyperactive behavior	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0431368	BXGD008673	Partial agenesis of corpus callosum	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0431478	BXGD008692	Posteriorly rotated ear
C0432123	BXGD008724	Sagittal craniosynostosis	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0454644	BXGD008850	Delayed speech and language development	Behavior and Behavior Mechanisms
C0557874	BXGD009444	Global developmental delay
C0600104	BXGD009690	Obsessive compulsive behavior	Behavior and Behavior Mechanisms
C0678230	BXGD009750	Congenital Epicanthus
C0747085	BXGD010158	Recurrent otitis media	Otorhinolaryngologic Diseases
C1384666	BXGD012948	hearing impairment	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1621958	BXGD013468	Glioblastoma Multiforme	Neoplasms
C1832348	BXGD013831	Slow-growing hair
C1836542	BXGD014129	Depressed nasal bridge
C1837260	BXGD014214	Prominent forehead
C1839739	BXGD014400	Thick lower lip vermilion
C1839829	BXGD014413	Short distal phalanx of finger
C1842876	BXGD014542	Depressed nasal ridge
C1843367	BXGD014576	Poor school performance
C1845847	BXGD014760	Coarse facial features	Pathological Conditions, Signs and Symptoms
C1849211	BXGD015023	Generalized hirsutism	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1849367	BXGD015046	Nasal bridge wide
C1853487	BXGD015340	Thick eyebrow
C1853738	BXGD015357	Long eyelashes
C1854111	BXGD015381	Broad philtrum
C1857042	BXGD015669	Sparse scalp hair
C1857453	BXGD015703	Renal hypoplasia/aplasia
C1858120	BXGD015774	Generalized hypotonia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1861324	BXGD016029	Short philtrum
C1862095	BXGD016100	Bilateral single transverse palmar creases
C1865017	BXGD016283	Thin upper lip vermilion
C1868577	BXGD016509	Patella aplasia-hypoplasia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1963184	BXGD016688	Nystagmus, CTCAE 3.0
C2062441	BXGD016897	Influenza A
C2674608	BXGD017250	Feeding difficulties in infancy
C2919142	BXGD017867	Short Stature, CTCAE
C3279222	BXGD018751	Aplasia/Hypoplasia of the cerebellum
C3281201	BXGD018889	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms
C3553764	BXGD019187	Joint hyperflexibility
C3714756	BXGD019429	Intellectual Disability	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3806482	BXGD019514	Recurrent respiratory infections	Infections; Respiratory Tract Diseases
C4021735	BXGD020743	Abnormality of the hip bone
C4021792	BXGD020783	Abnormality of the clavicle
C4021801	BXGD020791	Lacrimation abnormality
C4022120	BXGD020881	Aplasia/Hypoplasia of the distal phalanx of the 5th toe
C4023116	BXGD021113	Hypoplastic fifth toenail
C4024507	BXGD021326	Aplasia/Hypoplasia of the distal phalanx of the 5th finger
C4024682	BXGD021368	Hypoplastic fifth fingernail
C4025249	BXGD021604	Abnormality of the intervertebral disk
C4049796	BXGD021951	Abnormality of cardiovascular system morphology	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4551485	BXGD023312	Clinodactyly
C4554036	BXGD023557	Nystagmus, CTCAE 5.0
C4747954	BXGD023974	COFFIN-SIRIS SYNDROME 7

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}