adisease

Showing entry for Hydronephrosis

General Disease Information
BXGD Id	BXGD001372
Disease Name	Hydronephrosis
Disease CUI Id	C0020295
MeSH Codes	C13 C12
Disease Class Name	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000119
Human Phenotype Ontology Term	Abnormality of the genitourinary system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O14684	BXGT004082	Prostaglandin E synthase	9536	reviewed
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O15550	BXGT004179	Lysine-specific demethylase 6A	7403	reviewed	Epigenetic regulator
O43318	BXGT004586	Mitogen-activated protein kinase kinase kinase 7	6885	reviewed	Kinase
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02760	BXGT005948	Protein AMBP	259	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P06576	BXGT006454	ATP synthase subunit beta, mitochondrial	506	reviewed	Transporter
P07093	BXGT006544	Glia-derived nexin	5270	reviewed	Enzyme modulator
P10599	BXGT007583	Thioredoxin	7295	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16144	BXGT008200	Integrin beta-4	3691	reviewed	Receptor
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P21333	BXGT008638	Filamin-A	2316	reviewed
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P21860	BXGT008698	Receptor tyrosine-protein kinase erbB-3	2065	reviewed	Kinase
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P24557	BXGT008976	Thromboxane-A synthase	6916	reviewed
P25774	BXGT009066	Cathepsin S	1520	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35580	BXGT009853	Myosin-10	4628	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P36507	BXGT009923	Dual specificity mitogen-activated protein kinase kinase 2	5605	reviewed	Kinase
P38117	BXGT010027	Electron transfer flavoprotein subunit beta	2109	reviewed	Enzyme
P41227	BXGT010238	N-alpha-acetyltransferase 10	8260	reviewed	Enzyme
P41252	BXGT010245	Isoleucine--tRNA ligase, cytoplasmic	3376	reviewed	Enzyme
P42263	BXGT010295	Glutamate receptor 3	2892	reviewed	Ion channel
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	7498	reviewed	Enzyme
P48048	BXGT010610	ATP-sensitive inward rectifier potassium channel 1	3758	reviewed	Ion channel
P48637	BXGT010649	Glutathione synthetase	2937	reviewed	Enzyme
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P48740	BXGT010659	Mannan-binding lectin serine protease 1	5648	reviewed	Enzyme
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P54764	BXGT011078	Ephrin type-A receptor 4	2043	reviewed	Kinase
P54802	BXGT011081	Alpha-N-acetylglucosaminidase	4669	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P61224	BXGT011370	Ras-related protein Rap-1b	5908	reviewed	Enzyme modulator
P62834	BXGT011464	Ras-related protein Rap-1A	5906	reviewed	Enzyme modulator
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
Q01118	BXGT012570	Sodium channel protein type 7 subunit alpha	6332	reviewed	Ion channel
Q01974	BXGT012628	Tyrosine-protein kinase transmembrane receptor ROR2	4920	reviewed	Kinase
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	5530	reviewed
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q12959	BXGT013283	Disks large homolog 1	1739	reviewed	Receptor
Q13303	BXGT013336	Voltage-gated potassium channel subunit beta-2	8514	reviewed	Ion channel
Q13393	BXGT013346	Phospholipase D1	5337	reviewed
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q15375	BXGT013562	Ephrin type-A receptor 7	2045	reviewed	Kinase
Q15465	BXGT013573	Sonic hedgehog protein	6469	reviewed
Q7Z3B3	BXGT017249	KAT8 regulatory NSL complex subunit 1	284058	reviewed
Q8NCM8	BXGT018548	Cytoplasmic dynein 2 heavy chain 1	79659	reviewed	Enzyme
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q92794	BXGT019375	Histone acetyltransferase KAT6A	7994	reviewed	Enzyme
Q969G3	BXGT019607	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	6605	reviewed
Q96BZ9	BXGT019629	TBC1 domain family member 20	128637	reviewed
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9NP72	BXGT021144	Ras-related protein Rab-18	22931	reviewed
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
Q92785	BXGT023424	Zinc finger protein ubi-d4	5977	reviewed	Enzyme
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}