Showing entry for Hippuric acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0001273
Compound NameHippuric acid
Structure
FormulaC9H9NO3
InchiKeyQIAFMBKCNZACKA-UHFFFAOYSA-N
SMILESOC(=O)CNC(=O)C1=CC=CC=C1
InchiInChI=1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)
IUPAC2-(phenylformamido)acetic acid
Molecular Weight179.17
Pubchem Id464
Chembl IdCHEMBL461
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50009999
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT006700 Aldo-keto reductase family 1 member B1 reviewed Akr1b1 - 330000 - -
reviewed BXGT018912 Solute carrier family 22 member 6 reviewed Slc22a6 56234 - - -
reviewed BXGT017282 Solute carrier family 22 member 20 reviewed Slc22a20 312000 - - -
reviewed BXGT004543 Solute carrier family 22 member 6 reviewed Slc22a6 27500 - - -
reviewed BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 66000 - - -
reviewed BXGT018912 Solute carrier family 22 member 6 reviewed Slc22a6 55600 - - -
reviewed BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 - 20000 - -
CHEMBL CHEMBL461
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 316 nM
Q8TCC7 BXGT018794 Solute carrier family 22 member 8 reviewed Transporter SLC22A8 Ki '=' 31000 nM
Q8VC69 BXGT018912 Solute carrier family 22 member 6 reviewed - Slc22a6 Ki '=' 55600 nM
Q80UJ1 BXGT017282 Solute carrier family 22 member 20 reviewed - Slc22a20 Ki '=' 312000 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 6309 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 3548 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 3548 nM
Q969S8 BXGT019613 Polyamine deacetylase HDAC10 reviewed Epigenetic regulator HDAC10 Activity '=' 100 %
Q9UKV0 BXGT021750 Histone deacetylase 9 reviewed Epigenetic regulator HDAC9 Activity '=' 100 %
P56524 BXGT011176 Histone deacetylase 4 reviewed Epigenetic regulator HDAC4 Activity '=' 100 %
Q96DB2 BXGT019639 Histone deacetylase 11 reviewed Epigenetic regulator HDAC11 Activity '=' 100 %
Q9BY41 BXGT020180 Histone deacetylase 8 reviewed Epigenetic regulator HDAC8 Activity '=' 100 %
Q8WUI4 BXGT018992 Histone deacetylase 7 reviewed Epigenetic regulator HDAC7 Activity '=' 100 %
Q9UQL6 BXGT021813 Histone deacetylase 5 reviewed Epigenetic regulator HDAC5 Activity '=' 100 %
Q92769 BXGT019370 Histone deacetylase 2 reviewed Epigenetic regulator HDAC2 Activity '=' 100 %
Q9UBN7 BXGT021658 Histone deacetylase 6 reviewed Epigenetic regulator HDAC6 Activity '=' 100 %
O15379 BXGT004159 Histone deacetylase 3 reviewed Epigenetic regulator HDAC3 Activity '=' 100 %
Q13547 BXGT013373 Histone deacetylase 1 reviewed Epigenetic regulator HDAC1 Activity '=' 100 %
Q16719 BXGT013662 Kynureninase reviewed Enzyme KYNU Activity - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 '=' 330000 nM
Q80UJ1 BXGT017282 Solute carrier family 22 member 20 reviewed - Slc22a20 Ki '=' 309029 nM
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Inhibition - - -
Q9R1U7 BXGT021423 Solute carrier family 22 member 8 reviewed - Slc22a8 Activity '=' 24 %
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 Ki '=' 66000 nM
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 Activity - - -
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 Km '=' 24000 nM
Q9R1U7 BXGT021423 Solute carrier family 22 member 8 reviewed - Slc22a8 Ki '=' 19000 nM
O35956 BXGT004543 Solute carrier family 22 member 6 reviewed - Slc22a6 Ki '=' 27500 nM
O35956 BXGT004543 Solute carrier family 22 member 6 reviewed - Slc22a6 Km '=' 28000 nM
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 IC50 '=' 20000 nM
Q8VC69 BXGT018912 Solute carrier family 22 member 6 reviewed - Slc22a6 Ki '=' 56234 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00130 Avocado Persea americana Vegetables
BXGF00192 American cranberry Vaccinium macrocarpon Fruits
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease