Showing entry for Kyphosis deformity of spine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001590
Disease NameKyphosis deformity of spine
Disease CUI IdC0022821
MeSH Codes C05  
Disease Class NameMusculoskeletal Diseases
Semantic TypeAnatomical Abnormality
Human Phenotype Ontology Id HP:0000924  
Human Phenotype Ontology TermAbnormality of the skeletal system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00459 BXGT003924 Phosphatidylinositol 3-kinase regulatory subunit beta 5296 reviewed Enzyme modulator
O00469 BXGT003926 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 5352 reviewed Enzyme
O14656 BXGT004080 Torsin-1A 1861 reviewed Chaperone
O14764 BXGT004094 Gamma-aminobutyric acid receptor subunit delta 2563 reviewed Ion channel
O14770 BXGT004095 Homeobox protein Meis2 4212 reviewed Enzyme
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O75147 BXGT005102 Obscurin-like protein 1 23363 reviewed
O75844 BXGT005156 CAAX prenyl protease 1 homolog 10269 reviewed Enzyme
O75923 BXGT005166 Dysferlin 8291 reviewed Transporter
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
O96028 BXGT005417 Histone-lysine N-methyltransferase NSD2 7468 reviewed Epigenetic regulator
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04066 BXGT006142 Tissue alpha-L-fucosidase 2517 reviewed
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05452 BXGT006362 Tetranectin 7123 reviewed Extracellular structure
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P07237 BXGT006576 Protein disulfide-isomerase 5034 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07510 BXGT006631 Acetylcholine receptor subunit gamma 1146 reviewed Ion channel
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08034 BXGT006716 Gap junction beta-1 protein 2705 reviewed Cell-cell junction
P08174 BXGT006739 Complement decay-accelerating factor 1604 reviewed
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10619 BXGT007589 Lysosomal protective protein 5476 reviewed Enzyme
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P14678 BXGT008038 Small nuclear ribonucleoprotein-associated proteins B and B' 6628 reviewed Nucleic acid binding
P14920 BXGT008067 D-amino-acid oxidase 1610 reviewed
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P20933 BXGT008618 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase 175 reviewed Enzyme
P21675 BXGT008678 Transcription initiation factor TFIID subunit 1 6872 reviewed Kinase
P22304 BXGT008752 Iduronate 2-sulfatase 3423 reviewed
P22314 BXGT008755 Ubiquitin-like modifier-activating enzyme 1 7317 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P23246 BXGT008840 Splicing factor, proline- and glutamine-rich 6421 reviewed Nucleic acid binding
P23284 BXGT008845 Peptidyl-prolyl cis-trans isomerase B 5479 reviewed
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P33981 BXGT009744 Dual specificity protein kinase TTK 7272 reviewed Kinase
P34059 BXGT009749 N-acetylgalactosamine-6-sulfatase 2588 reviewed Enzyme
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P41227 BXGT010238 N-alpha-acetyltransferase 10 8260 reviewed Enzyme
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42858 BXGT010341 Huntingtin 3064 reviewed
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P46939 BXGT010555 Utrophin 7402 reviewed
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P52788 BXGT010953 Spermine synthase 6611 reviewed
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60891 BXGT011337 Ribose-phosphate pyrophosphokinase 1 5631 reviewed Kinase
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P68133 BXGT011578 Actin, alpha skeletal muscle 58 reviewed Cellular structure
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q01974 BXGT012628 Tyrosine-protein kinase transmembrane receptor ROR2 4920 reviewed Kinase
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q03468 BXGT012716 DNA excision repair protein ERCC-6 2074 reviewed
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q13303 BXGT013336 Voltage-gated potassium channel subunit beta-2 8514 reviewed Ion channel
Q13363 BXGT013344 C-terminal-binding protein 1 1487 reviewed Transcription factor
Q13510 BXGT013367 Acid ceramidase 427 reviewed Enzyme
Q14108 BXGT013440 Lysosome membrane protein 2 950 reviewed Receptor
Q15125 BXGT013543 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 10682 reviewed Enzyme
Q15233 BXGT013552 Non-POU domain-containing octamer-binding protein 4841 reviewed Nucleic acid binding
Q15751 BXGT013593 Probable E3 ubiquitin-protein ligase HERC1 8925 reviewed Enzyme modulator
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q2M385 BXGT014131 Macrophage-expressed gene 1 protein 219972 reviewed
Q32P28 BXGT014324 Prolyl 3-hydroxylase 1 64175 reviewed Extracellular structure
Q7Z3B3 BXGT017249 KAT8 regulatory NSL complex subunit 1 284058 reviewed
Q86UE8 BXGT017612 Serine/threonine-protein kinase tousled-like 2 11011 reviewed Kinase
Q8IWS0 BXGT018356 PHD finger protein 6 84295 reviewed Nucleic acid binding
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8WVQ1 BXGT018996 Soluble calcium-activated nucleotidase 1 124583 reviewed
Q969G3 BXGT019607 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 6605 reviewed
Q96BI3 BXGT019623 Gamma-secretase subunit APH-1A 51107 reviewed Enzyme modulator
Q96BZ9 BXGT019629 TBC1 domain family member 20 128637 reviewed
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q9BQP7 BXGT020114 Mitochondrial genome maintenance exonuclease 1 92667 reviewed
Q9GZV3 BXGT020427 High affinity choline transporter 1 60482 reviewed Transporter
Q9H8P0 BXGT020497 Polyprenol reductase 79644 reviewed
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9HCR9 BXGT020537 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 50940 reviewed
Q9HD40 BXGT020542 O-phosphoseryl-tRNA(Sec) selenium transferase 51091 reviewed
Q9NP72 BXGT021144 Ras-related protein Rab-18 22931 reviewed
Q9NRF2 BXGT021185 SH2B adapter protein 1 25970 reviewed
Q9NXG6 BXGT021246 Transmembrane prolyl 4-hydroxylase 54681 reviewed
Q9NZJ5 BXGT021275 Eukaryotic translation initiation factor 2-alpha kinase 3 9451 reviewed Kinase
Q9P032 BXGT021286 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 29078 reviewed
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UPT6 BXGT021801 C-Jun-amino-terminal kinase-interacting protein 3 23162 reviewed Enzyme modulator
Q9Y263 BXGT022220 Phospholipase A-2-activating protein 9373 reviewed Enzyme modulator
Q9Y2Z4 BXGT022251 Tyrosine--tRNA ligase, mitochondrial 51067 reviewed Enzyme
Q9Y375 BXGT022253 Complex I intermediate-associated protein 30, mitochondrial 51103 reviewed
Q9Y606 BXGT022312 tRNA pseudouridine synthase A 80324 reviewed Enzyme
P43146 BXGT022852 Netrin receptor DCC 1630 reviewed
Q92785 BXGT023424 Zinc finger protein ubi-d4 5977 reviewed Enzyme
Q59FF6 BXGT023693 Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant 2074 unreviewed
Q53GS7 BXGT023762 Nucleoporin GLE1 2733 reviewed Transporter
Q9Y294 BXGT023981 Histone chaperone ASF1A 25842 reviewed Nucleic acid binding
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q9H9S5 BXGT024623 Fukutin-related protein 79147 reviewed
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
Q14807 BXGT024966 Kinesin-like protein KIF22 3835 reviewed Cellular structure
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q96MS0 BXGT025241 Roundabout homolog 3 64221 reviewed Receptor
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease