Showing entry for Joint hyperflexibility


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD019187
Disease NameJoint hyperflexibility
Disease CUI IdC3553764
MeSH Codes   
Disease Class Name
Semantic TypeFinding
Human Phenotype Ontology Id HP:0000924  
Human Phenotype Ontology TermAbnormality of the skeletal system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 10733 reviewed Kinase
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O43929 BXGT004638 Origin recognition complex subunit 4 5000 reviewed Nucleic acid binding
O60706 BXGT004896 ATP-binding cassette sub-family C member 9 10060 reviewed Transporter
O75147 BXGT005102 Obscurin-like protein 1 23363 reviewed
O75369 BXGT005119 Filamin-B 2317 reviewed
O75496 BXGT005132 Geminin 51053 reviewed
O75530 BXGT005135 Polycomb protein EED 8726 reviewed
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
P00736 BXGT005632 Complement C1r subcomponent 715 reviewed Enzyme
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P07237 BXGT006576 Protein disulfide-isomerase 5034 reviewed
P09871 BXGT006932 Complement C1s subcomponent 716 reviewed Enzyme
P10301 BXGT007556 Ras-related protein R-Ras 6237 reviewed Enzyme modulator
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P13224 BXGT007890 Platelet glycoprotein Ib beta chain 2812 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P21333 BXGT008638 Filamin-A 2316 reviewed
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22413 BXGT008764 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5167 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P32322 BXGT009624 Pyrroline-5-carboxylate reductase 1, mitochondrial 5831 reviewed
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P43026 BXGT010351 Growth/differentiation factor 5 8200 reviewed Signaling
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P49917 BXGT010765 DNA ligase 4 3981 reviewed
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54886 BXGT011092 Delta-1-pyrroline-5-carboxylate synthase 5832 reviewed Enzyme
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P61224 BXGT011370 Ras-related protein Rap-1b 5908 reviewed Enzyme modulator
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q02224 BXGT012643 Centromere-associated protein E 1062 reviewed Cellular structure
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q07889 BXGT012946 Son of sevenless homolog 1 6654 reviewed Enzyme modulator
Q13415 BXGT013350 Origin recognition complex subunit 1 4998 reviewed Nucleic acid binding
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q15652 BXGT013587 Probable JmjC domain-containing histone demethylation protein 2C 221037 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q8IWS0 BXGT018356 PHD finger protein 6 84295 reviewed Nucleic acid binding
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8WVQ1 BXGT018996 Soluble calcium-activated nucleotidase 1 124583 reviewed
Q92963 BXGT019401 GTP-binding protein Rit1 6016 reviewed Enzyme modulator
Q969G3 BXGT019607 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 6605 reviewed
Q9H6X2 BXGT020486 Anthrax toxin receptor 1 84168 reviewed Receptor
Q9UBV7 BXGT021665 Beta-1,4-galactosyltransferase 7 11285 reviewed
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q92785 BXGT023424 Zinc finger protein ubi-d4 5977 reviewed Enzyme
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
Q14807 BXGT024966 Kinesin-like protein KIF22 3835 reviewed Cellular structure
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
P58215 BXGT026106 Lysyl oxidase homolog 3 84695 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease