Showing entry for Diphenylamine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0004705
Compound NameDiphenylamine
Structure
FormulaC12H11N
InchiKeyDMBHHRLKUKUOEG-UHFFFAOYSA-N
SMILESN(C1=CC=CC=C1)C1=CC=CC=C1
InchiInChI=1S/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H
IUPACN-phenylaniline
Molecular Weight169.22
Pubchem Id11487
Chembl IdCHEMBL38688
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL38688
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q05397 BXGT012815 Focal adhesion kinase 1 reviewed Kinase PTK2 Inhibition '=' 0 %
Q13177 BXGT013323 Serine/threonine-protein kinase PAK 2 reviewed Kinase PAK2 Inhibition '=' 4 %
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial reviewed Kinase PDK1 Inhibition '=' 9 %
Q13464 BXGT013357 Rho-associated protein kinase 1 reviewed Kinase ROCK1 Inhibition '=' 0 %
Q08881 BXGT013012 Tyrosine-protein kinase ITK/TSK reviewed Kinase ITK Inhibition '=' 41 %
P49137 BXGT010680 MAP kinase-activated protein kinase 2 reviewed Kinase MAPKAPK2 Inhibition '=' 7 %
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Inhibition '=' 5 %
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 15 pm/min/mg
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 31622 nM
P52333 BXGT010928 Tyrosine-protein kinase JAK3 reviewed Kinase JAK3 Inhibition '=' 2 %
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform reviewed Kinase PIK3CG Inhibition '=' 2 %
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 Inhibition '=' 17 %
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 2 nM
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Inhibition '=' 25 %
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 reviewed - UGT1A4 Activity '=' 240 pm/min/mg
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 reviewed Kinase ERBB4 Inhibition '=' 44 %
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform reviewed Kinase PIK3CD Inhibition '=' 7 %
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK Inhibition '=' 8 %
P07332 BXGT006601 Tyrosine-protein kinase Fes/Fps reviewed Kinase FES Inhibition '=' 9 %
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 reviewed - UGT1A4 Km '=' 240000 nM
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 reviewed Kinase MAP3K5 Inhibition '=' 2 %
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Inhibition '=' 0 %
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta reviewed Kinase IKBKB Inhibition '=' 0 %
P35503 BXGT009840 UDP-glucuronosyltransferase 1-3 reviewed - UGT1A3 Activity '=' 12 pm/min/mg
P15056 BXGT008075 Serine/threonine-protein kinase B-raf reviewed Kinase BRAF Inhibition '=' 6 %
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 reviewed Kinase PAK1 Inhibition '=' 14 %
O43353 BXGT004589 Receptor-interacting serine/threonine-protein kinase 2 reviewed Kinase RIPK2 Inhibition '=' 6 %
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 reviewed Kinase SGK1 Inhibition '=' 3 %
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform reviewed Kinase PIK3CA Inhibition '=' 20 %
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase reviewed Kinase AKT2 Inhibition '=' 9 %
P80244 BXGT011887 ATP-dependent Clp protease proteolytic subunit reviewed - clpP Potency - 31622 nM
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Inhibition '=' 0 %
P08069 BXGT006723 Insulin-like growth factor 1 receptor reviewed Kinase IGF1R Inhibition '=' 0 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 Inhibition '=' 1 %
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Inhibition '=' 17 %
P01215 BXGT005743 Glycoprotein hormones alpha chain reviewed - CGA Potency - 5011 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 56234 nM
Q96GD4 BXGT019667 Aurora kinase B reviewed Kinase AURKB Inhibition '=' 6 %
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Inhibition '=' 13 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00006 Garden onion Allium cepa Vegetables
BXGF00015 Wild celery Apium graveolens Herbs and Spices
BXGF00038 Tea Camellia sinensis Teas
BXGF00040 Pepper (C. annuum) Capsicum annuum Vegetables
BXGF00054 Lemon Citrus limon Fruits
BXGF00061 Coriander Coriandrum sativum Herbs and Spices
BXGF00522 Narrowleaf cattail Typha angustifolia Vegetables
BXGF04600 Typha orientalis Typha orientalis Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease