acompound

Showing entry for Calcitriol

General Compound Information
BXGC Id	BXGC0042413
Compound Name	Calcitriol
Structure
Formula	C27H44O3
InchiKey	GMRQFYUYWCNGIN-NKMMMXOESA-N
SMILES	O[C@H]1C[C@H](O)C(=C)/C(=C\C=C\2/CCC[C@]3([C@H]2CC[C@@H]3[C@@H](CCCC(O)(C)C)C)C)/C1
Inchi	InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
IUPAC	(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
Molecular Weight	416.33
Pubchem Id	5280453
Chembl Id	CHEMBL846

Targets of Information Source

DrugBank

DB00136

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	approved; nutraceutical	antagonist
P31260	BXGT009519	Homeobox protein Hox-A10	reviewed	-	HOXA10	approved; nutraceutical	-

PDB

VDX

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P11473	BXGT007709	Vitamin D3 receptor	reviewed	VDR	Nuclear receptor	-	-	0.55	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	VDR	Nuclear receptor	-	-	-	-
P13053	BXGT007878	Vitamin D3 receptor	reviewed	Vdr	-	-	-	0.37	-
Q9PTN2	BXGT021351	Vitamin D3 receptor A	reviewed	vdra	-	-	-	-	-
P18326	BXGT008398	Vitamin D3 dihydroxylase	reviewed	cyp105A1	-	-	-	-	-
P13053	BXGT007878	Vitamin D3 receptor	reviewed	Vdr	-	-	-	-	-

Binding DB

50200182

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	1
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	0.08	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	7.7
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	0.7	-	-
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	1	-	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	0.8	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	322
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	515
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	0.06	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	0.35	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	0.12
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	0.6
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	0.1	-	-
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	0.04	-	-	-
reviewed	BXGT004560	Vitamin D3 receptor	reviewed		VDR	0.025	-	-	-
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	0.05	-	-	-
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	-	-	-	0.2
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	3.9
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	223
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	250
reviewed	BXGT013943	Vitamin D3 receptor	reviewed		VDR	-	-	-	0.05
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	0.1	-	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	10
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	0.3
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	-	-	-	0.3
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	0.01
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	0.065	-
reviewed	BXGT013943	Vitamin D3 receptor	reviewed		VDR	-	-	-	0.071
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	0.5
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	-	-	-	0.05
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	0.555
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	0.0106
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	3.52
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	-	-	-	0.1
reviewed	BXGT001189	Vitamin D3 receptor	reviewed		VDR	-	-	0.07	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	13	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	2.5
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	1.24	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	3.28
reviewed	BXGT007878	Vitamin D3 receptor	reviewed		Vdr	0.2	-	-	-
reviewed	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	-	>10000	-	-
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	3
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	0.026
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	-	-	15
reviewed	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	-	9.3	-	-

CHEMBL

CHEMBL846

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O42392	BXGT004560	Vitamin D3 receptor	reviewed	-	VDR	Activity	'='	100	%
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	Relative binding potency	'='	1	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	3	-
P48281	BXGT010625	Vitamin D3 receptor	reviewed	-	Vdr	FC	'='	27890	-
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	10000	nM
P02774	BXGT005959	Vitamin D-binding protein	reviewed	Transporter	GC	Relative potency	'='	100	-
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Ki	'='	0	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Ki	'='	0	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	EC50	'='	0	nM
P04276	BXGT006181	Vitamin D-binding protein	reviewed	-	Gc	Binding affinity	'='	100	-
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	Binding ratio	'='	1	-
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	21136	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	-	-	-
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	ED50	'='	0	M
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	17782	nM
O94782	BXGT005332	Ubiquitin carboxyl-terminal hydrolase 1	reviewed	Enzyme	USP1	Potency	-	56234	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	10	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	7499	nM
Q07973	BXGT012952	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	reviewed	Enzyme	CYP24A1	Activity	-	-	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	13	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	ED50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Kd	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	9	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Ki	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	1	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	100	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	223	nM
P04276	BXGT006181	Vitamin D-binding protein	reviewed	-	Gc	Inhibition	'='	1	%
O42392	BXGT004560	Vitamin D3 receptor	reviewed	-	VDR	RCI	'='	100	%
Q969S8	BXGT019613	Polyamine deacetylase HDAC10	reviewed	Epigenetic regulator	HDAC10	Activity	-	-	-
Q9UKV0	BXGT021750	Histone deacetylase 9	reviewed	Epigenetic regulator	HDAC9	Activity	-	-	-
P56524	BXGT011176	Histone deacetylase 4	reviewed	Epigenetic regulator	HDAC4	Activity	-	-	-
Q96DB2	BXGT019639	Histone deacetylase 11	reviewed	Epigenetic regulator	HDAC11	Activity	-	-	-
Q9BY41	BXGT020180	Histone deacetylase 8	reviewed	Epigenetic regulator	HDAC8	Activity	-	-	-
Q8WUI4	BXGT018992	Histone deacetylase 7	reviewed	Epigenetic regulator	HDAC7	Activity	-	-	-
Q9UQL6	BXGT021813	Histone deacetylase 5	reviewed	Epigenetic regulator	HDAC5	Activity	-	-	-
Q92769	BXGT019370	Histone deacetylase 2	reviewed	Epigenetic regulator	HDAC2	Activity	-	-	-
Q9UBN7	BXGT021658	Histone deacetylase 6	reviewed	Epigenetic regulator	HDAC6	Activity	-	-	-
O15379	BXGT004159	Histone deacetylase 3	reviewed	Epigenetic regulator	HDAC3	Activity	-	-	-
Q13547	BXGT013373	Histone deacetylase 1	reviewed	Epigenetic regulator	HDAC1	Activity	-	-	-
P04276	BXGT006181	Vitamin D-binding protein	reviewed	-	Gc	B50	'='	4	M
P02774	BXGT005959	Vitamin D-binding protein	reviewed	Transporter	GC	RCI	'='	100	%
O42392	BXGT004560	Vitamin D3 receptor	reviewed	-	VDR	Ki	'='	0	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Delta Tm	'='	8	degrees C
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	ED50	'='	1	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	ED50	'='	0	M
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	Relative potency	'='	100	-
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	Potency	'='	25118	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	7	-
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	Kd	'='	0	nM
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	RBA	'='	100	-
O42392	BXGT004560	Vitamin D3 receptor	reviewed	-	VDR	Binding affinity	'='	100	-
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	Activity	'='	100	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	7	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	EC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	Inhibition	'='	1	%
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Activity	'='	100	%
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	ED50	'='	0	M
P25094	BXGT009014	Peripheral myelin protein 22	reviewed	-	Pmp22	Potency	-	5	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	3	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	3	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	ED50	'='	0	nM
Q962Y6	BXGT019597	Thioredoxin glutathione reductase	unreviewed	-	TGR	Potency	'='	39810	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Ratio Ki	'='	1	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	EC50	'='	0	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	ED50	'='	2	10'-10M
P48281	BXGT010625	Vitamin D3 receptor	reviewed	-	Vdr	Activity	-	-	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	3	nM
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	ED50	'='	0	M
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	22387	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	ED50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	515	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Ratio ED50	'='	1	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	3	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Binding potency	'='	1	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'>'	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	1	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	14160	-
P04276	BXGT006181	Vitamin D-binding protein	reviewed	-	Gc	Binding potency	'='	1	-
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	Activity	'='	100	%
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	10000	nM
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	EC50	'='	0	nM
Q7M3G7	BXGT017013	1,25-dihydroxyvitamin D-3 receptor	unreviewed	-		Activity	'='	100	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	ED50	'='	0	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Ratio EC50	'='	1	-
P02774	BXGT005959	Vitamin D-binding protein	reviewed	Transporter	GC	Kd	'='	24	nM
P02774	BXGT005959	Vitamin D-binding protein	reviewed	Transporter	GC	RCI	'='	100	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Transcriptional activity	'='	100	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	ED50	'='	0	uM
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	Activity	'='	100	-
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	FC	'='	100	-
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	Relative affinity	'='	100	-
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	Binding affinity	'='	100	-
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	EC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	18	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	1	-
P04276	BXGT006181	Vitamin D-binding protein	reviewed	-	Gc	Activity	'='	100	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	15	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	ED50	'='	3	M
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Binding activity	'='	1	-
P02774	BXGT005959	Vitamin D-binding protein	reviewed	Transporter	GC	Binding affinity	'='	100	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	0	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	3	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	0	-
A3RGC1	BXGT001189	Vitamin D3 receptor	reviewed	-	VDR	Inhibition	'='	1	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	-	-	-
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	EC50	'='	0	nM
P10276	BXGT007553	Retinoic acid receptor alpha	reviewed	Nuclear receptor	RARA	Activity	-	-	-
P10826	BXGT007622	Retinoic acid receptor beta	reviewed	Nuclear receptor	RARB	Activity	-	-	-
P13631	BXGT007929	Retinoic acid receptor gamma	reviewed	Nuclear receptor	RARG	Activity	-	-	-
P04276	BXGT006181	Vitamin D-binding protein	reviewed	-	Gc	Relative binding potency	'='	1	-
Q96KQ7	BXGT019687	Histone-lysine N-methyltransferase EHMT2	reviewed	Epigenetic regulator	EHMT2	Potency	-	28183	nM
Q28037	BXGT013943	Vitamin D3 receptor	reviewed	-	VDR	VDR affinity	'='	100	%
O15439	BXGT004169	Multidrug resistance-associated protein 4	reviewed	Transporter	ABCC4	IC50	'='	133000	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	ED50	'='	0	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	9441	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	8	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	1	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	19	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	83	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	21	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	1	nM
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Activity	-	-	-
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Ki	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	9	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	2	nM
O15438	BXGT004168	Canalicular multispecific organic anion transporter 2	reviewed	Transporter	ABCC3	IC50	'='	133000	nM
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	12589	nM
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	Inhibition	'='	45	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Imax	'='	100	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	2	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	reviewed	Nuclear receptor	RXRA	Activity	-	-	-
P48443	BXGT010631	Retinoic acid receptor RXR-gamma	reviewed	Nuclear receptor	RXRG	Activity	-	-	-
P28702	BXGT009287	Retinoic acid receptor RXR-beta	reviewed	Nuclear receptor	RXRB	Activity	-	-	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	1	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Delta Tm	'='	2	degrees C
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	249	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	FC	'='	5	-
Q9PTN2	BXGT021351	Vitamin D3 receptor A	reviewed	-	vdra	EC50	'='	5	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Inhibition	'='	100	%
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Delta Tm	'='	0	degrees C
P13053	BXGT007878	Vitamin D3 receptor	reviewed	-	Vdr	Activity	-	-	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	60	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	55	%
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	IC50	'>'	10000	nM
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'='	39700	nM
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	IC50	'='	133000	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	18	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	13	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	55	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	321	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Inhibition	-	-	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	RBA	'='	100	%
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	reviewed	Nuclear receptor	RXRA	EC50	'='	1	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	1	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	6430	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	EC50	'='	0	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	IC50	'='	1	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	16	%
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	'='	16	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF04150	Erycibe expansa	Erycibe expansa	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}