Showing entry for 1-(5-Thiophen-2-Ylthiophen-2-Yl)Ethanone


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0022806
Compound Name1-(5-Thiophen-2-Ylthiophen-2-Yl)Ethanone
Structure
FormulaC10H8OS2
InchiKeyGKGAOTYPISAEEK-UHFFFAOYSA-N
SMILESCC(=O)c1ccc(s1)c1cccs1
InchiInChI=1S/C10H8OS2/c1-7(11)8-4-5-10(13-8)9-3-2-6-12-9/h2-6H,1H3
IUPAC1-(5-thiophen-2-ylthiophen-2-yl)ethanone
Molecular Weight208
Pubchem Id606422
Chembl IdCHEMBL1345360
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 54022
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT005431 M1 family aminopeptidase reviewed - - 40020 - -
reviewed BXGT010925 Importin subunit alpha-1 reviewed Transporter KPNA2 - - - 28870
reviewed BXGT008966 Corticotropin-releasing factor-binding protein reviewed Signaling CRHBP - - - >53000
CHEMBL CHEMBL1345360
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 28183 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 44668 nM
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Potency - 31622 nM
Q13148 BXGT013318 TAR DNA-binding protein 43 reviewed - TARDBP Potency - 12589 nM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 35481 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 23109 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 23109 nM
P62826 BXGT011463 GTP-binding nuclear protein Ran reviewed Enzyme modulator RAN Potency - 23109 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 22387 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 35481 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 28183 nM
P02791 BXGT005965 Ferritin light chain reviewed - FTL Potency '=' 25118 nM
P24387 BXGT008966 Corticotropin-releasing factor-binding protein reviewed Signaling CRHBP IC50 '>' 47100 nM
Q13324 BXGT013340 Corticotropin-releasing factor receptor 2 reviewed G-protein coupled receptor CRHR2 IC50 '>' 47100 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 10000 nM
P06280 BXGT006433 Alpha-galactosidase A reviewed - GLA Potency '=' 35481 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 112201 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 112201 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 39810 nM
Q8IEK1 BXGT018263 M1-family alanyl aminopeptidase unreviewed - PF3D7_1311800 IC50 '=' 40020 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 26854 nM
Q9Y468 BXGT022270 Lethal(3)malignant brain tumor-like protein 1 reviewed Epigenetic regulator L3MBTL1 Potency '=' 25118 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 79432 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 12589 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 1778 nM
P24387 BXGT008966 Corticotropin-releasing factor-binding protein reviewed Signaling CRHBP EC50 '>' 53000 nM
Q13324 BXGT013340 Corticotropin-releasing factor receptor 2 reviewed G-protein coupled receptor CRHR2 EC50 '>' 53000 nM
P43220 BXGT010367 Glucagon-like peptide 1 receptor reviewed G-protein coupled receptor GLP1R Potency - 12589 nM
P06280 BXGT006433 Alpha-galactosidase A reviewed - GLA Potency - 35481 nM
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short reviewed - GNAS Potency - 11220 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 14581 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF04907 Echinopsis radix Echinopsis radix Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease